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Developmental and Biological Variances
- Infants younger than 6 weeks do not produce tears.
- In an infant a sunken fontanel may indicate dehydration- closes at 12-18 months
- Infants are dependent on others to meet their fluid needs
- Infants have limited ability to dilute and concentrate urine
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Developmental and Biological
- The smaller the child, the greater the proportion of body water to weight and proportion of extracellular fluid to intracellular fluid.
- Infants have a larger proportional surface area of the GI tract than adults-get dehydrated quicker
- Infants have a greater body surface area and higher metabolic rate than adults
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Developmental changes
- GI tract not mature until 4-6 months
- Eruption of teeth (baby 6 mo, lose 6 yr.)
- Volume of stomach(30-90ml, goes up 150 a year)
- Changes in appetite-growth spurts
- fluid is of great importance in children because it makes a greater portion of the child's weight
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When do you increase fluid needs?
- Fever
- Vomiting & Diarrhea
- High-output renal failure
- Diabetes insipidus (DI)- lots of urine
- Burns
- Shock
- Tachypnea
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When do you decrease fluids?
- Congestive heart failure-overload would = dec. resp.
- Renal failure
- Head trauma/ meningitis=inc. ICP.
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Maintenance Requirement of Fluid
- First 10kg----100ml/kg/day
- 10-20 kg------100ml+50ml/kg of body wt. more than 10kg
- >20kg---------150 ml+ 20ml/kg of body wt.>than 20 kg
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What are some signs of dehydration?
- Dry skin and mucus membranes
- Poor skin Turgor
- Sunken eyes (dec. IOP)
- Depressed anterior fontanel
- Gray or ashen in color
- Rapid and weak pulse
- Decreased BP (child compensates 25% body loss, bp does not drop right away)
- Oliguria
- Decreased tears (after 6wks)
- Irritability
- Delayed capillary refill
- Inc. Hgb, Hct
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What is Gastroenteritis?
- A group of clinical syndromes manifested by nausea, vomiting, and diarrhea
- Inflammation of the stomach and intestines
- Rotovirus is the leading cause of pediatric gastroenteritis
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Predisposing Factors of Gastroenteritis
- Poor sanitation
- Improper handling of food
- Daycare-use spray cleaner, soap & water
- Antibiotics
- Previous bowel surgery
- Hospital acquired
- Presence of other infectious processes
- Anxiety-inc. motility
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Viral Agents in Gastroenteritis
- More common in winter
- Rotavirus-most common in children 6-24 months
- Norwalk-affects all ages (daycares, cruise ships)
- adenovirus
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Bacterial agents and gastroenteritis
- More common in summer
- mild to severe symptoms
- Most recover without treatment
- Salmonella (turtles, baby chicks)
- Shigella (oral/fecal, monkeys)
- E-Coli (undercooked foods)
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Hypernatremia in dehydration
- Warm, "doughy" skin texture
- hypertonia
- hyperreflexia
- lethargy with irritability when touched
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Hypokalemia in dehydration
- weakness
- Illeus with abdominal distention
- Cardiac arrhythmias
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Management of Gastroenterititis
- Assessment of dehydration
- Oral rehydration (inc. po fluids if diarrhea inc, give po fluids slowly if vomiting., resume diet slowly)
- Avoid fluid with high carbohydrate and low electrolyte values (pop)
- Advance to normal diet as soon as possible
- Nursing mothers should continue to breast feed
- Use of anti-diarrheal agents discouraged
- Protect skin
- IV therapy for inadequate circulating blood volume
- Hylinex-SQ rehydration (acts quickly)
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Nursing Rehydration interventions
- Assess child's hydration status
- Strickt intake and output
- Daily weights
- Hourly monitoring of IV rate and site of infusion
- *increase fluids if increase in vomiting or diarrhea
- *decrease fluids when taking po fluids or signs of edema
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What is constipation?
- Difficulty passing hardend stool
- May be due to underlying disease
- May occur when trasitioning from formula/breast milk to cow's milk
- More common in toddler years
- management-diet, exercise, behavior modifications
- Encorpresis-retention of stool with recurrent soiling
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What is Hirschsprung's disease?
- Congenital Aganglionic Megacolon
- Absence of autonomic parasympatheic ganglion cells in the mucosal and muscular layers of the colon
- Peristalsis normal
- results in obstruction and dilation of the proximal bowel
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clinical findings of Hirschsprung's disease
- failure to pass meconium
- enlarged, distended abdomen
- vomiting
- fecal mass palpable
- rectum is empty of stool
- anorectal manometry (test the sphincter's reaction to rectal distention)
- Biopsy to confirm diagnosis
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Management of Hirschsprung's disease
- Medical management-monitor F&E balance, May need regular rectal irrigation
- Surgical removal of the agangliionic portion of the bowel
- May need temporary ostomy proximal to the aganglionic segment
- complete correction- pull-through procedure
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Special considerations in Hirschsprung's disease
- May be too malnourised to withstand immediate surgery (High calorie, high protein, low fiber diet OR TPN)
- Enterocolitis
- *Inflammation of the small bowel and colon
- *Leads to ischemia and ulceration of bowel wall
- * surgical emergency if bowel perforation occurs
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What is Gastroesophageal Reflux?
- Retrograde flow of gastric contents into the esophagus
- Effortless vomiting-not having sufficient intraluminar pressure to prevent spitting up
- Failure of the sphincter mechanism at the junction of the esophagus and the stomach
- May see spontaneous improvement by 6-9 months
- GERD-GER with complications (aspiration, apnea)
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Manifestations of GI reflux
- spitting up
- vomiting
- weight loss
- gagging, chocking at the end of feedings
- respiratory problems
- heartburn/irritability
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Diagnostic testing for GI reflux
- pH probe- Probe is placed in the distal esophagus to detect pH changes below 4.0pH is measured and recorded q 4-8 sec.
- UGI-fluroscopic and radiographic examinations of the esophagus, stomach, and small intestine.
- Swallow study-Oral barium or water soluble contrast agent is swallowed. The barium or contrast is observed as it passes through the digestive tract and films are taken.
- Scintiscan -gastric emptying study
- Flexible endoscopy-visualize the internal structures of the esophagus, stomach, and duodenum.
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Management of GI reflux
- Change to soy formula
- Frequent burping
- Small feedings-not over 30 minutes
- Elevate the HOB
- Lay on right side after feeding
- Thicken feeding with rice cereal
- Weight monitoring
- SURGICALNissen Fundoplication-Wrapping the gastric cardia with adjacent portions of the gastric fundus around esophagus (cannot vomit)
- G-Tube-decreases the incidence and discomfort of gas (vents stomach)
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Histamine H-2 receptor antagonist-Medications
- Zantac (Rantidine)
- Pepcid (Famotidine)
- Tagament (Cimetidine)
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H-2 receptor anatongist-Action/Indication
Zanatc, Pepcid, Tagament
Inhibition of the histamine-2 receptor on the gastric parietal cell, thus blocking gastric acid secretion
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Histamine H-2 Receptor antagaonist-Nursing implications
Zantac, Pepcid, Tagment
- May be administered with/out food
- If antacids are perscribed, administer 2 hours before or after H2 antagoinist
- Teach parents to avoid OTC medications without check with healthcare provider
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Histamine H-2 receptor anatgonist-side effect
Zantact, Pepcid, Tagament
- Bradycardia
- Constipation
- Nausea
- Fatigue
- Confusion
- Dizziness
- headache
- Irritability
- Rash
- Thrombocytopenia
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Proton Pump Inhibitors-Medication
- Pravacid (Lanzoprazole)
- Prilosec (Omeprazole)
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Proton Pump Inhibitors-Action
Prevacid, Prilosec
- Inhibits acid secretions, alleviates symptoms and helps to heal esophagitis
- Block the final common pathway of acid production by inhibiting activated proton pumps in the gastric parietal cell canaliculus
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Proton Pump Inhibitors-Nursing implications
Prevacid, Prilosec
- Administer in the morning on an empty stomach
- Teach family to inform HCP if sever diarrhea occurs
- Teach family to inform HCP if changes in urinary elimination, such as pain or discomfort associated with urination occur
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Proton Pump Inhibitors-Side Effects
Prevacid, Prilosec
- Abdominal Pain
- Diarrhea
- Dizziness
- Fatigue
- Headache
- Hematuria
- Nausea
- Proteinuria
- Rash
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Prokinetic Agents-Medication
Reglan (Metoclopramide)
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Prokinetic Agents-Action
Reglan
- Promotes Gastric emptying
- Improves gut motility
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Prokinetic Agents-Side effects
Reglan
- Mild sedation
- Fatigue
- Restlessness
- Nausea
- Rash
- Headache
- Insomnia
- Diarrhea
- Constipation
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Aminosalicylates-Medications
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Aminosalicylates-Indication
Sulfasalazine,meslamine
- Used for anti-inflammatory effect
- Inhibition of prostaglandins known to cause diarrhea and affect mucosal trasport
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Aminosalicylates-Nursing Implication
Sulfasalazine, meslamine
- Administer after meals
- Do not crush or chew sustained released tablets
- Teach patient or parents to supplement daily intake of iron
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Aminosalicylates-side effects
Sulfasalazine, meslamine
- Nausea
- vomiting
- bloody diarrhea
- anorexia
- rash
- headache
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Corticosteroids-Medications
- Prednisone
- Prednisolone
- Hydrocortisone enema
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Corticosteroids-Indication
Prednisone, Prednisolone,hydrocrtisone
- Used for anti-inflammatory effect
- **Main one used**
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Corticosteroids-Nursing implication
Prednisone, Prednisolone,hydrocrtisone
- Administer oral medications with meals to reduce gastric irritation
- Teach family to avoid abrupt discontinuation of medication
- Teach family to report delayed wound healing
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Corticosteroids-Side effects
Prednisone, Prednisolone,hydrocrtisone
- Nausea
- Vomiting
- Cushingoid appearance (moon face)
- immunosuppression
- growth suppression
- hypertension
- acne
- altered mood
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Biological Therapies-Medication
- Tumor necrosis factor-alpha (TNF-alpha)
- Infliximab (Remicade)
- Interleukin-10
- Thalidomide
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Biological Therapies-Indication
TNF-alpha, remicade
Prevents TNF-alpha from binding to its receptors (TNF-alpha have been found in stools of patients with crohn's disease)
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Biological Therapies-Nursing implications
TNF-alpha, remicade
- Reconstitute IV preparation according to manufacture directions and administer according to agency protocol
- D/C IV infusion if infusion reaction is evident (fever, chills, chest pain, hypotension, dyspnea, urticaria)
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Antibiotics-Medications
- Metronidazole
- Ciprofloxacil
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Antibiotics-Indication
Metronidazole, Cipofloxacil
Antibacterial aganst anaerobic bacteria and some gram-negative bacteria
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Antibiotics-Nursing implications
Metronidazole, Cipofloxacil
- Extended release form should not be chewed or crushed
- Administer with food or milk to reduce gastrointestinal distress
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Antibiotics-Side effects
Metronidazole, Cipofloxacil
- Fever
- Headache
- Diarrhea
- Nausea
- Vomiting
- Fungal overgrowth
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