What change is observed in leukocytes during an allergic disorder (type I hypersensitivity)
often caused by asthma, hay fever, and drug reactions?
B.
In infectious mononucleosis (IM), what does the Monospot test detect?
B.
Which description is consistent with acute lymphocytic leukemia (ALL)?
D.
Which description is consistent with chronic myelogenous leukemia (CML)?
C.
Which description is consistent with chronic lymphocytic leukemia (CLL)?
B.
Which electrolyte imbalance accompanies multiple myeloma (MM)?
D.
Reed-Sternberg (RS) cells represent malignant transformation and proliferation of which
of the following?
B.
Reed-Sternberg cells are the hallmark tumor cells of Hodgkin lymphoma.
Local signs and symptoms of Hodgkin disease–related lymphadenopathy are a result of
which of the following?
C.
Local symptoms caused by pressure and obstruction of the lymph nodes
Which virus is associated with Burkitt lymphoma in African children?
A.
Which term is used to describe a red-purple discoloration caused by diffuse hemorrhage
into the skin tissue?
A.
Which statement best describes heparin-induced thrombocytopenia (HIT)?
A.
Immune thrombocytopenia (ITP) is a(n) _____ condition in adults and a(n) _____
condition in children.
C.
Vitamin _____ is required for normal clotting factor synthesis by the _____.
C.
Vitamin K, a fat-soluble vitamin, is necessary for the synthesis and regulation of prothrombin, procoagulant factors (VII, IX, X), and anticoagulant regulators (proteins C and S) in the liver.
What is the most common cause of vitamin K deficiency?
C.
The most common cause of vitamin K deficiency is parenteral nutrition in combination
with broad-spectrum antibiotics that destroy normal gut flora.
Which disorder is described as an unregulated release of thrombin with subsequent fibrin
formation and accelerated fibrinolysis?
D.
DIC is an acquired clinical syndrome characterized by widespread activation of
coagulation resulting in the formation of fibrin clots in medium and small vessels throughout the body.
In disseminated intravascular coagulation (DIC), what activates the coagulation cascade?
C.
Direct tissue damage (ischemia and necrosis, surgical manipulation, crushing injury) causes the endothelium to release TF.
In disseminated intravascular coagulation (DIC), what are the indications of microvascular
thrombosis?
A.
What is the most reliable and specific test for diagnosing disseminated intravascular
coagulation (DIC)?
C.
What term is used to identify thrombi that occlude arterioles and capillaries and are made
up of platelets with minimal fibrin and erythrocytes?
B.
Which of the following is characterized by what is referred to as pathognomonic pentad of
symptoms?
C.
cWhich statement relates to immune thrombocytopenic purpura (ITP)?
C.
When the demand for mature neutrophils exceeds the supply, immature neutrophils are
released indicating:
B.
Premature release of the immature white blood cells is responsible for the phenomenon known as a shift to the left or leukemoid reaction.
Hodgkin disease is characterized by the presence of which of the following?
C.
Which classic clinical manifestation is not a symptom of Infectious Mononucleosis?
C.
Early detection of acute leukemia would exclude which of the following symptoms?
A.
What is not one of the most significant risk factors for the development of thrombus formation as referred to by the Virchow triad?
D.
The risk for developing spontaneous thrombi is related to several factors, referred to as the
Virchow triad: (1) injury to the blood vessel endothelium, (2) abnormalities of blood flow,
and (3) hypercoagulability of the blood.
Which statement is false regarding leukemia?
A.
In the leukemias, a single progenitor cell undergoes malignant transformation. The
common feature of all forms of leukemia is an uncontrolled proliferation of malignant
leukocytes, causing an overcrowding of bone marrow and decreased production and
function of normal hematopoietic cells.
The two major forms of leukemia, acute and chronic, are classified by which criteria?
(Select all that apply.)
a. Predominant cell type
b. Rate of progression
c. Age of individual when cells differentiation occurs
d. Stage of cell development when malignancy first occurs
e. Serum level of leukocytes
ANS: A, B
The current classification of leukemia is based on (1) the predominant cell of origin (either
myeloid or lymphoid) and (2) the rate of progression, which usually reflects the degree at
which cell differentiation was arrested when the cell became malignant (acute or chronic)
What is not a clinical manifestation of advanced non-African Burkitt lymphoma?
