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What are the 3 major types of inflammatory bowel diseases that cause chronic idiopathic intestinal inflammation and can cause oral manifestations like ulcers etc...
- 1. Ulcerative colitis (UC)
- 2. Crohn's disease (CD)
- 3. Indeterminate colitis
Can be caused by a combination of environmental triggers, genetic suceptibility (see in twins) and immune dysregulation (reaction to luminal bacteria)
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In ulcerative colitis, which layer is affected in the rectum and length of colon
- Mucosal layer, presented continuously though colon
- Causes diarrhea, pain, rectal bleeding etc..
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In chron's disease, which layers are affected?
Transmural layers and affects the colon segmentally
- Can involve any site from mouth to anus
- Causes fever, vomiting, weight loss, diarrhea, abdominal abscess
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Oral manifestations of IBD
- Asymmetric lip swelling
- gingival hyperplasia
- Granulomatous inflammation on biopsies
- Linear ulcerations
- Cobblestoning
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