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A small gland about the size of a pea and is housed in a depression of the sphenoid bone inferior to the hypothalamus of the brain
Pituitary gland
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Serves as the control center for the autonomic nervous system as well as the endocrine system
Hypothalamus
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The pituitary gland is divided into 2 parts
- Anterior Pituitary
- Posterior Pituitary
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Made up of epithelial cells derived from the embryonic oral cavity
Anterior Pituitary
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Is an extension of the brain and is composed of neurons
Posterior Pituitary
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Historically the pituitary gland was known as the?
The body’s master gland
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The hypothalamus controls the pituitary gland in two ways
- Hormonal control
- Direct innervation
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Synthesizes hormones, whose secretion is under the control of the hypothalamus
Anterior pituitary gland
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The storage location for two hormones synthesized by special neurons in the hypothalamus
Posterior pituitary gland
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Hormones secreted from the anterior pituitary are?
Proteins
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Many hormones from the anterior pituitary gland are?
Tropic hormones
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These hormones stimulate the secretion of other hormones from the target tissues
Tropic hormones
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Hormone that stimulates the growth of bones, muscles, and other organs by increasing gene expression.
Growth Hormone
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Hormones that slows protein breakdown during periods of food deprivation and favors lipid breakdown
Growth Hormone
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A young person suffering from a deficiency of growth hormone remains small, although normally proportioned, and is called a
Pituitary dwarf
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Excess growth hormone secretion is the result from?
Hormone-secreting tumors of the pituitary gland
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Hormone-secreting tumors of the pituitary glands will lead to
Excess growth hormone secretion
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The person becomes abnormally tall and the condition is called?
Giantism
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Facial features and hands become abnormally large, and the condition is called?
Acromegaly
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The secretion of growth hormone is controlled by two hormones from the hypothalamus which are?
- Releasing hormone
- Inhibiting hormone
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This hormone stimulates growth hormone secretion
Releasing hormone
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This hormone inhibits its secretion
Inhibiting hormone
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Part of the effect of growth hormone is influenced by a group of protein hormones called?
Insulin-like growth factors (IGFs) or somatomedins
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Another name for insulin-like growth factors
Somatomedins
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Hormone that binds to membrane-bound receptors on cells of the thyroid gland and stimulates the secretion of thyroid hormone. Can also stimulate the growth of thyroid gland.
Thyroid-Stimulating Hormone
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The rate of TSH secretion is regulated by what hormone from the hypothalamus
Releasing hormone
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Hormone that binds to membrane-bound receptors on cells of the adrenal cortex
Adrenocorticotropic Hormone
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ACTH increases the secretion of a hormone from the adrenal cortex called?
Cortisol
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Another name for cortisol
Hydrocortisone
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ACTH molecules bind to where?
ACTH molecules bind to the melanocytes of the skin and increase pigmentation.
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Too much ACTH secretion will lead to what?
Darkening of the skin
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The rate of the ACTH is INCREASED by what hormone from the hypothalamus?
Releasing hormone
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Hormone that binds to membrane-bound receptors on the cells of the gonads
Gonadotropin
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What are gonads?
Ovaries and testes
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Hormone that regulate the growth, development, and functions of the gonads
Gonadotropin
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What are the two major gonadotropins
- Luteinizing hormone
- Follicle-stimulating hormone
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In females, this hormone stimulates ovulation
Luteinizing hormone
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In females, this hormone promotes the secretion of reproductive hormones, estrogen and progesterone
Luteinizing hormone
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In males, this hormone stimulates to secrete the reproductive hormone, testosterone
Luteinizing hormone
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In females, this hormone stimulates the development of follicles in the ovaries
Follicle-stimulating hormone
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In males, this hormone stimulates the development of sperm cells in the testes
Follicle-stimulating hormone
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The secretion of both LH and FSH is increased by what hormone from the hypothalamus?
Releasing hormone
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This hormone binds to membrane-bound receptors in cells of the breast
Prolactin
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This hormone helps promote development of the breast during pregnancy and stimulates the production of milk following pregnancy
Prolactin
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This is formerly called prolactin-inhibiting hormone
Dopamine
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Hormone that binds to membrane-bound receptors on melanocytes and causes them to synthesize melanin
Melanocyte-Stimulating Hormone
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Melanocyte-Stimulating Hormone synthesize what?
Melanin
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Oversecretion of Melanocyte-Stimulating Hormone will lead to?
Darkening of the skin
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Melanocyte-Stimulating Hormone has two regulatory hormones from the hypothalamus which are:
- One that increases MSH secretion
- One that decreases MSH secretion
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Hormone that binds to membrane-bound receptors and increases water reabsorption by kidney tubules.
Antidiuretic Hormone
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Antidiuretic Hormone is also called
Vasopressin
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What is the result of reduced ADH release
Results in large amounts of dilute urine
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Lack of ADH secretion causes?
Diabetes Insipidus
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A condition where there is production of a large amount of dilute urine
Diabetes Insipidus
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Hormone that binds to membrane-bound receptors and causes contraction of the smooth muscle cells of the uterus as well as milk letdown from the breasts in lactating women
Oxytocin
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Commercial preparations of oxytocin is given to assist in childbirth and constrict uterine blood vessels following childbirth
Pitocin
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