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BP Tree of life

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  7. CO
    • Cardiac output
    • "blood flow"
    • volume of blood ejected with each cardiac contraction
  8. SV
    Stroke Volume
  9. Determinants of SV
    • Preload
    • Contractility
    • Afterload
  10. Preload
    • Stretching of ventricles before contraction
    • largely function of venous return
  11. Contractility
    Force of ventricular contraction
  12. Afterload
    Force needed to overcome aortic pressure and achieve left ventricular outflow
  13. HR dictated by
    balance between input from SNS & PNS
  14. SNS
    Sympathetic nervous system
  15. PNS
    Parasympathetic nervous system
  16. SVR
    • Systemic Vascular Resistance
    • Resistance of blood flow through body's blood vessels
  17. SVR increases or decreases with contraction
    Increases
  18. SVR increases or decreases with dilation
    decreases
  19. SVR affected by what
    Local and systemic mediatora
  20. Systemic mediators of SVR
    • Vasopressin
    • Angiotensin
    • SNS
  21. SNS in relation to SVR
    • releases catecholamines (hormones made by adrenal glands on top of kidneys)
    • Primarily responsible for basal systemic vascular tone - min to min regulation of BP
  22. Angiotensin + Vasopressin in relation to SVR
    • Causes vasoconstriction
    • More long-term regulation of vascular tone
  23. Local mediators of SVR
    • NO
    • CO2
    • Histamine
    • PGs
  24. NO
    Nitric Oxide
  25. CO2
    Carbon Dioxide
  26. PGs
    • Prostaglandins
    • Lipid compounds derived from arachidonic acid, have varying hormone-like effects
  27. Local mediators response to what?
    Change in metabolic demand, muscle activity, vascular injury, and to circumvent systemic vascular control
  28. Vasodilatory local factors
    • NO
    • CO2
    • Histamine
    • Prostacyclin (PG)
  29. Vasoconstrictive local factors
    • Endothelin
    • Thrombin
    • Thromboxane (PG released from plts)
Author
anubis_star
ID
357869
Card Set
BP Tree of life
Description
Updated

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