Module 8: Sporozoans (Toxoplasma gondii)

  1. Toxoplasma gondii can cause ____________
    Toxoplasmosis
  2. (Toxoplasma gondii) ______ are definitive host; excrete organism in feces
    Cats
  3. (Toxoplasma gondii) For immunosuppressed patient with focal neurologic signs, ________________ is the most likely diagnosis.
    cerebral toxoplasmosis
  4. (Toxoplasma gondii) ____________, the disease of which T. gondii is the
    causative agent is usually minor and self-limiting but can have serious or even fatal effects on a fetus whose mother first contracts the disease
    during pregnancy or on an immunocompromised human or cat (definitive host).
    Toxoplasmosis
  5. (Toxoplasma gondii) Form that is present in cat and other felines but not in humans
    Oocyst
  6. (Toxoplasma gondii) shape of oocyst
    oval or spherical shape and contains sporoblast
  7. (Toxoplasma gondii) Oocyst is formed by ___________ reproduction
    sexual (Gametogony)
  8. (Toxoplasma gondii Morphology) (tachos = speed in Greek) was coined by __________ to describe the stage that rapidly multiplied in any cell of the intermediate host and in nonintestinal epithelial cells of the definitive host.
    Frenkel
  9. (Toxoplasma gondii Morphology) The term “___________” replaces the previously used term “trophozoite” (trophicos = feeding in Greek).
    tachyzoite
  10. (Toxoplasma gondii) Tachyzoite is _________ shaped
    crescent
  11. (Toxoplasma gondii Morphology) these are trophozoites released which infects other cells
    Tachyzoite
  12. (Toxoplasma gondii Morphology) occurs in chronic infection; formed when parasites multiply and produce a wall within host cell
    Tissue cyst
  13. (Toxoplasma gondii Morphology) __________ are slowly multiplying forms of trophozoite contained in a tissue cyst
    Bradyzoites
  14. (Toxoplasma gondii) Serologic prevalence data indicate that _____________ is one of the most common of human infections throughout the world.
    toxoplasmosis
  15. (Toxoplasma gondii) T. gondii is important because virtually all warm-blooded animals, including man, can become infected with it. True or False?
    True
  16. (Toxoplasma gondii) Cats have a 20% to 40% infection rate with T. gondii. True or False?
    False.

    20% to 60%
  17. (Toxoplasma gondii) In an older cat, a recurrent infection may be due to the presence of ________________ or feline immunodeficiency virus, which suppress its immune response.
    feline leukemia virus
  18. (Toxoplasma gondii) Mostly asymptomatic infection, but new infection in pregnancy causes _________________; also infection in immuno-suppressed.
    fetal malformations
  19. (Toxoplasma gondii) Transmission
    By poorly cooked meat, from cat stool, rarely water
  20. (Toxoplasma gondii) Detection
    Serology
  21. (Toxoplasma gondii) symptoms
    • -anorexia, weight loss, lethargy, difficulty breathing (because of pneumonia), eye inflammation, and fever
    • -vomiting and diarrhea, neurological symptoms, swollen lymph nodes,
    • and jaundice.
  22. (Toxoplasma gondii) Contact with a pet cat or a neighbor's cat will not
    increase the risk of acquiring toxoplasmosis, unless these animals are allowed to roam and hunt or eat raw meat. However, contact with stray
    and feral cats can be risky. True or False?
    True
  23. (Toxoplasma gondii) T. gondii infections have the ability to change the
    behavior of rats and mice, making them drawn to, rather than fearful of, the scent of cats. True or False?
    True
  24. (Toxoplasmosis) Infected women were more likely to become more
    outgoing and showed signs of higher intelligence, while men became aggressive, jealous and suspicious. True or False?
    True
  25. (Toxoplasmosis Diagnosis) Specimen
    • 1. Lymph node biopsy
    • 2. Bone marrow aspiration
    • 3. CSF
    • 4. Broncho alveolar lavage
    • 5. Peritoneal fluid
  26. (Toxoplasmosis Diagnosis) Lab procedures
    • 1. Direct microscopy (Leishman/Giemsa Stain) - Findings: Tachyzoite
    • 2. Culture (Bradyzoite is observed)
  27. (Toxoplasmosis Diagnosis) _______________ may indicate recent infection with T. gondii, but not a definitive diagnosis of toxoplasmosis.
    Blood serology tests
  28. (Toxoplasmosis) Treatment
    • -Triple Therapy
    • -Sulfadiazine / Pyrimethamine / Corticosteroids
  29. (Toxoplasma gondii) The most notable manifestation of toxoplasmosis in
    immunocompromised patients is _________________, which can be deadly.
    toxoplasmic encephalitis
  30. (Toxoplasma gondii) If infection with T. gondii occurs for the first time
    during pregnancy, the parasite can cross the placenta, possibly leading to hydrocephalus or microcephaly, intracranial calcification, and chorioretinitis, with the possibility of spontaneous abortion (miscarriage) or intrauterine death.
    additional information
Author
raine
ID
361510
Card Set
Module 8: Sporozoans (Toxoplasma gondii)
Description
Updated