the body’s specific protective
response to invading foreign agent or
organism
immunity
the study of diseases
that result from dysfunction of the
immune system
immunopathology
Major components of the Immune System
Bone marrow
WBC
Lymphoid tissues
Spleen
Lymph node
Tonsils
Adenoids
Thymus gland
Cells of the immune system
WBC
T cells
B cells
40-70% 0f WBC; circulating phagocytes
that are poised to respond quickly & in
vast #s where the tissue injury occurred
the first cells to arrive at the site; leave
vascular compartment & enter tissue
spaces searching out bacteria or cell
debris
Neutrophils
2-5% of WBCs; Phagocytic, but not as
effective as Neutrophils
are thought to protect humans against
parasitic worm infection e.g. pin worms,
tapeworms. Also, have a role in allergic
reactions
Eosinophils
0.2% of leukocytes. Functions in allergic
reactions.
Basophils
circulate in the blood; mature becomes
macrophages & migrate to tissues
literally means big eaters
responsible for removing antigens, damaged
cells, cellular debris by phagocytosis
Monocytes
originate from stem cells in the bone marrow
and mature into either T cells or B cells
Lymphocytes
B lymphocytes mature in the ___________
bone marrow
T lymphocytes mature in the
________ where they also differentiate into
cells with various functions
thymus
development of B lymphocytes
b lymphocytes > memory cells & plasma cells > plasma cells become anitbodies (HUMORAL RESPONSE)
development of T lymphocytes
Regulator T cells > helper T cells or suppressor T cells