______ ______ ______: found in developing and adult brains.
Neural Stem Cells
True or False: The Nervous System has an infinite ability to repair itself.
False
Dendrites are responsible for?
A. major input site from cells/receive info from other cells (project from soma)
Axons are responsible for output of info via NT's and originate from _______ _______?
axon hillock
Axons end in the ________ _______ where they release NT into the _________ ______.
Presynaptic terminal
synaptic cleft
_____________: contains genetic material; directs metabolic activity of cell.
Nucleus
______________: converts nutrients to energy.
Mitochondria
_____________: rough: synthesizes and transports proteins; smooth: synthesizes and transports lipids.
Endoplasmic Reticulum
__________: protein synthesis; on rough= protein for neuron; on smooth= NTs
Ribosomes
___________: packages NT
Golgi apparatus
NT transport: _________: from soma to synapse; Kinesin.
Anterograde
NT transport: ___________: from synapse to soma: Dynein.
Retrograde
__________: has only one process extending from soma, branching into dendrites or axon terminals.
Unipolar
_________: two primary processes from cell body.
Bipolar
__________: multiple dendrites and single axon
Multipolar
__________: appear to have single projection that divides into axonal roots.
Pseudounipolar
______ _______: support cells: provide metabolic support, insulate, protect, reinforce, repair, and cleanup damaged areas.
Glial Cells
__________: • Star-shaped• CNS• Support and also signaling• Stimulated by:– Signals from other cells– Changes in shape or pressure• Diffuse Ca++ through openings (Gap Junctions) to otherAstrocytes when stimulated• Can release NT: Glutamate• No synaptic contacts• Do not generate Action Potentials (APs)• Scavengers: take up extra K+ and NTs and remove debris• Connect Neurons and blood vessels• Pathway for migrating neurons
Astrocytes
___________: myelinate CNS; insulate axon; envelop several axons to different neurons.
Oligodendrocytes
________ ________: Myelinate PNS; ingest and remove bacteria and debris; envelope one or several axons.
Schwann Cells
________ ________ _______: • Cells have an excitable membrane:– Nerves, Muscles, some glands• At Rest = not generating impulses• Inside of cell is negative compared to outside
Resting Membrane Potential
__________: atoms or molecules with a net charge
Ions
_______: cause chem reactions in neurons __________: shape of neuron
___________: sensitive to NT
Enzymes
Cytoskeleton
Receptors
_____ ______: Hydrophilic ends = exposed to watery insideand outside– Hydrophobic middle = in membrane– 4-6 similar proteins bond to form a pore
Ion channels
_____ _____: formed by proteins– Use energy released from ATP breakdown totransport ions across membrane
Ion pumps
_______ _______: ions flow DOWNgradient until EQUALon both sides
Concentration gradient
_______ ________ ________: walls of capillaries thatlimits K+ movement into extracellular fluid ofbrain
Blood-brain Barrier
_________: take up extracellular K+when concentrations rise and disperse the K+over network of astrocytic processes