Antidiabetics

  1. There are two groups of antidiabetic agents:
    insulin, oral hypoglycemic (antidiabetic) drugs
  2. protein secreted from the beta cells of the pancreas
    Insulin
  3. Insulin is necessary for
    • carbohydrate metabolism
    • protein and fat metabolism
  4. The beta cells make up ____ of the pancreas, and the alpha cells that secrete glucagon, a hyperglycemic substance, occupy approximately
    ____ of the pancreas.
    75%, 20%
  5. synthetic preparations that stimulate insulin release or otherwise alter the metabolic response to hyperglycemia
    Oral hypoglycemic drugs, also known as oral antidiabetic drugs
  6. Diabetes mellitus, a chronic disease resulting from deficient glucose metabolism, is caused by _________________________.
    insufficient insulin secretion from the beta cells
  7. Diabetes mellitus is characterized by the three p’s:
    • polyuria (increased urine output)
    • polydipsia (increased thirst)
    • polyphagia (increased hunger)
  8. ______________ is the most common type of diabetes.
    Type 2 diabetes mellitus
  9. Oral glucose load is more effective in raising the serum insulin level than an intravenous (IV) glucose load. True or False?
    True
  10. normal range for blood glucose
    60 to 100 mg/dL
  11. When the blood glucose level is greater than 180 mg/dL, ___________ (glucose in the urine) can occur.
    glycosuria
  12. Increased blood glucose acts as an osmotic diuretic, causing _______.
    polyuria
  13. For diagnostic purposes, an HbA1c level of ≤5% indicates that the patient does not have diabetes, 5.7% to 6.4% indicates prediabetes, and ≥6.5% indicates a diagnosis of diabetes mellitus.
  14. The beta cells in the pancreas secrete approximately ____________
    units/kg/day.
    0.2 to 0.5
  15. Insulins are usually administered ____________.
    subcutaneously (subQ)
Author
raine
ID
363725
Card Set
Antidiabetics
Description
Updated