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Capillaria Philippinensis is also known as the causative agent fro what so - called disease?
Mystery disease, Pudoc disease or the human intestinal capillariasis
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Who discovered Capillaria P.?
N.P Salazar
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Where was Capillaria .P first discovered?
The first case was reported to be fro the town of Bacara in Ilocos Norte in 1963
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Describe the morphology of Capillaria P. ova.
It has a moderately thick striated egg sheath with flattened bipolar plugs
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Capillaria ova shape
elipse
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Capillaria ova plugs
Bipolar not protuberant, unlike t. trichuiria
Protuberant - bulging
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Capillaria ova shell.
Pitted
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The diagnostic stage of capilliara p.
Ova
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What is the life cycle of Capillaria P.?
- 1. Unembryonated eggs are passed in the human/ bird stool.
- 2.Unembryonated eggs become embryonated in the external environment.
- 3.Fresh water fish ingest embyonated egg, larvae hatch, penetrate the intestine, migrate to tissues.
- 4.Ingestion of raw or undercooked fish results in infection of human host.
- 5.Adult worms reside in human small intestine, burrow in the mucusa.
- 6. Female adult worm deposit unembryonated egg.
- * Some eggs become embryonated in the intestine, release larvae, and may cause autoinfection, leading to hyperinfetion.
- 7. Parasite of fish- eating birds (eat the small fish)
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What organism acts as the intermediate host of Capillaria P.?
Fresh water fish
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What disease may result from infection of capillaria?
- ☊Intestinal Capillariasis
- ☊Damage cells of intestinal wall (because worms repeatedly penetrate the mucosa of the small intestine and re enter the jejunum)
- ☊It may interfere with the absorption of nutrients and maintenance of proper electrolyte.
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Give at least 3 symptoms of intestinal capilliarasis.
- ☊watery diarrhea
- ☊abdominal pain
- ☊edema
- ☊weight loss
- ☊weakness
- ☊malaise
- ☊anorexia
- ☊emaciation
- ☊stomach growling
- ☊depressed levels of potassium and albumin in blood
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What area of the body does the worms usually penetrate and invade?
Mucosa of the small intestine.
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How can Capilliara p. be diagnosed?
Stool samples can detect une,bryonated egg, larvae and adult especially on severe infections.
Intestinal biopsies
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If left untreated infection of capilliara may be _____.
Patients die from
1.
2.
3.
fatal
- 1.loss of electrolyte
- 2.heart failure
- 3.secondary bacterial infections
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Medicines that could be taken to treat capilliara infection?
- 1.Albendazole 400 mg once daily for 10 days
- 2.Mebendazole 200 mg once daily for 20 days
Relapse may occur if the treatment regimen is not followed.
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Common name for capillaria philippinensis
pudoc worm
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