-
It consists of structures use to acquire oxygen and remove carbon dioxide from the blood.
Respiratory system
-
It is required for the body's cells to synthesize the chemical energy molecule, ATP.
Oxygen
-
It is a by-product of ATP production and must be removed from the blood.
Carbon Dioxide
-
What happens if there are increased levels of carbon dioxide (CO2) in the blood?
The pH of the blood lowers
-
What are the 7 structures that make up the respiratory system?
- 1. External nose
- 2. Nasal cavity
- 3. Pharynx
- 4. Larynx
- 5. Trachea
- 6. Bronchi
- 7. Lungs
-
It encloses the chamber for inspired air.
External nose
-
It is a cleaning, warming, and humidifying chamber for inspired air.
Nasal cavity
-
The pharynx is commonly called the?
Throat
-
It serves as a shared passageway for food and air.
Pharynx
-
The larynx is frequently called the?
Voice box
-
Its rigid structure helps keep the air constantly open, or patent.
Larynx
-
The trachea is commonly called the?
Windpipe
-
It serves as an air-cleaning tube to funnel inspired air in each lung.
Trachea
-
These are tubes that direct air into the lungs.
Bronchi
-
Each ____ is a labyrinth of air tubes and a complex network of air sacs, called alveoli, and capillaries.
Lung
-
What are the two broad aspects of respiration?
- - Ventilation
- - Respiration
-
It is simply the movement of air into and out of the lungs.
Ventilation
-
It is the diffusion of gases across cell membranes.
Respiration
-
What are the two types of respiration within the body?
- - External respiration
- - Internal respiration
-
It is the movement of gases between atmospheric air in the lungs and blood.
External respiration
-
It is the movement of gases between the blood and the body's cells.
Internal respiration
-
The respiratory tract is separated into two regions. What are these?
- - Upper respiratory tract
- - Lower respiratory tract
-
It includes structures from the nose to the larynx.
Upper respiratory tract
-
It includes structures from the trachea through the alveoli in the lungs.
Lower respiratory tract
-
It encompasses the structures from the nose to the smallest air tubes within the lungs and is strictly for ventilation.
Conducting zone
-
It is solely within the lungs and includes some specialized small air tubes and the alveoli.
Respiratory zone
-
What are the four simultaneous process that occur for gas exchange to happen?
- - Ventilation
- - External respiration
- - Gas transport
- - Internal respiration
-
It consists of the external nose and the nasal cavity.
Nose
-
It is the visible structure that forms a prominent feature of the face.
External nose
-
It is the open chair inside the nose where air first enters the respiratory system.
Nasal cavity
-
These are the anterior external openings of the nasal cavity.
Nares or nostrils
-
Posterior openings of the nasal cavity to the pharynx
Choanae
-
The floor of the nasal cavity, which separates it from the oral cavity in the mouth.
Hard palate
-
A wall of tissue that separates the nasal cavity into right and left halves.
Nasal septum
-
It occurs when a septum bulges to one side and is a common cause of snoring.
Deviated septum
-
These are three lateral bony ridges on each side of the nasal cavity.
Conchae
-
These are openings within the superior and middle meatuses.
Paranasal sinuses
-
It is an opening for tear drainage from the surface of the eye.
Nasolacrimal duct
-
It is the inflammation of the mucous membrane of a sinus, especially one or more of the paranasal sinuses.
Sinusitis
-
What are the five functions of the nasal cavity?
- 1. Serves as a passageway for air.
- 2. Cleans the air.
- 3. Humidifies and warms the air.
- 4. Contains the olfactory epithelium.
- 5. Helps determine voice sound.
-
What are the two sources of moisture in the nasal cavity?
- - mucous epithelium
- - tears that drain into the nasal cavity through the nasolacrimal duct
-
It is the common opening of both the digestive and respiratory systems.
Pharynx
-
The pharynx is connected to the respiratory system at the?
Larynx
-
The pharynx is connected to the digestive system at the?
esophagus
-
What are the three regions of the pharynx?
- 1. Nasopharynx
- 2. Oropharynx
- 3. Laryngopharynx
-
It is the most superior portion of the pharynx.
Nasopharynx
-
It is an incomplete partition composed of muscle and connective tissue, and separates the nasopharynx from the middle portion of the pharynx.
Soft palate
-
It is the extension of the soft palate.
Uvula
-
The posterior wall of the nasopharynx houses the?
Pharyngeal tonsil
-
It is a continuation of the nasopharynx.
Oropharynx
-
It is the middle portion of the pharynx and is posterior to the mouth and begins at the soft palate.
Oropharynx
-
It is a continuation of the oropharynx.
Laryngopharynx
-
It spans the posterior length of the pharynx.
Laryngopharynx
-
It is located in the anterior part of the laryngopharynx and extends from the base of the tongue to the trachea.
Larynx
-
Why is the larynx rigid?
Because of the nine cartilages connected to one another
-
What are the cartilages composing the larynx?
- - Thyroid cartilage
- - Cricoid cartilage
- - Epiglottis
- - Arytenoid Cartilage
- - Corniculate cartilage
- - Cuneiform cartilage
-
It is the largest of the cartilages, and is a single-shaped piece called the adam's apple.
Thyroid cartilage
-
It forms the base of the larynx and is a single piece of cartilage upon which other cartilages rest.
Cricoid cartilage
-
It is a single piece of cartilage that is attached to the thyroid cartilage and projects superiorly.
Epiglottis
-
These paired cartilages articulate with the superior border on the posterior of the cricoid cartilage.
Arytenoid cartilages
-
These are paired cartilages that are attached to the superior tips of the arytenoid cartilages.
Corniculate cartilages
-
These are paired cartilages that are contained in a mucous membrane anterior to the corniculate cartilages.
Cuneiform cartilages
-
What are the ligaments used for speech?
- - vestibular folds
- - vocal folds
-
These are known as the false vocal chords and are the superior pair of ligaments.
Vestibular folds
-
These are known as the true vocal chords and are the inferior ligaments.
Vocal folds
-
It occurs when the vocal folds become inflamed and the person "loses" his or her voice.
Laryngitis
-
These are the primary source of sound production.
Vocal folds
-
The force of air moving past the vocal folds determines the?
Loudness of the sound
-
The frequency of vibrations of the air moving pas the vocal folds determines the?
Pitch
-
It allows the air to flow into the lungs.
Trachea
-
The trachea is reinforced with how many C-shaped pieces of cartilages?
15-20
-
What are the reinforced cartilages in the trachea called?
Tracheal rings
-
These support the trachea and prevent it from collapsing.
Tracheal rings
-
The trachea has an inside diameter or?
12 mm
-
The trachea has a length of?
10-12 cm
-
The trachea descends from the larynx to the?
Fifth thoracic vertebra
-
The trachea divides to form two smaller tubes called?
Main bronchi
-
At the location of where the trachea divides into the two main bronchi is a ridge of cartilage called the?
Carina
-
It consists of the trachea and the network of air tubes in the lungs.
Tracheobronchial tree
-
What main bronchus is larger in the diameter and more in line with the trachea?
Right main bronchus
-
How many levels of branching occur from the trachea to the smallest air tubes?
16 levels
-
What are the four classes of air passageways?
- 1. Lobar bronchi
- 2. Segmental bronchi
- 3. Bronchioles
- 4. Terminal bronchioles
-
These are also known as the secondary bronchi, and arise directly from the main bronchi.
Lobar bronchi
-
How many lobar bronchi are in the left and right lung?
- Left lung - 2
- Right lung - 3
-
These are also called the tertiary bronchi, and supply subdivisions within each lung lobe, which are called bronchopulmonary segments.
Segmental bronchi
-
These result from the continued branching of the segmental bronchi.
Bronchioles
-
These arise from several subdivisions of bronchioles.
Terminal bronchioles
-
It occurs when the smooth muscle relaxes, making the bronchiole diameter large.
Bronchodilation
-
It occurs when the smooth muscle contracts, making the bronchiole diameter smaller.
Bronchoconstriction
-
What helps counteract the effects of an asthma attack by promoting smooth muscle relaxation in the walls of terminal bronchioles?
Albuterol
-
These are small, air-filled chambers where the air and blood come into close contact with each other.
Alveoli
-
What are the multiple levels of branching from the terminal bronchioles to the alveoli?
- 1. Respiratory bronchioles
- 2. Alveolar ducts
- 3. Alveolar sacs
-
How many alveoli are approximately in the lungs?
300 million alveoli
-
What is the average diameter of an alveolus?
250 um (micrometer)
-
The alveolar walls and the surrounding pulmonary capillaries form the?
Respiratory membrane
-
The thoracic wall consists of the?
- - thoracic vertebrae
- - ribs
- - costal cartilages
- - sternum
- - associated muscles
-
It is the space enclosed by the thoracic wall and the diaphragm.
Thoracic cavity
-
It is a sheet of skeletal muscle separating the thoracic cavity from the abdominal cavity.
Diaphragm
-
These are the primary organs for respiration.
Lungs
-
These are among the largest organs of the body.
Lungs
-
The portion of the lung in contact with the diaphragm is the?
base
-
The portion of the lungs that extends above the clavicle is the?
apex
-
Which is larger? The right or left lung?
Right lung
-
How much does the right lung weigh?
620 g
-
How much does the left lung weigh?
560 g
-
It is an indentation on the medial surface of the lung.
Hilum
-
All structures passing through the hilum are referred to as the?
root of the lung
-
The lung lobes are separated by deep, prominent _____ on the surface of the lung.
Fissures
-
The left lung also has a medial indentation called the?
Cardiac notch
-
The lung lobes are further subdivided into?
Bronchopulmonary segments
-
How many bronchopulmonary segments are in the left lung? In the right lung?
-
The bronchopulmonary segments are further divided into?
Lobules
-
Blood that has passed through the lungs and picked up O2 is called?
Oxygenated blood
-
Blood that has passed through the tissues and released some of its O2 is called?
Deoxygenated blood
-
What are the two blood flow routes to the lungs?
- 1. Blood flow to the alveoli
- 2. Blood flow to the tissues of the bronchial tree
-
The lungs have two lymphatic supplies. What are these?
- - Superficial lymphatic vessels
- - Deep lymphatic vessels
-
This pleural cavity covers the inner thoracic wall, the superior surface of the diaphragm, and the mediastinum
Parietal pleura
-
This pleural cavity covers the surface of the lung.
Visceral pleura
-
What are the two primary aspects to ventilation?
- 1. actions of the muscles of respiration
- 2. air pressure gradients
-
What are the muscles of inspiration?
- 1. diaphragm
- 2. external intercostals
- 3. pectoralis minor
- 4. scalene muscles
-
These act to increase the volume of the thoracic cavity.
Muscles of inspiration
-
These muscles decrease the thoracic volume by depressing the ribs and the sternum.
Muscles of expiration
-
What are the muscles of expiration?
- 1. internal intercostals
- 2. transverse thoracis
-
It is a flat sheet of connective tissue at the top of the dome.
Central tendon
-
Upon inspiration, the air pressure within the thoracic cavity _____.
decreases
-
Upon expiration, the air pressure within the thoracic cavity _____.
increases
-
It is the process of measuring volumes of air that move into and out of the respiratory system.
Spirometry
-
It is the device used to measure pulmonary volumes.
Spirometer
-
What are the four different volumes measured in spirometry?
- 1. tidal volume
- 2. expiratory reserve volume
- 3 residual volume
- 4. inspiratory reserve volume
-
These are the sum of two or more pulmonary volumes.
Pulmonary capacities
-
Formula for inspiratory capacity
Tidal volume + Inspiratory reserve volume
-
It is the amount of air a person can inspire maximally after a normal expiration.
Inspiratory capacity
-
Vital capacity formula
Inspiratory reserve volume + Tidal volume + Expiratory reserve volume
-
It is the maximum volume of air a person can expel from the respiratory tract after a maximum inspiration.
Vital capacity
-
Functional residual capacity formula
expiratory reserve volume + residual volume
-
It is the amount of air remaining in the lungs at the end of a normal expiration.
Functional residual capacity
-
Total lung capacity formula
tidal volume + expiratory + inspiratory reserve volume + residual volume
-
It is a functional measure of lung performance
Forced vital capacity
-
It is the measure of the volume of air available for gas exchange per minute.
Alveolar ventilation
-
The remaining areas where no gas exchange occurs
Dead space
-
What are the two types of dead space?
- - Anatomical dead space
- - Physiological dead space
-
A dead space that inlcludes all the structures of the upper respiratory tract, and structures of the lower respiratory tract to the terminal bronchioles.
Anatomical dead space
-
A dead space that is the combination of the anatomical dead space and the volume of any alveoli with lower than normal gas exchange.
Physiological dead space
-
It is the individual pressure of each gas.
Partial pressure
-
How can you determine the partial pressure of each gas?
Percentage of the gas multiplied by the total pressure (760 mm Hg)
-
What are the two factors that influence the ability of alveoli to increase and decrease in volume?
- - lung recoil
- - pleural pressure
-
It is the tendency for the lungs to decrease in size after they are stretched.
Lung recoil
-
Lung recoil occurs for two reasons. What are these?
- - elastic recoil
- - surface tension
-
It occurs because elastic fibers within the lungs and thoracic wall return to their original shape and size once the tension on them is released.
Lung recoil
-
This occurs because of hydrogen bonding within the alveoli.
Surface tension
-
Collapse of the alveoli due to the surface tension is prevented by the molecule?
Surfactant
-
It is a mixture of lipoprotein molecules produced by the surfactant-secreting cells of the alveolar epithelium
Surfactant
-
It is the pressure within the pleural cavity between the parietal pleura and the visceral pleura
Pleural pressure
-
If pleural pressure is increased, what happens?
Lungs collapse
-
If there is lower pressure outside the lungs during inspiration, what happens?
Alveoli expand
-
The increase in pleural pressure is called?
Pneumothorax
-
What are the two major possible causes of pneumothorax?
- - Penetrating trauma
- - Nonpenetrating trauma
-
Being stabbed, getting shot by a gun, breaking a rib
Types of penetrating traumas
-
Blow to the chest; a medical procedure
Types of nonpenetrating trauma
-
In this kind of pneumothorax, the pressure within the pleural cavity is always higher than the barometric air pressure.
Tension pneumothorax
-
What are the three major factors that influence the rate of gas diffusion through the respiratory membrane?
- 1. partial pressure gradients for O2 and CO2
- 2. thickness of the respiratory membrane
- 3. surface area of the respiratory membrane
-
What is the partial pressure gradient for O2?
Alveoli - blood - body's cells
-
What is the partial pressure gradient for CO2?
Body's cells - blood - alveoli
-
The thicker the respiratory membrane, the (higher or lower) the gas diffusion.
Lower
-
It is the most common cause of increased respiratory membrane thickness; is an accumulation of fluid in the alveoli
Pulmonary edema
-
The lower the surface area, the (higher of lower) rate of gas diffusion.
Lower
-
In a healthy adult, the total surface area of the respiratory membrane is approximately?
70
-
It is a complex protein synthesized by immature red blood cells
Hemoglobin
-
It consists of four subunits, each containing one iron-based heme goup
Hemoglobin
-
This is where O2 binds, so one hemoglobin can carry up to four O2 molecules
Heme group
-
An altered form of hemoglobin can be found in individuals with?
Sickle-cell disease
-
How many percent of oxygen is transported bound to hemoglobin?
98.5%
-
How many percent of oxygen is transported dissolved in plasma?
1.5%
-
It is formed as a by-product of the breakdown of glucose when cells use O2 to produce ATP.
Carbon dioxide
-
What are the three ways CO2 is transported in the blood?
- 1. dissolved in plasma
- 2. bound to hemoglobin
- 3. converted to bicarbonate ion
-
How many percent of CO2 is dissolved directly in plasma?
7%
-
How many percent of CO2 is bound to hemoglobin?
23%
-
How many percent of CO2 is converted to bicarbonate ions?
70%
-
It is an enzyme that catalyzes the production of carbonic acid from CO2 and H2O
Carbonic anhydrase
-
What controls the respiratory rate?
Medulla oblongata
-
The medullary respiratory center has two sets of neurons. What are these?
- - dorsal respiratory group
- - ventral respiratory group
-
It is a collection of neurons that are most active during inspiration.
Dorsal respiratory group
-
It is a collection of neurons that are active during both inspiration and respiration.
Ventral respiratory group
-
What establishes the basic rhythm of respiration?
pre-Botzinger complex
-
It is a collection of neurons in the pons that help regulate respiration rate.
Pontine respiratory group
-
A decrease in O2 below its normal values is called?
Hypoxia
-
High PO2 =?
Low respiratory rate
-
Low PO2 =?
High respiratory rate
-
Low PCO2 =?
Low ventilation
-
High PCO2 =?
High ventilation
-
A greater-than-normal amount of CO2 in the blood?
Hypercapnia
-
Lower than normal CO2 level in the blood?
Hypocapnia
-
It limits the depth of inspiration and prevents overinflation of the lungs.
Hering-Breuer reflex
-
The highest level of exercise that can be performed without causing a significant change in the blood pH
Anaerobic threshold
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