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Resting membrane potentials and action potentials occur in neurons
True
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2 types of membrane channels
- 1. Leak channels
- 2. Gated channels
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Channels that are always open; Ions can "leak" across the membrane down their concentration gradient
Leak channels
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Channels that are generally closed, but can be opened due to voltage or chemical
Gated channels
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Channels that can be opened by neurotransmitters
Chemically gated channels
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Channels that can be opened by a change in membrane potential
Voltage-gated channels
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Maintains resting levels of ions across the cell membrane
Sodium-potassium pump
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The sodium-potassium pump actively transports ___ into the cell and ___ out of the cell
K+, Na+
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The sodium-potassium pump consumes ___ of all the ATP in a typical cell and ___ of the ATP in a neuron
25%, 70%
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Changes in response to stimuli
Resting membrane potential of a neuron
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Allow conductivity along nerve or muscle membrane, similar to electricity going along an electrical wire
Action potentials
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Is generated primarily by the uneven distribution of K+, Na+, and negatively charged proteins across the cell membrane
Resting membrane potential
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In neurons, there are ______ more K+ leak channels than Na+ leak channels in the cell membrane
50-100 times
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Movement of Na+, called a ____, causes the inside of the cell membrane to become positive, a change called _____.
Local current, depolarization
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What constitutes an action potential?
Depolarization and repolarization
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Action potentials are conducted slowly in myelinated axons and more rapidly in unmyelinated axons
False
Action potentials are conducted slowly in unmyelinated axons and more rapidly in myelinated axons
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Is a junction where the axon of one neuron interacts with another neuron or with cells of an effector organ, such as a muscle or a gland
Synapse
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3 Major components of a synapse
- 1. Presynaptic terminal
- 2. Postsynaptic membrane
- 3. Synaptic cleft
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Diffuse across the synaptic cleft and bind to specific receptor molecules on the postsynaptic membrane
Neurotransmitters
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Best known neurotransmitters
Acetylcholine and Norepinephrine
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Enzyme that breaks down the acetylcholine
Acetylcholinesterase
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