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Ventilation
Process of moving air in and out of lungs
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What are the two gases that diffuse over the alveolar-capillary (fantastically)
Oxygen and Carbon dioxide
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Describe the process of moving air in and out of the lungs
First- alveolar Capillary membrane diffuses gases
Second -the gases go to our lungs
Third- oxygen leaves our lungs
Four -oxygen goes into our blood
Five -Carbon dioxide leaves blood
Six -Blood goes to the lungs
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Partial Pressures of Gas
Air
–Oxygen (21 * 760) = 159mmHg
–Nitrogen (79 * 760) = 597
–Argon
–Carbon dioxide
–Others…
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Combined pressures
atmospheric pressures
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atmospheric pressures
760 mmHg combined pressures
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Dalton’s Law
The pressure of each gas in a mixture exerts a partial pressure proportional to its fractional percentage in the mixture.
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PO2
Partial Pressure of atmospheric O2
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PCO2
Partial Pressure of atmospheric CO2
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Inspired air
gets heated to body temperature & saturates it with water
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PIO2
the pressure of inspired oxygen in the trachea
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PH2O
the partial pressure of water equal to approximately 47mm Hg. It also takes up space .
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Minute Ventilation (MV)
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V
E
How much air are you moving per minute in terms of liters.
- · (Over time )
- V (ventialtion)
- E (expiratory)
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Tidal Volume (TV)
How much air you move in and out with each breath.
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Normal Tidal volume
500 MLs
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Volume of air entering & leaving lungs each minute
Minute Ventilation
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How is PIO2 calculated?
PiO2 = FiO2 x (barometric pressure – saturated vapor pressure of H20)PiO2 = 0.21 x (760 – 47) – sea level.PiO2 = 150mmHg.gas supply pressures are continuously measured.
Note; Normal body temp and human this 47% will never change
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Tidal Volume Ranges
400,450,500
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Respiratory Rate (RR) normal ranges
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Calculation is given based on IBW for which calculations?
- Minute Ventilation (MV) and
- Sometimes Dead Space for patients who appear to be super short or super tall
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How many ML of Tidal volume per Kg of IBW?
6 ML
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Does 300 Kg necessarily increase the lung volumes
No
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Calculate the minute ventialtion for a man who IBW is 70 Kg.
- 6 * 70=420 ml
- TV * RR = Minute Ventilation
- 420 * 20 = 8400 Minutes =8.4L
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How do you calculate the minute volume?
Minute volume is calculated by taking the tidal volume and multiplying the respiratory rate (the number of breaths per minute a person is taking).
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Alveolar minute ventilation
is less than minute ventilation and is calculated as ([tidal volume − dead space] × respiratory rate) or ([500 mL − 150 mL] × 12 breaths/min) = 4200 mL/min.
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Anatomical dead space is represented by
the volume of air that fills the conducting zone of respiration made up by the nose, trachea, and bronchi. This volume is considered to be 30% of normal tidal volume (500 mL); therefore, the value of anatomic dead space is 150 mL.
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Alveolar ventilation rate
AVR=(TV- dead space)* # of breaths/min=(500 ml -150 ml) (12)=(350)(12)=4200 ml/min
we're going to subtract the Dead Space from that title volume so we'll take the title volume subtract the Dead Space from it and then still multiply it times the frequency of breathing or the number of breaths per minute and so the alveolar ventilation right you can see is an equation that's similar to the minute respiratory volume you just correcting it for the Dead Space
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normal dead space
is 20-40% of our air that we breath
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This is a normal value for dead space/ Tidal volume
20-30 / 40 = 0.25 or 25%
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Effective portion of ventilation
V ·
A
- Alveolar Ventilation
- V (means ventilation)
- · (means Over Time)
- Alveolar
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Dead space
portion of inspired air that never reaches alveoli
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Dead space Ventilation
Three types of Dead space Ventilation- Anatomical, Alveolar and Physiological
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Anatomic Dead space Value
150 ml (30% of 500 ml)
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Anatomical Dead Space-
Nose, trachea, bronchi
conducting Airways, NO gas exchange
gas composition changes inspiration to expiration
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What is the normal tidal volume
500 MLs
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Alveolar Dead Space
When your calculation is not what you expected in addition to anatomical
*Volume in non-perfused (no blood supply) alveolae
*ABNORMAL condition
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Physiological Dead Space
the SUM of anatomical and alveolar Dead Spaces
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VD/VT
Dead space / Tidal volume
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Bohr Equation
Calculating Vd/Vt (Dead space to tidal volume) Ratios
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What is the name of this equation?
–Vd/Vt = PaCO2 – PECO2
PaCO2
Bohr Equation
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measure carbon dioxide CO2 in expired air and provides clinicians with a noninvasive measure of systemic metabolism, circulation, and ventilation.
Capnometer
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Tidal volume (normal)
500 MLs
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Calculate TV
dead space * RR
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Calculate TV with out deadspace
Use IBW
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Calculate the Ideal Body Weight in pounds for the following individual:Male 6’2” tall
50 +(2*14) =78 + 2= 80Kg *2.2=176 lbs (IBW)
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Calculate the Ideal Body Weight in pounds for the following individual. Female 5’2” tall
118.8 Lbs
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What is the formula for IBW
- IBW = 50 kg + (2 x each inch over 5’)
- Add 2 for men
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