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Anatomy
The study of body structure
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Physiology
Study of how the body functions
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Disease
anything that upsets the normal structure or workings of the body
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cell
the basic unit of all life
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tissue
specialized group of cells
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Metabolism
- all the life sustaining reactions that occur whithin the body
- (all chemical reactions needed to sustain life)
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catabolism
breaking down into simpler compounds
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anabolism
building phase of metabolism
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negative feedback
maintains homeostasis by reversing upward or downward trends in body conditions
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dorsal cavity contains what body cavities?
crainial and spinal cord
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Chemistry
science that deals with the composition and properties of matter
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matter
anything that takes up space
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elements
substances that make up all matter
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atomic number
equal to the number protons
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valence
the number of electrons lost or gained in chemical reactions
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molecule
two or more atoms united on the basis of their electron structures
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compounds
substances composed of two or more different elements
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the universal solvent
water
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solution
when one substance is dissolved in another
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solvent
a dissolving substance
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solute
the substance being dissolved
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suspension
solute material is not dissolved and will settle out
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colloids
molecules do not dissolve but remain evenly distributed in the suspending material
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ionic bond
when electrons are tranferred from one atom to another
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ion
an atom or group of atoms with a positive or negative charge
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cation
any ion that is positively charged
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anion
any negatively charged ion
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electrolytes
compounds formed by ionic bonds that release ions when they are in solution
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covalent bond
a sharing of electrons between the atoms in a molecule
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acid
a chemical substance capable of donating a hydrogen ion
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base
a chemical substance that can accept a hydrogen ion
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acidity
a greater concentration of hydrogen ions
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phospholipids
complex lipids containing phosphorus
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steroid
lipid that contain rings of carbon atoms
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proteins
- the body's structural materials
- amino acids
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enzymes
protiens that are essential for metabolism (organic catalysts)
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denaturation
the alteration of any protien so that it can no longer function
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catalysts
enzymes which increase the speed of chemical reactions
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polar
unequal sharing of electrons
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nonpolar
equal sharing of electrons
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pH scale
- measure of acidity or alkalinity of a solution
- below 7 is acidic
- above 7 is alkaline
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cell
the basic unit of all life
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cytology
the study of cells
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stains
special dyes used to color cells and tissues
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phospholipids
lipids that contain phosphorus
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plasma membrane
phospholipid bilayer containing carbohydrates, protiens, colesterol
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microvilli
short extentions of the cell membrane
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cytoplasm
colloidal suspension inside the cell
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cytosol
fluid portion of cytoplasm (liquid protein)
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mitochondria
- convert energy from nutrients to ATP
- powerplant
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golgi apparatus
layers of membranes, prepares compounds for transport to other parts of the cell or out of the cell
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lysosomes
digest substances whithin the cell
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peroxisomes
breakdown of harmful substances
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vesicles
store materials and move materials into or out of the cell in bulk
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cillia
hairlike projections that move the fluids around the cell
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channels
pores in the membrane that allow specific substances to enter or leave. Certain ions travel thru channels in the membrane.
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phagocytes
cells that engulf bacteria and then use lysosomes to destroy them.
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autolysis
self destruction
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chromosomes
- made up of DNA
- 46 chromosomes (22 pairs and 2 sex)
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diffusion
the movement of particles from a high concentraion to a lower concentration until the equilibrium
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osmosis
- the movement of particles from a lower concentration to a higher concenration
- (diffusion of water thru a semi-permeable membrane)
- (water follows salt)
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filtration
passage of water and dissolved materials thru a membrane as a result of a mechanical (pushing) force on one side.
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facillitated diffusion
movement of materials across the membrane along the concentration gradient using a transporter to speed the process
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active transport
- costs ATP to move materials against the natural flow. requires proteins in the plama membrane to act as transporters.
- (against the concentration)
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isotonic
- solutions with concentrations equal to the concentration of the cytoplasm
- (normal saline and 5% glucose)
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hypotonic
less concentrated
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hypertonic
more concentrated
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hemolysis
red blood cell draws in water and bursts
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crenation
when a cell loses water and shrinks
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mutation
alteration of the genes
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characteristics of life
organization, metabolism, responsiveness, homestasis, growth, reproduction
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meiosis
forms the sex cells (divides the chromosome number in half)
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mitosis
division of somatic cells
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stages of mitosis
- a pro met A telephone
- prophase, metaphase, anaphase, telophase
- prophase- the doubled strands of DNA return to spiral organization and the 2 centrioles move toward opposite ends of the cell
- metaphase- chromosomes line up at the center
- anaphase-centomere splits and duplicated chromosomes move to the ends
- telophase- a membrane appears around each group of seperated chromosomes forming 2 nuclei
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-blast
immature cell, early stage of cell
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mucus
secretions produced by epithelial tissues
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collagen
a flexible white protein
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irregular dense connective tissue
fibrous membranes that cover various organs
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regular dense connective tissue
tendons and ligaments
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tendons
connect muscles to bones
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ligaments
connect bones to other bones
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genome
all the different genes on all the chromosomes collectively
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transporters
shuttle substances such as glucose across the membrane
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receptors
allow for attachment of substances, such as hormones, to the membrane
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enzymes
participate in reactions at the surface of the membrane, break things down
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linkers
give structure to the membrane and attach cells to other cells
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cell identity markers
proteins unique to a person's cells
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smooth ER
involved with the synthesis of lipids
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rough ER
ER with ribosomes attached
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endoplasmic reticulum
a network of membranes located between the nuclear membrane and the plasma membrane
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epithelial tissue
covers, surfaces, lines cavities,and forms glands
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transitional epithelium
capable of great expansion, but returns to it's original form
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matrix
nonliving material between cells containing varying amounts of water, fibers, and hard minerals
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neuroglia
nonconducting support cells of the nervous system
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serous membranes
line the walls of body cavities and are folded back onto the surface of internal organs
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mucous membranes
line tubes and other spaces that are open to the outside of the body
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cutaneous membrane
commonly known as the skin
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mesothelium
- the thin epithelium of serous membranes that is smooth and glistening
- sometimes referred to as the serosa
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the pleurae
line the thorasic cavity and cover each lung
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serous pericardium
forms part of a sac that encloses the heart
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peritoneum
the largest serous membrane. it lines the walls of the abdominal cavity, covers the abdominal organs, and forms supporting and protective structures within the abdomin
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parietal layer
attached to the wall of a cavity or sac
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visceral layer
attached to an organ
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mucosa
the mucous membrane of an organ
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synovial membranes
thin connective tissue membranes that line the joint cavities
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meninges
several membranous layers covering the brain and the spinal
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fascia
referres to fiberous bands that support organs and hold them in place
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fiberous pericardium
forms the cavity that encloses the heart
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periosteum
the membrane surrounding a bone
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perichondrium
the membrane around cartilage
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neoplasm
any abnormal growth of cells
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benign
tumor confined to a local area and does not spread
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papilloma
a tumor that grows in epithelium as a projecting mass
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lipoma
tumor originating in fatty tissue
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nevus
a small skin tumor that can appear in a variety of tissues (usually harmless)
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carcinoma
cancer originating in epithelium
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sarcoma
cancers of connective tissue
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disease
abnormality of the structure or function of a part, organ, or system
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predisposing causes of disease
age, gender, heredity, living conditions and habits, emotional disturbance, physical, and chemical damage, and preexisting illness
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pathophysiology
combined study of the relationship oa disease's pathologic and physiologic aspects
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etiology
the study of the cause of a disease
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acute
relativlely servere but usually lasting a short time
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chronic
less severe but likely to be continuous or recurring for long periods
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subacute
between acute and chronic
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idiopathic
without known cause
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iatrogenic disease
ressults from the adverse effects of treatment
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epidemiology
study of diseases in populations
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incidence
the number of new desease cases in a particular population during a specific time period
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prevalence
the overall frequency of a disease in a given group
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mortality rate
the percentage of the population that dies from a given disease whithin a given time period
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epidemic
many people within a given region acquire a certain disease at the same time
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endemic
a given disease is found to a lesser extent but continuously in a particular region
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pandemic
a disease that is prevalent throughout an entire country or continent, or the whole world
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diagnosis
reaching a conclusion as to the nature or identity of the illness
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symptoms
subjective disease conditions noted by the patient (subject)
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sign
objective manifestions that can be observed. (they can be measured)
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syndrome
a characteristic group of symptoms and signs that accompanies a disease
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prognosis
a prediction of a probable outcome of a disease
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therapy
prescribed course of treatment
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microorganisms
a tiny living thing to be seen by the naked eye
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pathogenic
microorganisms that cause illness or disease
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vector
an insect or other animal that transmits a disease-causing organism from one host to another
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bacteria
primitive single cell organisms
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virusus
not a living cell that can multiply only whithin living cell
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protozoa
single cell animals
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algae
very simple multi-cellular or single cell aquatic plants
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normal flora
microorganisms that live on or in the body
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anaerobic
bacteria that can grow in absence of oxygen
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aerobic
bacteria that requires oxygen
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facultative anaerobics
anaerobes that will use oxygen if it is present are able to grow whithout oxygen
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endospores
- bacteria that produce resistant forms that can tolerate long periods of dyness or other adverse conditions
- (all endospore-forming bacteria are bacilli)
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pili
help bacteria to glide along solid surfaces, can also help anchor bacteria to surfaces and to attach bacteria to each other for exchange of genetic information
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conjugation
bacteria attaching to each other for exchange of genetic information
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cocci
round cells in characteristic arrangements
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diplococci
- cells that are arranged in pairs; di- means two
- (gonorrhea, and meningitis)
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streptococci
- cells that are in chains: strept- means chain
- (pnuemonia)
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staphylococci
- cells arranged in clusters; staphylo- means cluster
- (pnuemonia)
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bacilli
- straight slender rods
- responsible for diphtheria, tetanus, tuberculosus
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vibrios
- short rods with a slight curvature like a comma
- (cholera)
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spirilla
long wavelike cells resembling a corkscrew
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spirochetes
- similar to spirilla but are capable of waving and twisting motion
- (syphilis)
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name the 3 shapes of bacteria
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prions
infectious particle composed solely of protein
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viroids
composed of rna alone with no protein coat
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micotic
- diseases caused by fungi
- ie. athletes foot, and ring worm
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candida
normal inhabitant of the mouth and digestive tract that may produce skin lesions, an oral infection called thrush, digestive upset, or inflamation of the vaginal tract(vaginitis)
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amoeba
an irregular mass of cytoplasm that propels itself by extending part of itself and then flowing into the extension
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sporozoa
cannot propel themselves, unable to grow outside of a host
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helminths
- parasites with human hosts
- (parasitic worms)
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iscaris
rounds worms---one of the most common infestations----affects the lungs or intestines. Long white/yellow worm pointed at both ends.
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trichina
small round worm found in pork and wild game
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flukes
leaf shaped flat worms
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sepsis
refers to the presence of pathogenic organismsor their toxins in the blood or tissue
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asepsis
condition in which no pathogens are present
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antibiotic
a substance produced by living cells that has the power to kill or arrest the growth of bacteria
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nosocomial
hospital accquired infections
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grams stain
most commonly used stain. negative is red; positive is bluish purple
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idio-
- self, seperate, distinct
- ie. self originating (unknown cause)
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septic
poison, rot, decay
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lesion
any wound or local damage to tissue
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erythema
redness of the skin
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macule
- a spot that is neither raise nor depressed,
- ie. measles or freckles
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papule
a firm raised area, as in some stages of chicken pox
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vesicle
a blister or small fluid filled sac as seen in chicken pox or shingles eruptions
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pustule
a vesicle filled with pus
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excoriation
a scratch into the skin
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laceration
a rough, jagged wound made by tearing of the skin
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ulcer
a sore associated with disintegration and death of tissue
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fissure
a crack in the skin
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keloids
excess collagen producing tumorlike masses or sharply raised areas on the skin surface
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dermatosis
a general term referring to any skin disease
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dermatitis
inflamation of the skin
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eczema
inflamation characterized by intense itching and skin inflamation
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psoriasis
a chronic overgrowth of the epidermis leading to large, sharply outlined, red, flat areas covered with silvery scales
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acne
a disease of the sebacceous glands connected with hair follicles
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impetigo
acute contagious disease of staphylococcal or streptoccal origin
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herpes simplex virus
- causes the formation of watery vesicles
- type I- causes lesions around the nose and mouth
- type II- responsible for genital infections
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shingles(herpes zoster)
caused by the same virus that causes chicken pox.
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verruca
- a small tumor caused by a virus of the human papillomavirus (hpv)
- means a wart
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pemphigus
- condition characterized by the formation of blisters in the skin and mucos membranes by autoimmune reactions
- fatal if not treated!
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lupus erythematosus
a chronic, inflammatory, autoimmune deasea of connective tissue
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scleroderma
desease of unknown that involves over production of colagen with thickening and tightening of the skin
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pressure ulcers
decubitus ulcer or bed sore which is a skin lesions that appears where the body rests on skin that covers boney projections
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sudoriferous
- sweat glands
- eccrin, and apocrine
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5 functions of the skin
- protection against infection
- protection against dehydration
- regulation of body temperature
- sensory information
- vitamin D
- absorption, excretion
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