Inserting bone marrow cells into an individual who produces abnormal erythrocytes is an
example of what type of therapy?
A.
DNA replication requires the enzyme DNA polymerase to:
a. Travel along the single DNA strand, adding the correct nucleotide to the new
strand
b. Move along the double strand of DNA to unwind the nucleotides of the double
helix
c. Hold the double strand apart while the correct nucleotides are added to the strand
d. Transport the double strand of DNA from the nucleus to the cytoplasm for protein
formation
a.
Transcription is best defined as a process by which:
C.
The purpose of a staining technique of chromosomes such as Giemsa is to:
A.
An amniocentesis indicates a neural tube defect when an increase in which protein is
evident?
D.
The most clinically useful technique for prenatal diagnosis of chromosomal abnormalities
at 3 months’ (12 weeks’) gestation is:
D.
The term for an error in which homologous chromosomes fail to separate during meiosis
or mitosis is:
D.
Which clinical manifestations would be expected for a child who has complete trisomy of
the twenty-first chromosome?
D.
What is the most common cause of Down syndrome?
A.
What syndrome, characterized by an absent homologous X chromosome with only a single
X chromosome, exhibits features that include a short stature, widely spaced nipples, and
webbed neck?
B.
A person with 47, XXY karyotype has the genetic disorder resulting in which syndrome?
D.
What is the chromosomal variation that causes Klinefelter syndrome?
D.
What is the second most commonly recognized genetic cause of mental retardation?
B.
Males are more often affected by which type of genetic disease?
B.
The presence of a zygote having one chromosome with the normal complement of genes
and one with a missing gene is characteristic of which genetic disorder?
A.
A child with which genetic disorder has a characteristic cry?
B. (cry of the cat)
The key to accurate DNA replication depends on which complementary base pairs? (Select
all that apply.)
a. Adenine with thymine
b. Adenine with guanine
c. Guanine with cytosine
d. Cytosine with thymine
e. Guanine with thymine
a, c
Examples of prenatal diagnostic studies include: (Select all that apply.)
a. Chorionic villus sampling (CVS)
b. Amniocentesis
c. Carrier screening
d. Preimplantation genetic diagnosis (PGD)
e. Drug-sensitivity testing
a, b, d.
Cystic fibrosis
autosomal recessive
A display of chromosomes ordered according to length and centromere location is called a _______________.
karyotype
A _______________ mutation of DNA involves addition or deletion of a number of base pairs that is not a multiple of three and thus alters all of the codons downstream from the site of insertion or deletion.
frameshift
Interchanging of genetic material between nonhomologous chromosomes is called _______________
translocation
Write the letters here in the correct order of the steps:
A. Translation
B. Transcription
C. mRNA leaves the nucleus
D. RNA polymerase binds to DNA promoter region
E. mRNA is spliced to remove noncoding sections
