Hormonal therapy of prostate cancer showed that 50% of DHT was left in the prostate of males who had their testicles removed. Yet 95% of their blood testosterone levels were reduced by castration. In the absence of testicles, what other tissue source continued to provide androgens to the prostate?
The adrenal glands secrete DHEA which is converted to DHT within the prostate. In normal males, this is a minor source of androgen.