What are the 2 processes of bone development in a fetus?
1.
2.
1.intramembranous ossification
2.endochondral ossification
A type of ossification that starts within embryonic connective tissue.
A. intramembranous ossification
What bones in the body develop through intramembranous ossification?
B. skull bones,part of the mandible, and clavicle
What do you call the location of the membrane where intramembranous ossification begins?
C. centers of ossification
Intramembranous ossification of the cranial bone membrane begins at approximately (1)_______ weeks of embryonic development and is completed at (2)_______ year of age.
C. 8 weeks: 2 years
How does centers of ossification function?
It expands to form new bone by gradually ossifying the membrane.
Thus the centers have the oldest bone, and the expanding edges contain the youngest bone.
The larger, membrane-covered spaces between the developing skull bones that have not yet been ossified is called the ___________.
fontanels or also called the soft spots
What is the first step in the intramembranous ossification?
A. Osteoblast activity
Osteoblast within the center of ossification begin producing bone matrix. Where the bone matrix surrounds the collagen fibers of the existing connective tissue membrane. During this process spongy bones are formed
What is the second step in the intramembranous ossification?
B. Spongy bone formation
After the development of the bone matrix, additional osteoblast gather around the surface of the trabeculae and produce more bone thereby making the trabeculae to become larger and longer.
Spongy bone forms as the trabeculae join together.
What is the third step in the intramembranous ossification?
C. Compact bone formation
Cells surrounding the developing bone (from the red bone marrow) specialize to form the periosteum (outer covering of the bone).
Osteoblast from the periosteum lay down bone matrix to form an outer surface of the compact bone.
What is the end product of the intramembranous ossification?
Bones with outer compact bone surface and spongy centers.