Respiratory pathology

  1. COPD
    • chronic inflammation of the lungs
    • emphysema: barrel chest, SOB, wheeze, clubbing, fatigue, resp acidosis, freq resp infections, productive cough

    chronic bronchitis: bronchi become inflamed/scarred, similar ss

    • TX: breathing tx, venturi mask (allows for O2 adjust)
    • NRB nor recommended.  Respiratory drive from O2-not CO2.  keep them 88-90%
  2. Asthma
    • allergic reaction  IgE
    • early-histamines, prostaglandins, leukocytes released
    • permeability-->mucus-->obstruction

    late (24-48 hours) inflammation-->hypoxia.  CO2 trapping-->RAAS activation

    • status asthmaticus: distress refractory to meds
    • test; FEV1-forced exp. volume (L/sec). an increase of 12% with bronchodilator=asthma
    • PEAK FLOW-  80-100% green  50-79% yellow (inhaler), <50 red (emergent)

    • Tx: bronchodilators=relievers, B agonists, anticholinergics. short-acting
    • CONTROLERS-corticosteroids, theophyline (stimulant-take w/food).    Long lasting

    • Combinations.  still need Rx inhaler handy
    • antitussives (work on medulla oblongata)
  3. Cystic fibrosis
    • Progressive genetic disease
    • Build up of mucus in the lungs-->infection-->damage-->failure

    SS: cough, infections, wheezing, poor growth, greasy turds, salty sweat

    Diagnostic: sweat-chloride test, GI enzyme

    Tx: mucolytics, bronchodilators, antibiotics, pancreatic enzyme supplements, CFTR modulator therapy (target malfunction protein)
  4. Sinusitis
    Inflammation of nose/sinus- increased when lean forward

    • Acute= 1 month or less
    • Chronic=more

    Tx spray, decongestants, px meds, H1 antagonist, Sx (Caldwell-Luke)
  5. Pneumonia
    Community, Hospital, or respirator-acquired
    • complication that results from infection
    • PH ↓  leads to acute kidney damage

    exudates fill alveoli-->impairs O2/CO2 exchange

    ss: fever, tachypnea, dyspnea, chills, cough, CP, fatigue, myalgia (muscle px), arthralgia (joint px)

    LABS WBCs (30-300), ABGs, sputum cultures w/ gram stain
  6. Pulmonary Embolism
    • End result of DVT
    • ss tachypnea, hypoxia, pleuritic CP, collapse to floor, fever
    • test chest xray (wont show up for 24 hrs), angiogram, ABGs

    Tx O2, cough, ROM exercises
Author
safado
ID
361794
Card Set
Respiratory pathology
Description
Updated