-
Jones-Mote
- 24hr
- Skin Swelling
- Basophils, Lymphocytes, Mononuclear cells
- Intradermal Ag, Ovalbumin
-
Contact
- 48hr
- Eczema
- Mononuclear cells, Edema, Raised epidermis
- Epidermal: nickel, rubber, poison ivy
-
Tuberculin
- 48 hr
- Local induration and swelling w/wo fever
- Mononuclear cells, lymphocytes and monocytes, reduced macrophages
- Dermal: Tuberculin, Mycobacterial, and leishmanial
-
Granulomatous
- 4 wk
- Skin induration
- Epithelioid cell granuloma, giant cells, macrophages, fibrosis w/wo necrosis
- Persistent Ag or Ag-Ab camplexes in macrophages or "nonimmunologic"
-
IgM
- T ind & TH1
- Serum
- Resist: Preciptin, Primary response
- Complement Fixation
- Pentameric (J chains)
-
IgD
- Receptor for B cells
- B-cell Activation
-
IgG
- TH1, TH2
- Abundant
- Serum, Tissue
- Resist: Opsonin, secondary response
- Complement Fixation
- Opsonin for macrophage, PMN
- Crossing of placenta
-
-
IgA
- TH2
- secretions
- Resist: Protection of mucous membranes
- Complement Fixation
- Mucosal Secretions
- Monomeric (monomers, dimers, trimers, multimers - J chains)
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