Sharad Medicine

1501. During cardiopulmonary resuscitation intravenous calcium gluconate is indicated under all of the following circumstances except:

1502. Diagnosis of rotavirus diarrhea is confirmed by:

1503. The most specific investigation for rotavirus infection is:

1504. The ECG changes seen in hyperkalemia are all of the following except :

1505.Polymyositis involves all of the following muscles except:

1506. The drug of choice in the treatment of PSVT is:

1507. The patent ductus arteriosus connects aorta and:

1508. Neurological complications of meningitis include all of the following except :

1509. Following cranial nerve is most commonly involved in patients with sarcoidosis:

1511. All of the following murmurs may be heard in patients with aortic regurgitation except:

1512. The most recent advance in non-invasive cardiac output monitoring is use of:

1513. ASD is seen in all except:

1514. Selective media for TB bacilli is:

1515. Drug of choice in anaphylaxia:

1516. A 70 year old man was administered penicillin intravenously. Within 5 minutes, he developed generalized urticaria, swelling of lips, hypotension and bronchospasm. The first choice of treatment is to administer:

1517. A 30 year old man presented with nausea, fever and jaundice of5-days duration. The biochemical tests revealed a bilirubinof 6.7 mg/dl( conjugated 5.0 mg/dl) with SGOT/SGPT (AST /ALT) of 123/900 IU/ml. the secrological tests showed presence of HBsAG, IgM anti-HBc and HBeAg. The most likely diagnosis is;

1518. The drug of choice for chemoprophylaxis in contacts of patients of pneumonic plague is:

1519. All of the following statements regarding the ECG in acute pericarditis are true except :

1520. Troponin T is preferable to CPK-MB in the diagnosis of acute MI in all of the following situations except:

1521. A 60 year old man is diagnosed to be suffering from legionnaire’s disease after he returns home from attending convention. He could have acquired it:

1522. The following are true regarding lyme disease, except :

1523. A 30 year old HIV positive patient presents with fever, dyspnea and non-productive cough. Patient is cyanosed. His chest X-ray revelas bilateral, symmetrical interstitial infiltrates. The most likely diagnosis is:

1524. True regarding methemoglobinemia is:

1525. Reye’s syndrome is caused by:

1526.All of the following are X-linked transmissions except :

1527. All of the following autosomal recessive except :

1528. Turner’s syndrome karyotype is:

1529. A 19 year old female with short stature wide spread nipples and primary amenorrhea most likely has a karyotype of:

1530. Which endocrine disorder is associated with epiphyseal dysgenesis?

1531.Normal value in blood analysis is:

1532. In a diabetic it was found that he was suffering from orbital mucormycosis. The treatment to be given to him would include:

1533. Which of the following is an acquired stem cell defect as a cause of anemia:

1534. First abnormality of ALport’s syndrome is:

1535. Men II syndrome is associated with all of the following except :

1536. True about sydenham’s chorea is all of the following except:

1537. Most common cause of sporadic encephalitis is:

1538.All of the following are associated with SLE except:

1539. all of the following parameters indicate prerenal azotemia except:

1540. All of the following changes are seen in hemolytic anemia except :

1541. The primary defect which leads to sickle cell anemia is:

1542. de Quervain’s thyroiditis is characterized by all except :

1543. Metabolic acidosis occurs in all except:

1544. Recent studies show that relapses of P. vivax is due to:

1545.Erysipelas is caused by:

1546.Broca’s are is situated at:

1547. Mesna is used to treat :

1548. Sodium -2-mercapto ethane sulfonte(Mensa) is used as a protective agent in:

1549. True about acute intermittent porphyria (AIP) are all except :

1550. Resistance against anti-TB drug primarily starts from:

1551. Cause of candidiasis all except :

1552. Organism causing dental caries:

1553. Streptococci cause toxic shock syndrome due to:

1554. Which of the following is false regarding Wiskott-aldrich syndrome?

1555. All of the following are associated with increased bone age except:

1556.A 62 year old man with carcinoma of lung presented to emergency department with respiratory distress His EKG showed electrical alternans. The most likely diagnosis is:

1557.Atrial fibrillation may occur in all of the following conditions except:

1558.The occurrence of hyperthyroidism following administration of supplemental iodine to subjects with endemic iodine deficiency goiter is known as:

1559. Which of the following imaging modalities is ‘most sensitive’ for evaluation of extra-adrenal pheochromocytoma:

1560. All are correct about potassium balance except :

1562. dystrophin-gene mutation leads to:

1563. hypocalcemia is characterized by all except :

1564. The level of alpha-fetoprotein is raised in all of the following except :

1565. Which of the following conditions is associated with coombs positive hemolytic anemia:

1566.The severity of mitral stenosis is clinically best decided by:

1567. The risk of developing infective endocarditis is least in a patient with:

1568.Kenny packs were used in the treatment of:

1569.In a patient with polyuria and polydipsia with passage of dilutes urine is suffering from abnormality involving:

1570. the immunological response giving protection to hepatitis A for long periods:

1571.Loss of speech with inability to read, understand in a patient is referred to as:

1572. The blocking antibodies in pernicious anemia are:

1573. Hypertrophic pulmonary osteoarthropathy is seen more commonly with which of the following lung carcinomas:

1574. “pathyergy” test is specific for:

1576. All the following are characteristic of “right ventricular infarction” except:

1577. A young female presents with history of dyspnea on exertion . on examination, she has a wide, fixed split of S2 with ejection systolic murmur (III/IV) in left second intercostals space. Her EKG shows left axis deviation. The most probable diagnosis is:

1578. Which of the following is not seen in cerebral malaria?

1579. Most common primary immunodeficiency is:

1580. Subdural effusion is a complication of which of the following parasite?

1581. Congenital long QT syndrome can lead to:

1582. most common organism causing septicemia in splenectomized patient is:

1583. Phlegmasia cerulean dolens in deep vein thrombosis denotes:

1584. All of the following are implicate in the causation of hepatocellular carcinoma except:

1585.All of the following are useful intravenous therapy for hypertensive emergencies except:

1586. Father –to –so inheritance is never seen in case of:

1587. A young man with tuberculosis presents with massive recurrent hemoptysis. For angiographic treatment which vascular structure should be evaluated first:

1588. The syndrome management of urethral discharge includes treatment of:

1589. A 60 year old hypertensive patient on angiotensin II receptor antagonists (losartan ) is posted for hernia repair surgery. The antihypertensive drug should be:

1590. Which of the following is not an oncologic emergency:

1591. Which of the following markers in the blood is the most reliable indicator of recent hepatitis B infection :

1592. Development of testes is dependent upon which of the following:

1593. Hypocalcemia is characterized by all of the following features except:

1594. All of the following are poor prognostic factors for acute myeloid leukemia, except:

1595. All of the following are the electrocardiographic features of severe hyperkalemia except:

1596. A laborer involved with repair-work of sewers was admitted with fever, jaundice and renal failure. The most appropriate test to diagnose the infection in this patient is:

1597. Following are the features of corticospinal involvement except:

1598. Dressing apraxia is due to lesion of:

1599. A lesion of ventrolateral part of spinal cord will lead to loss( below the level of lesion ) of:

1600. All of the following are true regarding cerebellar lesion except:

1601. Past pointing, intension tremor, slurred speech and drunken gait are seen in the lesions of?

1602. All of the following are seen in cerebellar lesions except:

1603. which of the following is not a usual feature of right middle cerebral artery territory infarct:

1604. Lesion in left inferior frontal gyrus leads to:

1605. Inhibition of 5-lipoxygenase is useful in:

1606. A 56 year old man has painful rashes over his right upper eyelid and forehead for the last 48 hours. He underwent chemotherapy for non-Hodkin’s lymphoma one year ago. His temperature is 98 F, blood pressure s 138/76 mmHg and pulse rate is 80 per minute. Examination shows no other

1607.A 25 year old female presented with mild pallor and moderate hepatosplenomegaly. Her hemoglobin was 9.2 gram per liter and fetal hemoglobin level was 65%. She has not received any blood transfusion till date. She is most likely to be suffering from:

1608.A 41 year old patient presented with chronic diarrhea for 3 months. A D-xylose absorption test was

1609. Which of the following statements is true regarding drug used in parkinsonism?

1610. All of the following are used in the treatment of parkinsonism except :

1611. Which of the following is the most common tumor associated with type-I neurofibromatosis:

1612. A patient undergoing surgery suddenly develops hypotension. The monitor shows that the end-tidal CO2 has decreased abruptly by 15 mmHg. What is the probable diagnosis:

1613.The most common cause of death in a patient with primary amyloidosis is:

1614. The most common infectious agent associated with chronic pyelonephritis is:

1615. Iv bicarbonate is given in:

1616. Chlamydia is best treated by:

1617. A 23 year old woman has experience episode of myalgias effusion, pericarditis and arthralgias without joint deformity over course of several years. The best laboratory screening test ot diagnose her disease would be:

1618. A postoperative cardiac surgical patient developed sudden hypotension, raised central venous pressure, pulses paradoxus at the 4th postoperative hour. The most probable diagnosis is:

1619. The diffusion capacity of lung (DLco) id decreased in all of the following conditions except :

1620. prolactin secretion is inhibited by:

1621. prolactin secretion will be inhibited by:

1622. Epidemics of poliomyelitis are most commonly caused by:

1623.Which of the following Is associated with primary hemochromatosis?

1624. A 6 year old child is brought with history of hemophilia, and swollen and painful right knee joint, factor VIII serum level is 10% . which of the following is the preferred treatment ?

1625. Most common cause of acute cor pulmonale is?

1626.Which of the following is the best indicator of chronic renal failure?

1627. HLA B-27 is associated with all except:

1628. Albendazle is effective against infection with all of the following except:

1629. CD10 is a marker in:

1630. Takayasu’s arteritis most commonly involves:

1631.Which one of the following conditions may lead to exudative pleural effusion ?

1632. A high amylse level in pleural fluid suggests a diagnosis of:

1633. All of the following are causes of decreased glucose in pleural effusion except:

1634. Decreased pleural fluid glucose is seen in all of the following except :

1635. all of the following are true statements regarding acid base balance except:

1636. Which test is performed to detect reversible myocardial ischemia:

1637. the relevance of fibrin degradation products is in:

1638. Familial amloidotic polyneuropathy is due to amyloidosis of nerves caused by deposition of:

1639. The severity of mitral regurgitation is decided by all of the following clinical findings except :

1640.All of the following type of lymphoma are commonly seen in the orbit except:

1641. The nephrotic syndrome with best prognosis is seen in which of the following nephropathies:

1642. Congenital transmission is seen in all of the following except:

1643. Congenital transmission is seen in all of the following except:

1644. All of the following heart sounds occur shortly after S2 except:

1645.A patient with a mid-diastiolic murmur with loud S1 and S2 at the apex is most likely suffering from:

1646. In a patient presenting with episodic jaundice and conjugated hyperbilirubinemia had normal liver biopsy. The most likely diagnosis is:

1647. True regarding multiple respiratory papillomatosis is all of the following except:

1648. a patient with CRF is having normocytic anemia. Which of the following drugs is most likely to correct it:

1649.All of the following are associated with increased pigmentation except:

1650. All of the following are true statements regarding diabetic ketoacidosis except:

1651.True regarding primary hypothyroidism is:

1652. the best drug in treatment of motion sickness among the following is;

1653. lyme disease caused by:

1654. A patient presents with respiratory symptoms I.e. cough, hemoptysis and glomerulonephritis. His c-ANCA level in serum is raised. The most likely diagnosis is:

1655. The pathogenesis of hypochromic anemia in lead poisoning is due to:

1656. Dystrophic calcification is seen in:

1658. In type II respiratory failure, there is:

1659. Which of the following imaging modality is most sensitive to detect early renal tuberculosis:

1660. Microangiopathic hemolytic anemia is seen in all except:

1661. ‘c’ wave in JVP corresponds to:

1662.s False about pyloric stenosis:

1663. which of the following symbol represent adopted individuals:

1664.Choose the false statement regarding hepatitis G virus:

1666. A 15 year old boy presents to you with history of fever, altered sensorium and purpuric rash for two days. On examination , the patient is found stuporous. He ahs a BP of 90/60 mmHg and extensive palpable purpura over the legs . which of the following would be the most appropriate initial choice of antibiotic?

1667. A 55 year old man a chronic smoker is brought to emergency with history of polyuria, polydipsia, nausea and altered sensorium for last two days. He had been diagnosed as having squamous cell carcinoma of lung two months prior to this. On examination , he was lethargic and confused . an ECG was normal except for a narrowed QT interval. Which one of the following is the most likely metabolic abnormality?

1668. Tumor lysis syndrome is associated with all of the following laboratory features, except:

1669. All of the following drugs are useful in the treatment of a patient with acute bronchial asthma except :

1670. A normal anion gap metabolic acidosis occurs in patients with:

1671. A 41 year old male patient presented with recurrent episodes of bloody diarrhea for 5 years. Despite regular treatment with adequate doses of sulfasalazine, he has had several exarcerbations of his disease and required several weeks of steroids for the control of flares. What should be the next line of treatment for him:

1672. a 55 year old male patient was diagnosed to have chronic hepatitis C. he responded to treatment with interferon , however, after one year of follow up he showed a relapse of disease. Which of the following would be the next most appropriated choice?

1673. In malignant hyperthermia the increased heat production is due to:

1674. Which of the following management procedures of acute upper gastrointestinal bleed should possible be avoided:

1675.Early diagnosis of acute hepatitis B infection is made by:

1676. Duchenne muscular dystrophy is disease of:

1677. Which of the following is the drug of first choice for non-gonococcal urethritis?

1678. Ataxia telangiectasia is characterized by all of the following except:

1679.Hemoglobin A 1c level in blood explains:

1680.The first investigation of choice in patient with suspected subarachnoid hemorrhage should be:

1681. Elevated serum ferritin, serum iron and percent transferriin saturation are most consistent diagnosis of:

1682. Estimation of the following hormones is useful while investigating a case of gynecomastia except :

1683. Estimation of the following hormones is useful while investigating a case of gynecomastia, except:

1684. Which of the following is the treatment of choice for Kawasaki disease?

1685. Which one of the following is not a feature of multiple myeloma?

1686. Which one of the following diseases is an autosomal dominant disorder?

1687. Which one of the following lymphomas is associated with HTLV-I virus infection ?

1689. The most appropriate drug for the treatment of bulimia nervosa is:

1690.Carcinoid syndrome produces valvular disease primarily involving :

1691. all of the following conditions are observed in marasmus, except:

1692. Bart’s hydrops fetalis is tethal because:

1693. Which of the following is a cause of reversible dementia :

1694.Vitamin B12 deficiency can give rise to all of the following except :

1695. Which one of the following is used in therapy of toxoplasmosis?

1696. Which of the following drugs is useful in prophylaxis of migraine ?

1697. Antipsychotic drug-induced parkinsonuism is treated by:

1698. Which of the following infestation leads to malabsorption ?

1699. All of the following can cause osteoporosis except:

1700. Hypercalcemia associated with malignancy is most often mediated by:

1701. All of the following are the causes of ‘relative’ polycythemia, except:

1702. 5’ –nucleotidase activity is increased by:

1703. Normal CSF glucose level in a normoglycemic adult is:

1704. All of the following may cause ST segment elevation on ECG , except:

1705. The most sensitive test for the diagnosis of myasthenia gravis is:

1706. Not a neurologic channelopathy:

1707. all of the following are neurological channelopathies , except:

1708.All of the following are calcium channelopathies except :

1709.At what value of one hour glucose challenge test will you recommend a standard glucose tolerance test?

1710. A 50 year old man alcoholic and a smoker presents with a 3-hour history of severe retrosternal chest pain and increasing shortness of breath. He started having this pain while eating, which was constant and radiated to the back and intercapular region. He was a known hypertensive. On examination, he was cold and clammy with a heart rate of 130 /min , and a BP of 80/40 mm Hg. JVP was normal . all peripheral pulses were present and equal. Breath sounds were decreased at the left lung base and chest X-ray showed left pleural effusion. Which one of the following is the most likely diagnosis?

1711. A 30 year old male patient presents with complaints of weakness in right upper and both lower limbs for last 4 months. He developed digital infarcts involving 2nd and 3rd fingers side and 5th finger in left side. On examinations, BP was 160/140 mm Hg, all peripheral pulses were palpable and there was asymmetrical neuropathy. Investigations showed Hb-12 gm, TLC -12000 CU mm, platelets-4,30,000, ESR- 49 mm. urine examination showed proteinuria and RBC 10-15 per HPF with no casts. Which of the following is the most likely diagnosis?

1712. All of the following conditions are known to cause diabetes insipidus, except:

1713. Increased susceptibility to breast cancer is likely to be associated with a mutation in the following gene:

1714. The most common pathogens responsible for nosocomial pneumonias in the ICU are:

1715. Ropinirole’s is most useful for treatment of:

1716.In which of the following arthritis erosions are not seen?

1717. Flapping tremors are seen in the following conditions except:

1718. All of the following are true regarding tetralogy of fallot, except:

1719. Which one of the following is not a feature of irritable bowel syndrome:

1720. In which of the following conditions of malabsorption, an intestinal biopsy is diagnostic?

1721. Hemolytic anemia may be characterized by all of the following except:

1722. Recurrent facial/oropharyngeal/ laryngeal edema in a patient having low C4 , normal C3 and normal factor B. The pathogenesis is most likely due to:

1723. There is mutation of gene coding for the ryanodine receptors in malignant hyperthermia. Which of the following statements best explains the increased heat production in malignant hyperthermia?

1724. All of the following conditions are observed in gout, except:

1725. which of the following statement is false regarding Wilson’s disease?

1726. False regarding creutzfeldt-jakob disease:

1727.Which of the following is not a feature of juvenile myoclonic epilepsy?

1728. A 20 year old female presents with history of dyspnea on exertion. On examination she has wide fixed split of S2 with ejection systolic murmur (III/Iv) in left second intercostals space. Her EKG shows left axis deviation. The most probable diagnosis is:

1729. The only thrombolytic agent approved for the treatment of acute ischemic stroke is:

1730. The most common cause of sporadic viral encephalitis is:

1731. A 27 year old man is noted to have blood pressure of 170/100 mm Hg. He has prominent aortic ejection click and murmurs heard over the ribs on both sides anteriorly and over the back posteriorly. In addition , the pulses in the lower extremities are feeble and he complains of mild claudication with exertion . the most likely diagnosis is:

1732. A 62 year old diabetic female patient presented with history of progressive right sided weakness of one-month duration . the patient was also having speech difficulty. Fundus examination showed papilledema. Two months ago, she also had a fall in her bathroom and struck her head against a wall. The most likely clinical diagnosis is:

1733. All of the following can cause hyeprcalcemia , except:

1734. Humoral immunodeficiency is suspected in a patient and he is under investigation. Which of the following infections would not be consistent with the diagnosis?

1735. In a ptient with listeria meningitis who is allergic to penicillin , the antimicrobial of choice is:

1736. Migratory thrombophlebitis is associated with the following malignancies except:

1737. Which of the following is the most common extra-renal involvement in autosomal dominant polycystic kidney disease?

1738. Which of the following is generally not seen in ITP?

1739. Which of the following arbovirus diseases has not been reported in India?