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Over reactivity to an antigen resulting in tissue damage.
Hives, eczema, swelling of lips or tongue, abdominal cramps, diarrhea, anaphylactic shock (respiratory distress, cardiovascular failure)
Allergy
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Reduced by matching donor with recipient antigens and immunosuppressive drugs inhibiting antibody formation.
Tissue rejection
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Outside of the body:
A heart lasts ____
A liver lasts _____
A kidney lasts ____
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The body’s immune system attacks certain body tissues
Autoimmune diseases
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Why does the immune system attack certain body tissues?
- -Viruses with a human cell protein “teach” the T cells to destroy similar human cells
- -T cells have never learned to distinguish self from nonself
- -A nonself antigen coincidentally resembles a self antigen (rheumatic fever)
Examples: rheumatoid arthritis, lupus, type I diabetes, multiple sclerosis, Graves’ disease
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Rare disease with missing B and T cells.
Both SCID & AIDS are immunodeficiency diseases.
SCID (severe combined immunodeficiency)
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Cells travel from one cell to another
- Malignant
- (not benign) = Opposite of metasis (benign = speed)
- Lymph nodes may be tested
Metasis-Cancer
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Cancer of the lymph nodes. Genetic predisposition, immune disturbance & infections agent (Epstein-Barr virus) are all factors leading to the disease
Hodgkin's Lymphoma
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Any tumor composed of lymphatic tissue
Lymphoma
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a disease causing agent (originates OUTSIDE the body)
Pathogen
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caused by a pathogen
Infection
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Body's response to any pathogen (innate disease resistance)
Nonspecific
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Specific (adaptive) defense that recognizes pathogens
Immunity
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