Physiology 5 RS problem set

In the first 10 days of the menstrual cycle, how does estrogen affect the pulsatile release of GnRH from the hypothalamus?

Withdrawal of which of the following hormones results in menstruation?

Immunization to produce antibodies that would bind to FSH and negate its activity is being investigated as a potential male contraceptive. Men immunized in this manner would exhibit ____.

An adult male who can not produce testosterone since early childhood and who has not been treated for this condition will ____.

The two essential hormones for the production of sperm (spermatogenesis) are _____.

In males and females, secretion of luteinizing hormone (LH) by the pituitary is regulated by ____.

In a female patient with an inactivating mutation of the estrogen receptor genes (both alpha and beta), one would expect _____.

Steroid hormones such as estrogen and progesterone _____.

Explain the roles of GnRH, LH and FSH in the production of gametes in the human male and female. What hormone(s) are negatively regulated by inhibin in the male and in the female?

In polycystic ovary disease the ovaries fail to ovulate. This is due to high circulating levels of androgens. What cell type in the ovary secretes androgens? What hormone triggers ovulation?

Hormonal therapy of prostate cancer showed that 50% of DHT was left in the prostate of males who had their testicles removed. Yet 95% of their blood testosterone levels were reduced by castration. In the absence of testicles, what other tissue source continued to provide androgens to the prostate?

Predict the level of FSH in the post-menopausal female.

Why do athletes who dose themselves with excess amounts of weak androgens (such as DHEA) develop breast tissue? What enzyme is involved?

In a young boy diagnosed with precocious puberty, puberty is best delayed by the administration of a long-lasting ____. Why?