-
1. The cell junctions allowing exchange of cytoplsmic molecules between two cells are called:
- A. Gap junctions
- B. Tight junctions
- C. Anchoring junctions
- D. Focal junctions
-
2. The cells belonging to the following type of epithelium are provided with extra reserve of cell membrane:
- A. Transitional
- B. Stratified squammous
- C. Stratified cuboidal
- D. Stratified columnar
-
3. All of the following are examples of traction epiphysis except
- A. Mastoid process
- B. Tubercles of humerus
- C. Trochanter of femur
- D. Condyles of tibia
-
4 All of the following statements are true for metaphysis of bone except:
- A. It is the strongest part of bone
- B. It is the most vascular part of bone
- C. Growth activity is maximized here
- D. It is the region favouringhematogenous spread
-
5. All of the following features can be observed after the injury to axillary nerve, except:
- A. Loss of rounded contour of shoulder of infection
- B. Loss of sensation along lateral side of upper arm
- C. Loss of overhead abduction
- D. Atrophy of deltoid muscle
-
6. Injury to radial nerve in lower part of spiral groove:
- A. Spares nerve supply to extensor carpi radialislongus
- B. Results in paralysis of anconeus muscle
- C. Leaves extensions at elbow joint intact
- D. Weakens pronation movement
-
7. The right coronary artery supplies all of the following
- parts of the conducting system in the heart except:
- A. SA Node
- B. AV Node
- C AV Bundle
- D. Right Bundle branch
-
8. The middle cardiac vein is located at the:
- A. Anterior interventricular sulcus
- B. Posterior interventricular sulcus
- C. Posterior AV groove
- D. Anterior AV groove
-
9. In a patient with a tumor in superior mediatinum compressing the superior vena cava, all of the following veins would serve as altenate pathways for the blood to return to the right atrium, except
- A. Lateral thoracic vein
- B. Internal thoracic vein
- C Hemiazygos vein
- D. Vertebral venous plexus
-
10. The lumbar region of the vertebral column permits all of the following movements except:
- A. Flexion
- B. Extension
- C. Lateral flexion
- D. Rotation
-
11. The blood vessel related to the paraduodenal fossa is
- A. Gonadal vein
- B. Superior mesentric artery
- C. Portal vein
- D. Inferior mesentric vein
-
12 All of the following muscles are grouped together as muscles of mastication" except
- A. Buccinator
- B. Masseter
- C Temporalis
- D. Pterygoids
-
13. The commonest variation in the arteries arising from the arch of aorta is:
- A. Absence of brachiocephalic trunk
- B. Left vertebral artery arising from the arch
- C. Left common carotid artery arising from brachio cephalic trunk
- D. Presence of retroesophagealsubclavian artery
-
14. All of the following statements are correct about potassium balance, except
- A. Most of potassium is intracellular
- B. Three quarter of the total body potassium is found in skeletal muscle
- C. Intracellular potassium is released into extra- cellular space in response to severe injury
- D.Acidosis leads to movements of potassium from extracellular to intracellular fluid compartment
-
15. Synaptic conduction is mostly orthodromic because:
- A. Dendrities cannot be depolarized
- B. Once repolarized, an area cannot be depolarized
- C. The strength of antidromic impulse is less
- D. Chemical mediator is localised only in the presynaptic terminal
-
16. Which of the following statements is true for excitatory postsynaptic potentials (EPSP)?
- A. Are self propagating
- B. Show all or none response
- C. Are proportional to the amount of transmitter released by the presynaptic neuron
- D. Are inhibitory at presynaptic terminal
-
The EEG recorded shown below is normally recordable
- during which stage of sleep?
- 17.
- Sleeynde
- A. Stage
- B. Stage
- C Stage lll
- D. Stage IV
-
18. A lesion of ventrolateral part of spinal cord will lead to loss (below the level of lesion) of
- A. Pain sensation on the ipsilateral side
- B. Proprioception on the contralateral side
- C. Pain sensation on the contralateral side
- D. Propriception on the ipsilateral side
-
19. Following are the features of corticospinal involvement except:
- A. Cog-wheel rigidity
- B. Spasticity
- C Planter extensor response
- D. Exaggerated deep tendon reflexes
-
20. Which of the following statements is true about the autonomic nervous system?
- A. The sympathetic outflow from the CNS is through both the cranial nerves and the sympathetic chain
- B. The parasympathetic outflow from the CNS is through cranial nerves only
- C. The superior hypogastric plexus is located at the anterior aspect of the aortic bifurcation and fifth lumbar vertebra.
- D. The superior hypogastric plexus contains sympathetic fibres only
-
21. Positive feedback action of estrogen for inducing luteininzing hormone surge is associated with which of the following steroid hormone ratios in peripheral circulation:
- A. High estrogen : low progesterone
- B. Low esterogen : high progesterone
- C. Low esterogen low progesterone
- D. High esterogen: high progesterone
-
22. Figure below represents the pH of the digestive jül
- aspirated from the aliment
- fong the alimentary tract during digestion of a
- mcal:
- ole
- Y2
- A B C D E
- Position along
- Food alimentary canal
- entering
- A. A typical value for Y2 is 9.0
- B. A typical value for Y3 is 10.0
- C The segment C represents the pylorus
- D. The digestive enzymes active in segment A are to inactivated in segment B
-
23. As a part of space-research program, a physiologist was asked to investigate the effect of flight-induced stress on blood pressure. Accordingly. the blood pressure of the. cosmonauts were to be measured twice: once before the take-off and once after the spacecraft entered the signated orbit around the earth. For a proper comparison, the preflight blood pressure should be recorded in
- A. The lying down position
- B. The sitting position
- C The standing position
- D. Any position, as long as the post-flight recording is made in the same position
-
24. Two students, Vineet and Kamlesh were asked to demonstrate in dogs the role of sinus nerve in hypovolemic shock. Vineet severed the sinus nerve when the mean blood pressure (MBP) was 85 mm Hg and Kamlesh cut the sinus nerve when the mean blood pressure was 60 mm Hg. On cutting the sinus nerve
- A. Vineet recorded the increase in MBP but Kamlesh recorded a decrease in MBP
- B. Vineet recorded a decrease in MBP but Kamlesh recorded an increase in MBP
- C. Both recorded an increase in MBP
- D. Both recorded a decrease in MBP
-
25. An increase in which of the following parameters will shift the O, dissociation curve to the left
- A. Temperature
- B. Partial pressure of Co
- C 2.3DPG concentration
- D. Oxygen affinity of hemoglobin
-
26. The renal plasma flow (RPF) of a patient was to be estimated through the measurement of Para Amino Hippuric acid (PAH) clearance The technician observed the procedures correctly but due to an error in the weighing inadvertently used thrice the recommended dose of PAH The RPF estimated is likely to be
- A. False high
- B. False-low
- C. False-high or false-low depending on the GFR
- D. Correct and is unafected by the PAFH overdose
-
27. In the presence of vasopressin the greatest fraction of filtered water is re-absorbed which part of the nephron:
- A. Proximal tubule
- B. Distal tubule
- C Loop of Henle
- D. Collecting duct
-
28. The buffering capacity of a buffer is maximum at pff
- equal to
- A. 0.5 pKa
- B. pKa
- C. pKa+1
- D. 2pKa
-
29. The following separation technique depends on the molecular size of the protein
- A. Chromatography on a carboxymethyl (CM)cellulose column
- B. Iso-electric focussing
- C. Gel filtration chromatography
- D.Chromatography on a diethylaminoethyl (DEAE) cellulose column
-
30. The conversion of an optically pure isomer (enantiomer) into a mixture of equal amounts of both dextro and levo forms is called as
- A. Polymerization
- B. Stereoisomerization
- C. Racemization
- D. Fractionation
-
31. Decreased glycolytic activity impairs oxygen transport by hemoglobin due to
- A. Reduced energy production
- B. Decreased production of 2,3bisphosphoglycerate
- C Reduced synthesis of hemoglobin
- D. Low levels of oxygen
-
32. An enzyme involved in the catabolism of fructose to pyruvate in the liver is
- A. Glyceraldehyde-3-phosphate Dehydrogenase
- B. Phosphoglucomutase
- C. Lactate-dehydrogenase
- D. Glucokinase
-
33. p oxidation of odd-chain fatty acids produces:
- A. Succinyl CoA
- B. Propionyl CoA
- C. Acetyl CoA
- D. Malonyl CoA
-
34. The protein rich in basic amino acids, which functions the packaging of DNA in chromosomes, is:
- A. Histone
- B. Collagen
- C Hyaluronic acid binding protein
- D. Fibrinogen
-
35. Which of the following is not a post transcriptional modification of RNA?
- A. Splicing
- B. 5'capping
- C 3'polyadenylation
- D. Glycosylation
-
36. Restriction fragment length polymorphism is used for
- A. Analysis of chromosome structures
- B. DNA estimation
- C. Synthesis of nucleic acid
- D. Detecting proteins in a cell
-
37. The primary role of chaperones is to help in
- A. Protein synthesis
- B. Protein degradation
- C. Protein denaturation
- D. Protein folding
-
38. The collagen triple helix structure is not found in:
- A. Cytoplasm
- B. Golgi apparatus
- C. Lumen of endoplasmic reticulum
- D. Intracellular vescicles
-
39. The main enzyme responsible for activation of xenobiotics is
- A. Cytochrome P-450
- B. Glutathione S-transferase
- C NADPH cytochrome P-450-reductase
- D. Glucuronyltransferase
-
40. The substance present in the gall bladder stones or the kidney stones can be best identified by the following techniques
- A. Fluorescence spectroscopy
- B. Electron microscopy
- C. Nuclear magnetic resonance
- D. X-ray diffraction
-
41. Prophobilinogen in urine produces pink colour with
- A. Fouchet's reagent
- B. Benedict's reagent
- C. Sodium nitropruside
- D. Ehrlich's aldehyde reagent
-
42. All of the following statements regarding bioavailability of a drug are true except
- A. It is the proportion (fraction) of unchanged drug that reaches the systemic circulation
- B. Bioavailability of an orally administered drug can be calculated by comparing the Area Under Curve (0-a) after oral and intravenous (iv) administration
- C. Low oral bioavailability always and necessarily mean poor absorption
- D. Bioavailability can be determined from plasma concentration or urinary excretion data
-
43. Presence of food might be expected to interfere with drug absorption by slowing gastric emptying, or by altering the degree of ionisation of the drug in the stomach. Which of the following statements is not correct example
- A. Absorption of digoxin is delayed by the presence of food
- B. Concurrent food intake may severely reduce the rate of absorption of phenytoin
- C. Presence of food enhances the absorption of hydrochlorthiazide.
- D.Antimalarial drug halofantrine is more extensively absorbed if taken with food
-
44. All of the following are useful intravenous therapy for hypertensive emergencies except
- A. Fenodolpam
- B. Urapidil
- C. Enalapril
- D. Nifedipine
-
45. Cardiac or central nervous system toxicity may result when standard lidocaine doses are administered to patients with circulatory failure. This may be due to the following reason:
- A. Lidocaine concentration are initially higher in relatively well perfused tissues such as brain and heart
- B. Histamine receptors in brain and heart gets suddenly activated in circulatory failure
- C. There is a sudden out-burst of release of adreneline, noradreneline and dopamine in brain and heart
- D. Lidocaine is converted into a toxic metabolite due to its longer stay in liver.
-
46. Haemorrhage secondary to human administration can be corrected by administration of
- A. Vitamin K
- B. Whole blood
- C. Protamine
- D. Ascorbic acid
-
47. Granulocytopenia, gingival hyperplasia and faciahirsutism are all possible aide effects of one of the following anticonvulsant drugs
- A. Phenytoin
- B. Valproatc
- C Carbamazepine
- D. Phenobarbitone
-
48. Which of the following is present intracellularly in muscle cells
- A. Insulin
- B. Corticosteroid
- C. Epinephrine
- D. Glucagon
-
49. All of the following drugs act on cell membrane, except
- A. Nystatin
- B. Griscofulvin
- C Amphotericin B
- D. Polymixin B
-
50. Bacitracin acts orn:
- A. Cell Wall
- B. Cell Membrane
- C. Nucleic Acid
- D. Ribosome
-
51. The most effective drug against M. leprae is:
- A. Dapsone
- B. Rifampicin
- C Clofazamine
- D. Prothionamide
-
52. The most appropriate drug used for chelation therapy in beta thalassemia major is:
- A. Oral desferioxamine
- B. Oral deferiprone
- C. Intramuscular EDTA
- D. Oral Succimer
-
53. Bostentan is a
- A. Serotonin uptake inhibitor
- B. Endothelin receptor antagonist
- C. Leukotriene modifier
- D. Calcium sensitize
-
54. The extent to which ionisation of a drug takes place is dependent upon pKa of the drug and the pH of the solution in which the drug is dissolved. Which of the following statements is not correct:
- A. pKa of a drug is the pH at which the drug is 50% ionized
- B. Small changes of pH near the pKa of a weak acidic drug will not affect its degree of ionization.
- C. Knowledge of pKa of a drug is useful in predicting its behaviour in various body fluids
- D.Phenobarbitone with a pKa of 7.2 is largely ionized at acid pH and will be about 40% non ionised in plasma.
-
55 The correct sequence of cell cycle is:
- A. GO-G1-S-G2-M
- B. GO-GI-G2-S-M
- C. GO-M-G2-S-G1
- D. GO-GI-S-M-G2
-
56. Which of the following procedures as routine technique for karyotyping using light microscopy
- A. C-banding
- B. G-banding
- C. Q-banding
- D. Brd V-staining
-
57. A married middle aged female gives history or repeated abortions for the past 5 years. The given below s conceptions pre-natal karyogram.
- This karyogram suggests the following:
- A. Klinefelter's syndrome
- B. Tuner's syndrome
- C. Down's syndrome
- D. Patau's syndrome
-
58. A nineteen year old female with short stature, wide spread nipples and primary amenorrhoea most likely has a karyotype of:
- A. 47, XX+18
- B. 46, XXY
- C. 47 XXY.
- D. 45X
-
59. An albino girl gets married to a normal boy, What are the chances of their having an affected child and what are the chances of their children being carriers?
- A. None affected, all carriers
- B. All normal
- C. 50% carriers
- D. 50% affected, 50% carriers
-
60. A couple, with a family history of beta thalassemia major in a distant relative, has come for counseling. The husband has HbA2 of4.8% and the wife has HbA2 of 2.3%. The risk of having a child with beta thalassemia major is:
-
61. Hereditary Retinoblastoma develop the following chromosomal deletion:
- A. 13 q 14
- B. 13 p 14
- C. 14 p 13
- D. 14 q 13
-
62. Gluten sensitive enteropathy is most strongly associated with;
- A. HLA-DQ2
- B. HLA-DR4
- C. HLA-DQ3
- D. Blood group "B'
-
63. Which of the following is a pan-T lymphocyte marker?
- A. CD2
- B. CD3
- C CD19
- D. CD25
-
64. Memory T cells can be identified by using the following marker
- A. CD45 RA
- B. CD45RB
- C CD45 RC
- D. CD45 RO
-
65. All of the following statements about NK cells are true except
- A. They are derived from large granular cells
- B. They comprise about 5% ofhuman peripheral lymphoid cells
- C. They are MHC restricted cytotoxic cells
- D. They express IgG Fc receptors
-
66. MHC class III genes encode
- A. Complement component C3
- B. Tumor necrosis factor
- C. Interleukin 2
- D. Beta 2 microglobulin
-
67. The HLA class III region genes are important elements in
- A. Tmasplant rejection phenomenon
- B. Goveming susceptibility to autoimmune diseases
- C. Immune surveillance
- D. Antigen presentation and elimination
-
68. All the statement about lactoferrin are true, except:
- A. It is present in secondary granules of neutrophil
- B. It is present in exocrine secretions of body
- C. It has great affinity for iron
- D. It transports iron for erythropoiesis
-
69.The primary defect which leads to sickle cell anemia is
- A. An abnormality in porphyrin part of hemoglobin
- B. Replacement of glutanate by valine in Beta-chain of HbA
- C. A nonsense mutation in the ß-chain of HbA
- D. Substitution of valine by glutamate in the a-chain of HbA
-
70. Raised serum level of lipoprotein-(a) is a predictor of
- A. Cirrhosis of liver
- B. Rheumatic arthritis
- C. Atherosclerosis
- D. Cervical cancer
-
71. Recurrent ischemic events following thrombolysis has been patho-physiologically linked to which of the following factors:
- A. Antibodies to thrombolytic agents
- B. Fibrinopeptide A.
- C. Lipoprotein (a) [Lp(a))
- D. Triglycerides
-
72. Which of the following increases the susceptibility to coronary artery discasce
- A. Type Vhyperlipoproteinacmia
- B. Von willebrandt'sdiscase
- C. Nephrotic syndrome
- D. Systemic lupus erythematosus
-
73. Medullary carcinoma of the thyroid is associated with which of the following syndrome
- A. MENI
- B. MEN II
- C. Fraumeni syndrome
- D. Hashimoto's thyroiditis
-
74. All of the following are associated with low C3 level except:
- A. Post streptococcal glomerulonephritis
- B. Membrano-proliferative Glomerulonephritis
- C. Good pasture's disease
- D. Systemic lupus erythromatosus
-
75. Which of the following is not true about Berger's disease?
- A. The pathological changes are proliferative and usually confined to mesangial cells; usually focal and segmental
- B. Hematuria may be gross or microscopic
- C. On immunofluorescence deposits contain both IgA and IgG
- D. Absence of associated proteinuria is pathognomonic
-
76. A 40 year old male had undergone splenectomy 20 years ago. Peripheral blood smear examination would show the presence of
- A. Dohle bodies
- B. Hypersegmented neutrophils
- C. Spherocytes
- D. Howell-Jolly bodies
-
77. A chest physician performs bronchoscopy in the procedure room of the out patient department. To make the instrument safe for use in the next patient waiting outside, the most appropriate method to disinfect the endoscope is by
- A. 70% alcohol for 5 min
- B. 2% gluteraldehyde for 20 min
- C. 2% formaldehyde for 10 m
- D. 1% sodium hypochlorite for 15 min
-
78. Heat labile instruments for use in surgical procedures can be best sterilized by
- A. Absolute alcohol
- B. Ultra violet rays
- C Chlorine releasing compound
- D. Ethylene oxide gas
-
79. The following are true for Bordetella pertussis except:
- A. It is a strict human pathogen
- B It can be cultured from the patient during catarrhal stage
- C. It leads to invasion of the respiratory mucosa
- D. Infection can be prevented by aacellular vaccine
-
80. A labourer involved with repair-work of sewers was admitted with fever, jaundice and renal failure. The most appropriate test to diagnose the infection in this patiernt
- A. Weil Felix test
- B. Paul Bunnel test
- C Microscopic agglutination test
- D. Micro immunoflurescence test
-
81. A 60-year old man is diagnosed to be suffering from Legionnaires' disease after he returns home from attending a convention. He could have acquired it
- A. From a person suffering from the infection while travelling in the aeroplane
- B. From a chronic carrier in the convention center
- C From inhalation of the aerosol in the air conditioned room at convention center
- D. By sharing an infected towel with a fellow delegate at the convention
-
82. The following are true regarding Lyme's Disease, except:
- A. It is transmitted by ixodes tick
- B. Erythema chronicum migraines may be a clinical feature
- C. Borreliarecurrentis is the aetiological agent
- D. Rodents act as natural hosts
-
83. Thirty-eight children consumed eatables procured from a single source at a picnic party. Twenty children developed abdominal cramps followed by vomiting and watery diarrhea 6-10 hours after the party. The most likely etiology for the outbreak is:
- A Rotavirus Infection
- B. Entero-toxigenic E.coli infection
- C. Staphylococcol toxin
- D. Clostidiumperfringes infection
-
84. Which of the following statements is true about rabies
- virus?
- A. It is double stranded RNA virus
- B. Contains a DNA-dependent RNA polymerase
- C. RNA has a negative polarity
- D. Affects motor neurons
-
85. An anxious mother brought her 4 year old daughter to the pediatrician. The girl was passing loose bulky stools for the past 20 days. This was often associated with pain in abdomen. The pediatrician ordered the stool examination, which showed the following organisms Identify the organism
- A. Entamoebahistolytica
- B. Giardia lamblia
- C. Cryptosporidium
- D. E.Coli
-
86. All of the following infections are often associated with acute intravascular hemolysis except:
- A. Clostridium tetani
- B. Bartonellabacilliformis
- C. Plasmodium falciparum
- D. Babesiamicroti
-
87. The earliest immunoglobulin to be synthesized by the fetus is:
-
88. Mummification refers to:
- A. Hardening of muscle after death
- B. Colliquativeputrifaction
- C. Saponification of subcutaneous fat
- D. Dessication of a dead body
-
89. A patient has been allegedly bitten by cobra snake. The venom in such a bite would be:
- A. Musculotoxic
- B. Vasculotoxic
- C. Cardiotoxic
- D. Neurotoxi
-
90. All the following are related to legal responsibility of an insane pcrson except
- A. McNaughten's rule
- B. Durham's rule
- C. Curren's rule
- D. Rule of nine
-
91. In a suspected case of death due to poisoning where cadaveric rigidity is lasting longer than usual, it may be a case of poisoning due to
- A. Lead
- B. Arsenic
- C. Mercury
- D. Copper
-
92. Blackening and tattooing of skin and clothing can be best demonstrated by:
- A. Luminol spray
- B. Infrared photography
- C Ultraviolct light
- D. Magnifying lens
-
93. Postmortem lividity is unlikely to develop in a case of
- A. Drowning in well
- B. Drowning in a fast flowing river
- C. Postmortem submersion
- D. Drowning in chlorinated swimming pool.
-
94. The following situations are associated with rise of temperature after death except
- A. Burns
- B. Heat stroke
- C Pontine hemorrhage
- D. Septicemia
-
95. In prenatal diagnostic technique Act 1994 which one of the following is not a ground for carrying out prenatal test
- A. Pregnant women above 35 years of age
- B. History of two or more spontaneous abortion or fetal loss
- C. When fetal heart rate is 160 per min at fifth and 120 per min at ninth month.
- D. History of exposure to potentially teratogenic drugs
-
96. Perjury means giving willful false evidence by a witness while under oath, the witness is liable to be prosecuted for perjury and the imprisonment amy extend to seven years. This falls under which section of IPC
- A. 190 ofIndian Penal Code
- B 191 ofindian Penal Code
- C 192 of Indian Penal Code
- D. 193 of Indian Penal Code
-
97. The most reliable criteria in Gustafson's method of identification is
- A. Cementum apposition
- B. Transparency of root
- C. Attrition
- D. Root resorption
-
98. Denominator while calculating the secondary attack rate includes:
- A. All the people living in next fifty houses
- B. All the close contacts
- C All susceptible amongst close contact
- D. All susceptible in the whole village
-
99. In one single visit, a 9-month-old, unimmunized child can be given the following vaccination.
- A. Only BCG
- B. BCG DPT-1, OPV-1
- C. DPT-1,0PV-1, Measles
- D. BCG DPT-1, OPV-1, Measles
-
100. Study this formula carefully True positives/ (True positives + False negatives) X 100 This denotes
- A. Sensitivity
- B. Specificity
- C Positive Predictive value
- D. Negative Predictive value
-
101. For the calculation of positive predictive value of a screening test, the denominator is comprised of:
- A. True positives + False negatives
- B. False positives + True negatives
- C. True positives + False positives
- D. True positives + True negatives
-
102. For calculation of sample size for a prevalence study all of the following are necessary except:
- A. Prevalence of the disease in populatiorn
- B. Power of the study
- C. Significance level
- D. Desired precision
-
103. The parameters of sensitivity and specificity are used for assessing:
- A. Criterion validity
- B. Construct validity
- C. Discriminant validity
- D. Content validity
-
104. The following statements about meningococcal meningitis are true except
- A. The source of infection is mainly clinical cases
- B. The disease is more common in dry and cold months of the year
- C. Chemoprophylaxis of close contacts of cases is recommended
- D.The vaccines is not affective in children below 2 years of age
-
105. A child aged 24 months was brought to the Primary Health Centre with complaints of cough and fever for the past 2 days. On examination, the child weighed 11 kg, respiratory rate was 38 per minute, chestindrawing was present. The most appropriate line of management for this patient is?
- A. Classify as pneumonia and refer urgently to secondary level hospital
- B. Classify as pneumonia, start antibiotics and advise to report after 2 days
- C. Classify as severe pneumonia, start antibiotics and refer urgently
- D. Classify as severe pneumonia and refer urgently
-
106. For controlling an outbreak of cholera, all of the follow ing measures are recommended except
- A. Mass chemoprophylaxis
- B Proper disposal ofexcreta
- C Chlorination of water
- D. Early detection and management of cases
-
107. The organism most commonly causing genital filariasis in most parts of Bihar and Eastern U.P. is
- A. Wuchereriabancrofti
- B. Brugiamalayi
- C Onchocerca volvulus
- D. Dirrofilaria
-
108. Class II exposure in animal bites includes the following:
- A. Scratches without oozing of blood
- B. Licks on a fresh wound
- C Scratch with oozing of blood on palm
- D. Bites from wild animals
-
109. Which of the following statements is true about endemiç
- A. Is caused by R. rickettsi
- B. Is transmitted by the bite of fleas
- C Has no mammalian reservoir
- D. Can be cultured in chemical defined culture medium
-
110. Leprosy is considered a public health problem if the prevalence of leprosy is more tharn
- A. 1 per 10,000
- B. 2 per 10,000
- C. 5 per 10,000
- D. 10 per 10,000
-
111. In the management of leprosy, Lepromin test is most useful for:
- A. Herd immunity
- B. Prognosis
- C. Treatment
- D. Epidemiological investigations
-
112. Scope of family planning services include all of the following except
- A. Screening for cervical cancer
- B. Providing services for unmarried mothers
- C. Screening for HIV infection
- D. Providing adoption services
-
113. Most important epidemiological tool used for assessing disability in children
- A. Activities of Daily Living (ADL) scale
- B. Wing's Handicaps, Behaviour and Skills (HBS) Schedule
- C. Binet and Simon IQ test:s
- D. Physical Quality of Life Index (POLI)
-
114. The Vitamin A supplmenent administered in "Prevention of nutritional blindness in children programme" contain
- A. 25,000 i.u.
- B. 1 lakh i.u./ml
- C 3 lakh i.u/m
- D. 5lakhi.u/ml
-
115. The Protein Efficiency Ratio (PER) is defined as:
- A. The gain in weight of young animals per unit weight of protein-consumed
- B. The product of digestibility cocíficient and biological value
- C The percentage of protein absorbed into the blood
- D. The percentage of nitrogen absorbed from the protein absorbed from the diet
-
116. Elemental iron and folic acid contents of iron & folic acid adult tablets supplied under the "National Programme for Anaemia Prophylaxis are
- A. 60 mg ofelemental iron and 250 micrograms of folic acid
- B. 100 mg ofelemental iron and 500 micrograms of folic acid
- C. 120 mg ofelemental iron and 750 micrograms of folic acid
- D. 200 mg ofelemental iron and 1000 micrograms of folic acid
-
117. Elemental iron and folic acid contents of pediatric iron folic acid tablets supplied under Rural Child Health (RCH) programme are
- А. 20mg iron & 100 microgramı folic acid
- B. 40 mg iron & 100 microgram folic acid
- C. 40mg iron&50 microgram folic acid
- D. 60 mg iron & 100 microgram folic acid
-
118. A measure of location which divides the distribution in the ratio of 3:1 is:
- A. Median
- B. First quartile
- C. Third quartile
- D. Mode
-
119. The 'P' value of a randomized controlled trial comparing operation A (new procedure) & operation B (Gold standard) is 0.04. From this, we conclude that
- A. Type ll error is small & we can accept the findings of the study
- B. The probability of false negative conclusion that operation A is better than operation B when in truth it is not, is 4%
- C. The power of study to detect a difference between operation A & B is 96%.
- D. The probability of a false positive conclusion that operation A is better than operation B when in truth it is not, is 4%
-
120. Chi-square test is used to measure the degree of
- A. Causal relationships between exposure and effect
- B. Association between two variables
- C. Correlation between two variables
- D. Agreement between two observations
-
121. Elements of primary health care include all of the following except
- A. Adequate supply of safe water and basic sanitation
- B. Providing essential drugs
- C Sound referral system
- D. Health Education
-
122 The response which is graded by an observer on an agree or disagree continuum is based on:
- A. Visual analog scale
- B Guttman scale
- C Likert scale
- D. Adjective scale
-
123. Normal anion gap metabolic acidosis is caused by:
- A. Cholera
- B. Starvation
- C. Ethylenc glycol poisoning
- D. Lactic acidosis
-
124. Causes of metabolic alkalosis include all the following except
- A. Mineralocoticoid deficiency
- B. Bartter's syndrome
- C. Thiazide diuretic therapy
- D. Recurrent vomiting
-
125. A 50kg man with severe metabolic acidosis has the following parameters: pH 7.05, pCO2 12 mmHg, pO2 108mm Hg, HCO3 5mEq/L base excess-30 mEq/L. The approximate quantity of sodium bicarbonate that he should receive in half hour is:
- A. 250 mEq
- B. 350 mEq
- С 500 mEq
- D. 750 mEq
-
126. Most sensitive and specific test for diagnosis of iron deficiency is:
- A. Serum iron levels
- B. Serum ferritin levels
- C Serum tmasferrin receptor population
- D. Transferrin saturation
-
127. Leukoerythroblastic picture may be seen in all of the following, excep
- A. Myelofibrosis
- B. Metastatic carcinoma
- C. Gaucher Disease
- D. Thalassemia
-
128. All of the following are poor prognostic factors for acute myeloid leukemias, except
- A. Age more than 60 years
- B. Leucocytes count more than 1,00,000/l
- C. Secondary leukemias
- D. Presence of t(8:21)
-
129. A 63-year old man presented with massive splenomegaly, lymphadenopathy and a total leucocyte count of 17000 per mm. The flowcytometery showed CD19 positive, CD5 positive, CD23 negative, monoclonal B.cells with bright kappa positively comprising 80% of the peripheral blood lymphoid cells The most likely diagnosis is:
- A. Mantle cell lymphoma
- B. Splenic lymphoma with villous lymphocytes
- C. Follicular lymphoma
- D. Hairy cell leukemia
-
130. Which of the following statements represent most
- correct interpretation from the ECG waveform given
- X originated from an atrial ectopic focus
- X reset the cardiac rhythm
- Both heart sounds would have been present at
- X beat
- The path of spread of excitation was nornal
-
131. A 56 year old man presents in the casualty with severe chest pain and difficulty in breathing. His ECG was taken immediately
- The above ECG suggest the following diagnosis:
- A. Ventricular fibrillation
- B. Acute pulmonary embolisnm
- C Second degree heart block
- D. Atrial fibrillation
-
132. All of the following statements regarding the ECG in acute pericarditis are true except
- A. T wave inversions develop before ST clevation
- return to baseline
- B. Global ST segment elevation is seen in early pericarditis
- C. Sinus tachycardia is a common finding
- D. PR segment depression is present in majority of patients
-
133. All of the following are the electrocardiographic features of severe hyperkalemia except:
- A. Peaked T waves
- B. Presence of U waves
- C Sine waves pattem
- D. Loss of P waves
-
134. Hypocalcemia is characterized by all of the following features except
- A. Numbness and tingling of circumoral region
- B. Hyperactivity tendon reflexes
- C Shortening ofQ-T interval in ECG
- D. Carpopedal spasm
-
135. All of the following heart sounds occur shortly after S2 except
- A. Opening snap
- B. Pericardial knock
- C Ejection click
- D. Tumor plop
-
136. An early systolic murmur may be caused by all of the following except
- A. Small ventricular septal defect
- B. Papillary muscle dysfunction
- C. Tricuspid regurgitation
- D. Aortic stenosis
-
137. Exercise testing is absolutely conrtraindicated in which
- one of the following:
- A. One week following myocardial infarction
- B. Unstable angina
- C. Aortic stenosis
- D. Peripheral vascular disease
-
138. The most common cause of tricuspid regurgitation is secondary to
- A. Rheumatoid heart disease
- B. Dilatation of right ventricle
- C. Coronary artery disease
- D. Endocarditis due to intravenous drug abuse
-
139. Which of the heart valve is most likely to be involved by infective endocarditis following a septic abortion
- А. Aortic Valve
- B. Tricuspid Valve
- C. Pulmonary Valve
- D. Mitral Valve
-
14o. Osler's nodes are typically seen in which one of the following
- A. Chronic candida endocarditis
- B. Acute staphylococcal endocarditis
- C. Pseudomonas endocarditis
- D. Libman sack's endocarditis
-
141. Troponin-Tis preferable to CPK-MB in the diagnosis of acute myocardial infarction (MI) in all of the following situations except
- A. Bedside diagnosis of MI
- B. Postopcratively (after CABG)
- C. Reinfarction ate days
- D. Small infarcts
-
142. During cardiopulmonary resuscitation, intravenous calcium gluconate is indicated under all of the followin circumstances except
- A. After 1 mm of arrest routinely
- B. Hypocalcemia
- C Calcium channel blockers toxicity
- D. Electromechanical dissociation
-
143. A post-operative cardiac surgical patient developed sudden hypotension, raised central venous pressure pulsusparadoxus at the 4 post operative hour. The most probable diagnosis is:
- A. Excessive mediastinal bleeding
- B. Ventricular dysfunction
- C. Congestive cardiac failure
- D. Cardiac tamponade
-
144. The blood gas parameters: pH 7.58, pCO2 23 mm Hg pO2 300 mm Hg and oxygen saturation 60% are most consistent with:
- A. Carbon monoxide poisoning
- B. Ventilatory malfunction
- C. Voluntary hyperventilation
- D. Methyl alcohol poisoning
-
145. The diffusion capacity of lung (DLco) is decreased in
- all of the following conditions except
- A. Interstitial lung disease
- B. Goodpasture's syndrome
- C Emphysema
- D. Primary pulmonary hypertension
-
146. A 55 ycar old man who has been on bed rest for the past 10 days, complains of breathlessness and chest pain. The chest X-ray is normal. The next investigation should be
- A. Lung ventilation-perfusion scan
- B. Pulmonary arteriography
- C. Pulmonary venous angiography
- D. Echocardiography
-
147. Diagnostic features of allergiebronchopulmonaryaspergillosis (ABPA) include all of the following except
- A. Changing pulmonary infitrates
- B. Peripheral cosinophilia
- C. Serum precipitins against Aspergillosis fumigants
- D. Occurrence in patients with old cavitatory lesions
-
148. Which one of the following conditions may lead to exudative pleural effusion
- A. Cirhosis
- B. Nephrotic syndrome
- C Congestive heart failure
- D. Bronchogenic carcinoma
-
149. Pulmonary hypertension may occur in all of the following conditions except
- A. Toxic oil syndrome
- B. Progressive systemic sclerosis
- C Sickle cell anemia
- D. Argemonemexicana poisoning
-
150. A 60 year old male presented to the emergency with breathlessness, facial swelling and dilated veins on the chest wall. The most common cause is
- A. Thymoma
- B. Lung cancer
- C Hodgkin's lymphoma
- D. Superior venacaval obstruction
-
151. Which of the following hepatitis viruses have significant perinatal transmission;
- A. Hepatitis E virus
- B. Hepatitis C virus
- C Hepatitis B virus
- D. Hepatitis A virus
-
152. The syndrome of inappropriate antidiuretic hormone is characterized by the following
- A. Hyponatremia and urine sodium excretion 20 meq/
- B. Hypernatremia and urine sodium excretion-20 meg/l
- C. Hyponatremia and hyperkalemia
- D. Hypernatremia and hypokalemia
-
154. A 23-year old woman has experienced episodes of myalgias, pleural effusion, pericarditis and arthralgias without joint deformity over course of several years. The best laboratory screening test to diagnose her disease would be
- A. CD4 lymphocyte count
- B. Erythrocyte sedimentation rate
- C. Antinuclear antibody
- D. Assay for thyroid hormones
-
154. Which of the following is the most common location of hypertensive hemorrhage?
- A. Pons
- B. Thalamus
- C. Putamen/external capsule
- D. Subcortical white matter
-
155. ABsence seizure are characterised in EEG by
- A. 3 Hz spike & wave
- B. 1-2 Hz spike & wave
- C. Generalized polyspikes
- D. Hypsarrythmia
-
156 Commonest presentation of neurocysticercosis is
- A. Seizure
- B Focal neurological deficits
- C. Demennia
- D. Radiculopathy
-
157. Commonest cause of sporadic encephalitis is:
- A. Japanese B Virus
- B. Herpes Simplex Virus
- C Human Immunodeficiency Virus
- D. Rubeola Virus
-
158. Serum total lactate dehydrogenase level will NOT be raised in:
- A. Muscle crush injury
- B. Stroke
- C Myocardial infarction
- D. Hemolysis
-
159. Thiamine deficiency is known to occur in all of the
- following except:
- A. Food Faddist
- B. Homocystinemia
- C. Chronic alcoholic
- D. Chronic heart failure patient on diuretics
-
160. A 30-year old HIV positive patient presents with fever dyspnoea and non-productive cough. Patient is cyanosed. His chest X-ray reveals bilateral, symmetrical interstitial infiltrates. The most likely diagnosis is
- A. Tuberculosis
- B. Cryptococcosis
- C. Pneunocystiscarinii pneumonia
- D. Toxoplasmosis
-
161. A 60-year old man with diabetes mellitus presents with painless, swollen right ankle joint. Radiographs of the ankle show destroyed joint with large number of loose bodies. The most probable diagnosis is:
- A. Charcot's joint
- B. Clutton's joint
- C Osteoarthritis
- D. Rheurnatoid arthritis
-
162. Central nervous system manifestation in chronic renal failure are a result of all of the following, except
- A. Hyperosmolarity
- B. Hypocalcemia
- C. Acidosis
- D. Hyponatremia
-
163. A 25 year old man presented with fever, cough expectoration and breathlessness of 2 months duration. Contrast enchanced computed tomography of the ces showed bilateral upper lobe fibrotic lesions and mediastinum had enlarged necrotic nodes with peripheral rim enhancement. Which one of the following is the mos
- A. Sarcoidosis
- B Tuberculosis
- C Lymphoma
- D. Silicosis
-
164. Cardiac output measured by thermodilution technique is unreliable in all of the following situations except
- A. Ventricular septal defect
- B. Tricuspid regurgitation
- C Low cardiac output
- D. Pulmonary regurgitation
-
165. What is the most characteristic of congenital hypertrophic pyloric stenosis
- A. Affects the first born female child
- B. The pyloric tumour is best felt during feeding
- C The patient is commonly marasmic
- D. Loss of appetite occurs early
-
166. Marjolin's ulcer is a:
- A. Malignant ulcer found on the scar of burn
- B. Malignant ulcer found on infected foot.
- C. Trophic ulcer
- D. Meleney's gangrene
-
167. Bedsore is an example of
- A. Tropical ulcer
- B. Trophic ulcer
- C Venous ulcer
- D. Post thrombotic ulcer
-
168. Early stage of trauma is characterized by
- A. Catabolism
- B. Anabolism
- C Glycogenesis
- D. Gluconeogenesis
-
169. One unit of fresh blood arises the Hb% concentration
- by
- A. 0.1gm%
- B.1gm%
- C. 2gm%
- D. 2.2 gm%
-
170. A 10-mm calculus in the right lower ureter associated with
- proximalhydroureteronephrosis is best treated with:
- A. Extracorporeal shockwave lithotripsy
- B. Antegrade percutaneous access
- C Open ureterolithotomy
- D. Ureteroscopic retrieval
-
171. The best treatment for cystic hygroma is:
- A. Surgical excision
- B. Radiotherapy
- C. Sclerotherapy
- D. Chemotherapy
-
172. Which of the following lasers is used for treatment of benign prostatic hyperplasia as well as urinary calculi?
- A. CO2 laser
- B Excimer laser
- C Ho: YAG laser
- D. Nd: YAG laser
-
173. Semen analysis of a young man who presented with primary infertility revealed low volume, fructose negative ejaculate with azoospermia. Which of the following is the most useful imaging modality to evaluate the cause of his infertility?
- A. Colour duplex ultrasonography of the scrotum
- B. Transrectal ultrasonography
- C. Retrograde urethrography
- D. Spermatic venography
-
174. A 65 year old male smoker presents with gross total painless hematuria. The most likely diagnosis is:
- A. Carcinoma of urinary bladder
- B. Benign prostatic hyperplasia
- C Carcinoma prostate
- D. Cystolithiasis
-
175. A posteriorly perforating ulcer in the pyloric antrum of the stomach is most likely to produce initial localized peritonitis or abscess formation in the following:
- A. Omental bursa (lesser sac)
- B. Greater sac
- C. Right subphrenic space
- D. Hepato renal space (pouch of Morison)
-
176. A 27 year old man presents with a left testcular tumor with a 10 cm retroperitoneal lymph node mass. The treatment of choice is:
- A. Radiotherapy
- B. Immunotherapy with interferon and interleukins
- C. Left high inguinal orchiectomy plus chemotherapy
- D. Chemotherapy alone
-
177. Which of the following is an absolute indication for surgery in cases of benign prostatic hyperplasia
- A. Bilateral hydroureteronephrosis
- B. Nocturnal frequency
- C Recurrent urinary tract infection
- D. Voiding bladder pressures> 50 cm of water
-
178. Which of the following is most suggestive of neonatal small bowel obstruction:
- A. Generalized abdominal distension
- B. Failure to pass meconeum in the first 24 hours
- C. Bilious vomuting
- D. Refusal of feeds
-
179. All of the following conditions may predispose to pulmonary embolism except
- A. Protein S deficiency
- B. Malignancy
- C Obesity
- D. Progesterone therapy
-
180. All of the following are risk factors for deep vein thrombosis (DVT) except.
- A. Duration of surgery more than thirty minutes
- B. Obesity
- C. Age less than forty years
- D. Use of the oestrogen-progesterone contraceptive pills
-
181. If a patient with Raynaud's disease immersed his hand in cold water, the hand will
- A. Become red
- B. Remain unchanged
- C. Turn white
- D. Become blue
-
182. Referred pain from ureteric colic is felt in the groin due to involvement of the following nerve
- A. Subcostal
- B. Iliohypogastric
- C Ilioinguinal
- D. Genitofemoral
-
183. Radiation exposure during infancy has been linked to which one of the follwing carcinoma
- A. Breast
- B. Melanoma
- C Thyroid
- D. Lung
-
184. An increased incidence of cholangiocarcinoma is seen in all of the following except
- A. Hydatid cyst of liver
- B. Polycystic disease of liver
- C Sclerosing cholangitis
- D. Liver flukes
-
185. The Hunterian Ligature operation is performed for
- A. Varicose veins
- B Arteriovenous fistulae
- C Ancurysm
- D. Acute ischemia
-
186. Pseudoclaudication is due to the compression of
- A. Femoral artery
- B Femoral nerve
- C CaudaEquina
- D. Popliteal artery
-
187. Strong correlation with colorectal cancer is seen in:
- A. Peutz-Jegher's polyp
- B. Familial polyposis coli.
- C. Juvenile polyposis
- D. Hyperplastic polyp.
-
188. Sympathectomy is indicated in all following condition
- A. Ischaemic ulcers
- B. Intermittent claudication
- C. Anhidrosis
- D. Acrocyanosis
-
189. The best for surgery of hypospadias is:
- A. 1-4 months of age
- B. 6-10 months of age
- C. 12-18months ofage
- D. 2-4 years of age
-
190. A 50-year old male, working as a hotel cook, has four dependent family members. He has been diagnosed with early stage squamous cell cancer of anal canal. He has more than 60% chances of cure. The best treatment option is
- A. Abdomino-perineal resection
- B. Combined surgery and radiotherapy
- C Combined chemotherapy and radiotherapy
- D. Chemotherapy alone
-
191. In a post operative intensive care unit, five patients developed post-operative wound infection on the same wound. The best method to prevent cross infection occurring in other patients in the same ward is to:
- A. Give antibiotics to all other patients in the ward
- B. Fumigate the ward
- C. Disinfect the ward with sodium hypochlorite
- D. Practice proper hand washing
-
192. A 70 year old male patient presented with history of chest pain and was diagnosed to have coronary artery disease. During routine evaluation, an ultrasound of the abdomen showed presence of gallbladder stones. There was no past history of biliary colic or jaundice. What is the best treatment advice for such a patient for his gallbladder stones
- A. Open cholecystectomy
- B. Laparoscopic cholecystectomy
- C. No surgery for gallbladder stones
- D. ERCP and removal of gallbladder stones
-
193. The nerve commonly damaged during McBurney's incision is:
- A. Subcostal
- B. İliahypogastric
- C. 11th thoracic
- D. 10th thoracic
-
194. A 70 year old patient with benign prostatic hyperplasia underwent transuretheral resection of prostate under spinal anaesthesia. One hour later, he developed vomiting and altered sensorium. The most probable cause is:
- A. Over dosage of spinal anaesthetic agent
- B Rupture of bladder
- C Hyperkalemia
- D. Water intoxication
-
195. What is the most appropriate operation for a solitary
- nodule in one lobe of thyroid
- A. Lobectomy
- B. Hemithyroidectomy
- C. Nodule removal
- D. Partial lobectectomy with 1 cm margin around nodule
-
196. The commonest cause of an obliterative stricture of the membranous urethra is:
- A. Fall-astride injury
- B. Road-traffic accident with fracture pelvis and rupture urethra
- C Prolonged catheterization
- D. Gonococcal infection
-
197. Transient myeloproliferative disorder of the newborn is
- seen in association with:
- A. Tuner syndromo
- B. Down syndrome
- C Neurofibromatosis
- D. Ataxia telangiectasia
-
198. All of the following may occur in Noonan's syndrome except:
- A. Hypertrophic cardiomyopathy
- B. Cryptoorchidisrm
- C. Infertility in females
- D. Autosomal dominant transmission
-
199. A 5 year old boy passed 18 loose stools in last 24 hours and vomited twice in last 4 hour. He is irritable but
- drinking fluids. The optional therapy for this child is:
- A. Intravenous fluids
- B. Oral rehydration therapy
- C. Intravenous fluid initially for 4 hours followed by oral fluids
- D. Plain water ad libitum
-
200. A 15-year old healthy boy with no major medical problem complaints that he breaks out with blocky areas of erythema that are pruritic over skin of his arm, leg and trunk every time within an hour of eating sea foods. The clinical features are suggestive of:
- A. Localised immune-complex deposition
- B. Cell mediated hypersensitivity
- C Localized anaphylaxis
- D. Release ofcomplement C3b
-
201. A 45 day-old infant developed icterus and two dayslater symptoms and signs of acute liver failure
- appeared. Child was found to be positive for HbsAgThe mother was also HBs Ag carrier. The mother's
- hepatitis B serological profile is likely to be
- A. HBsAg positive only
- B. HBsAg and HbeAg positivity
- C. HBsAg and anti-HBe antibody positivity
- D. Mother infected with mutant HBV
-
202. A 2 month old baby with acute viral hepatitis like illnesslips into encephalopathy after 48 hours. The mother isknown hepatitis B carrier. Mother's hepatitis B virusserological profile is most likely to be
- A. HbsAg positive only
- B. HbsAg and HbcAg positive
- C HbsAg and Hbe antibody positive
- D.HBV DNA positive
-
203. A 5 ycar old boy is detected to be HBs Ag positive ono separate occasions during a screening program forepatitis B. He is otherwise asymptomatic. Child wasgiven three doses of recombinant hepatitis B vaccine atthe age of I year. His mother was treated for chrohepatitis B infection around the sane time. The next relevant step for further investigating the child would
- A. Obtain HBcAg and anti-HBe levels
- B. Obtain anti HBs levels
- C. Repeat HBsAg
- D. Repeat another course of Hepatitis B vaccin
-
204. An eight year old boy had abdominal pain, fever withbloody diarhea for 18 months. His height is 100 cmsand weight is 14.5 kg. Stool culture was negative forknown enteropathogens. The sigmoidoscopy wasormal. During the same period, child had an episode ofrenal colic,and passed urinary gravel. The mantoux testwas 5 x 5 mm. The most probable diagnosis is:
- A. Ulcerative colitis
- B. Crohn's disease
- C Interstinal tuberculosis
- D. Strongyloidosis
-
205. A 7 year old girl from Bihar presented with threeepisodes of massive hematemesis and melena. There isno history of jaundice. On examination, she had a largespleen, non-palpable liver and mild ascites. Portal veinwas not visualized on ultrasonography. Liver functiontests were normal and endoscopy revealed esophagealvarices. The most likely diagnosis is
- A. Kala azar with portal hypertension
- B. Portal hypertension of unknown etiology
- C. Chronic liver disease with portal hypertension
- D. Portal hypertension due to extrahepatic obstruction
-
206. Which one of the following statements is false withregard to pyuria in children
- A. Presence of more than 5 WBC/hpf (high powerfield) for girls and more than 3 WBC/hpf for boys
- B. Infection can occur without pyuria
- C. Pyuria may be present without Urinary tractinfection
- D. Isolated pyuria is neither confirmatory nordiagnostic for Urinary tract infection
-
207. Which one of the following statements is false withregard to Xanthogranulomatous pyelonephritis is children
- A. Often affects those younger than 8 years of age
- B. It affects the kidney focally more frequently thandiffusely
- C. Boys are affected more frequently
- D. Clinical presentation in children is same as in adults
-
208. Which one of the following is the most common causeof abdominal mass in neonates?
- A. Neuroblastoma
- B.wilnstumour
- C. Distended bladder
- D.Multicystie dysplastic kidneys
-
209. A ten-year old girl presents with swelling of one kneeint. All of the following conditions can be consideredin the differential diagnosis except
- A. Tuberculosis
- B. Juvenile rheumatoid arthriti
- C Haemophilia
- D. Villonodularsynovitis
-
210. A 1-month old baby presents with frequent vomitingand failure to thrive. There are features of moderatedehydration. Blood sodium is 122 mEq/l and potassiumis 6.1 mEq/1. The most likely diagnosis is
- A. Gitelman syndrome
- B. Bartter syndrome
- C 21-hydroxylase deficiency
- D. 11-p hydroxylase deficiency
-
211. A 40 year old lady delivered a full term baby. Onexamination of the baby, the neonatologist noted certainurogenital abnormality. He took the following picture.The most likely diagnosis is
- A. Urogenital sinus
- B Hypertrophied clitoris
- C. Micropenis
- D. Vulval hematoma
-
212. A 2 month baby presents with history of jaundiceturmeric colored urine and pale stools since birth.
- Examination reveals liver span of 10cms, firm inconsistency and spleen of 3 cms. The most specific
- investigation for establishing the diagnosis would be
- A. Liver function tests
- B. Ultrasound abdomen
- C. Peroperativecholangiogram
- D. Liver biopsy
-
213. All of the following are known risk factors for development ofendometrial carcinoma except
- A. Obesity
- B. Family History
- C Use of Hormone Replacement Therapy
- D. Early Menopause
-
214. A case of Gestational Trophoblastic Neoplasia belongs to high risk group ifdisease develops after
- A. Hyadatidiform mole
- B. Full term pregnancy
- C Spontaneous abortion
- D. Ectopic pregnancy
-
215. A primigravida at 37 week of gestation reported tolabour room with central placenta praevia with heavybleeding per vaginum. The fetal heart rate was normal atthe time of examination. The best management optionfor her is:
- A. Expectant management
- B. Caesarean section
- C. Induction and vaginal delivery
- D. Induction and forceps delivery
-
216. A hemodynamically stable nulliparous patient withectopic pregnancy has adnexal mass of 2.5 x 3 cms andBeta hCG titer of 1500 miu/ml. What modality of treatment is suitable for her:
- A. Conservative management
- B. Medical management
- C. Laparoscopic surgery
- D. Laparotomy
-
217. A 55 year old lady presenting to out patient department(OPD) with postmenopausal bleeding for 3 months hasa 1 x 1 cmnodule on the anterior lip of cervix. The mostappropriate investigation to be done subsequently is
- A. Pap smear
- B. Punch biopsy
- C. Endocervical curettage
- D. Colposcopy
-
218. All of the following drugs are used for management ofpost partumhaemorrhage except:
- A. Misoprostol
- B. Oxytocin
- C. Prostaglandin
- D. Mifepristone (RU-486)
-
219. Laparotomy performed in a case of ovarian tumorrevealed unilateral ovarian tumor with ascities positivefor malignant cells and positive pelvic lymph nodes. All other structures were free of disease. What is stage ofthe disease:
- A. Stage 11 c.
- B. Stage III a
- C. Stage III b
- D.Stage III c
-
220. All of the following may be observed in a normal pregnancy except
- A. Fall in serum iron concentration falls
- B. Increase in serum iron binding capacity
- C. Increase in blood viscosity increases
- D. Increase in blood oxygen carrying capacity
-
221. B Lynch suture is applied on:
- A. Cervix
- B. Uterus
- C. Fallopian tubes
- D. Ovaries
-
222. Pyometra is a complication associated with all of thefollowing conditions except
- A. Carcinoma of the vulva
- B. Carcinoma of the cervix
- C Carcinoma ofendometrium
- D. Pelvic radiotherapy
-
223. Cut-off value of cervical length at 24 weeks of gestationfor prediction of preterm delivery is
- A. 0.5crm
- В 1.5cm
- C 2.5 cm
- D. 3.5 cm
-
224. Pure gonadal dysgenesis will be diagnosed in thepresence of
- A. Bilateral streak gonads
- B. Bilateral dysgenetic gonads
- C. One side steak and other dysgenetic gonads
- D. One side streak and other normal looking gonad
-
225. All of the following are mechanisms of action ofemergency contraception except
- A. Delaying ovulation
- B. Inhibiting fertilization
- C Preventing implantation of the fertilized egg
- D. Interrupting an early pregnancy
-
226. Most common cause of first trimester abortion is:
- A. Chromosomal abnormalities
- B Syphilis
- C Rhesus isoimmunizatiorn
- D. Cervical incompetence
-
227. A hypertensive pregnant woman at 34 weeks comeswith history of pain in abdomen, bleeding per vaginumand loss of fetal movements. On examination the uterusis contracted with increased uterine tone. Fetal heartsounds are absent. The most likely diagnosis is
- A. Placenta praevia
- B. Hydramnios
- C. Premature labour
- D. Abruptio placenta
-
228. A 20 year old woman gives a history of sharp pain the lower abdomen for 2-3 days every month
- approximately 2 weeks before the menses. The mostprobable ctiology for lier pair
- A. Endometriosis
- B. Dysmenorrhea
- C Pelvic tuberculos
- D. Mittelschmerz
-
229. A 55-year old woman has recurrent urinary retentionafter a hysterectomy doen for a huge fibroid. The mostlikely cause is
- A. Atrophic and stenotic urethra
- B Lumbardisc prolapse
- C. Injury to the bladder neck
- D. Injury to the hypogastricplex
-
230. A 45 year old female is having bilateral ovarian massascites and omental caking on CT scan. There is highpossibility that patient is having
- A. Benign ovarian tumor
- B. Malignant epithelial ovarian tumor
- C. Dysgerminoma of ovary
- D. Lymphoma of ovary
-
231. A commonest cause for neuralgic pain in foot is
- A.Compression ofcommunication between medialand lateral planter nerves
- B. Exaggeration of longitudinal arches
- C. Injury to deltoid ligament
- D. Shortening of planter aponeurosis
-
232. A vascular necrosis can be a possible sequelae offracture of all of the following bones, except:
- A. Femur neck
- B. Scaphoid
- C. Talus
- D. Calcanuem
-
233. Kinebock's disease is due to avascular necrosis of
- A. Femoral neck
- B. Medial cuneiform bone
- C Lunate bone
- D. Scaphoid bone
-
234. A classical expansive lytic lesion in the transverseprocess of a 'vertebra is seen in:
- A. Osteosarcoma
- B. Aneurysmal bone cyst
- C Osteoblastoma
- D. Metastasis
-
235. A 30-year old male was brought to the casuallyfollowing a road traffic accident. His physical
- examination revealed that his right lower limb wasshort, intermally rotated, and flexed and adducted at the hip. The most likely diagnosis is
- A. Fracture neck of femun
- B. Trochanteric fracture
- C Central fracture dislocation of hip
- D. Posterior dislocation of hip
-
236. Sciatic nerve palsy may occur in the following injury
- A. Posterior dislocation of hip joint
- B. Fracture neck of femur
- C. Trochanteric fracture
- D. Anterior dislocation of hip
-
237. Osteomalacia is associated with
- A. Decreases in osteoid volume
- B. Decrease in osteoid surface
- C Increase in osteoid maturiation time
- D• Increase in mineral apposition rate
-
238. Which one of the following tests will you adopt whileexamining a knee joint where you suspect an old tear ofanterior cruciate ligament?
- A. Posterior drawer test
- B. Mc Murray test
- C. Lachman test
- D. Pivot shift test
-
239. A 64 year old hypertensive obsese female wasundergoing surgery for fracture femur under gencral
- anaesthesia. Intra-operatively her end-tidal carbondioxide decreased to 20 from 40 mm of Hg, followed byhypotension and oxygen saturation of 85%, whatcould be the most probable cause?
- A. Fat embolism
- B. Hypovolemia
- C Bronchospasm
- D. Myocardial infarction
-
240. In actinomycosis of the spine, the abscess usuallyerodes
- A. Intervertebral disc
- B. Into the pleural cavity
- C Into the reteropritoneal space
- D. Towards the skin
-
241. A 30 year old man came to the outpatient departmentbecause he had suddenly developed double vision. Onexamination it was found that his right eye, when atrest, was turned medially. The most likely anatomicalstructures involved are
- A. Medial rectus and superior division ofoculomotor nerve
- B. Inferior oblique and inferior division ofoculomotor nerve
- C. Lateral rectus and abducent nerve
- D. Superior rectus and trochlear nerve
-
242. The commonest cause of low vision in India is:
- A. Uncorrected refractive errors
- B. Cataract
- C. Glaucoma
- D. Squint
-
243, A recurrent bilateral conjunctivitis occurring with theonset of hot weather in young boys with symptoms ofburning, itching, and lacrimation with polygonal raisedarcas in the palpebral conjunctiva is
- A. Trachoma
- B. Phlyctenular conjunctivitis
- C Mucopuru!ntconunctivitis
- D. Vernal kerato conjunctivitis
-
244. Type IV hypersensitivity to Mycobacterium tuberculosis antigen may manifest as:
- A. Iridocylitis
- B. Polyarteritisnodosa
- C. Phlyctenular conjunctivitis
- D. Giant cell arteritis
-
245. SAFE strategy'" has been developed for the control of
- A. Onchocerciasis
- B. Trachoma
- C. Refractive error
- D. Ocular trauma
-
246. A patient using contact lens develops corneal infection.Laboratory diagnosis of acanthomoeba keratitis was established. The following is the best drug for treatment
- A. Propamidine
- B. Neosporine
- C. Ketoconazole
- D. Polyhexamethylenebiguanide
-
247. In a patient with AIDS chorioretinitis is typicallycaused by:
- A. Cytomegalovirus
- B Toxoplasma gondii
- C. Cryptococcus neoformans
- D. Histoplasmacapsulatum
-
248. A 20 year old man complains of difficulty in reading thenewspaper with his right eye, three weeks aftersustaining a gun shot injury to his left eye. The mostlikely diagnosis is
- A. Macular edema
- B. Sympathetic ophthalmia
- C. Optic nerve avulsion
- D. Delayed viterous hemorrhage
-
249. A child has got a congenital cataract involving the
- visual axis which was detected by the parents right at
- birth. This child should be operated:
- A. Immediately
- B. At 2 months of age
- C. At 1 year of age when the globe becomes normal sized
- D. After 4 years when entire ocular and orbital growth becomes normal
-
250, A lady wants LASIK surgery for her daughter. She asksfor your opinion. All the following things are suitablefor performing LASIK surgery except
- A. Myopia of 4 Diopters
- B. Age of 15 years
- C Stable refraction for 1 year
- D. Coneal thickness of 600 microns
-
251. A patient is on follow-up with you after cnucleation of apainful blind eye. After enucleation of the cyeball, aproper sized artificial prosthetic eye is advised after apostoperative period of
- A. About 10 days
- B. About 20 days
- C 68 wecks
- D. 12-24 wecks
-
252. A one year old child having leucocoria was detected tobe having a unilateral, large retinoblastoma filling half theglobe. Current therapy would involve:
- A. Enuclcation
- B. Chemotherapy followed by local dyes
- C Direct Laser ablation using photo dynamiccryotherapy
- D. Scleral radiotherapy followed by chemotherapy
-
253. FasanellaServan operation is specifically indicated in
- A. Congenital ptosis
- B. Steroid induced ptosis
- C. Myasthenia gravis
- D. Horner's syndrome
-
254. The operation of plication of inferior lid retractors isindicated in:
- A. Senile ectropion
- B. Senile entropion
- C. Cicatricalentropion
- D. Paralytic entropion
-
255. A vitreous aspirate has been collected in an emergencyat 9 pm. What advice you like to give to the staff on duty regarding the overnight storage of the sample:
- A. The sample should be kept at 4°C
- B. The sample should be incubated at 37°C
- C. The sample should be refrigerated in deep freezer
- D. The sample should be refrigerated for the initial3 hours and then incubated at 37°C
-
256. Vortex Vein invasion is commonly seen in:
- A. Retinoblastoma
- B. Malignant melanoma
- C. Optic nerve gliomas
- D. Medullo-epitheliomas
-
257. A 5 year old boy been diagnosed to have posterior superior retraction pocket cholesteotoma. All wouldconstsitute part of the management. except:
- A. Audiometry
- B. Mastoid exploration
- C. Tympanoplasty
- D. Myringoplasty
-
258. A 31 year old female patient complaints of bilateralImpairment of hearing for the past 5 years. On
- examination, tympanic membrane is normal andaudiogram shows a bilateral conductive deafness
- Impedance audiometry shows As type of curve andacoustic reflexes are absent. All constitute part of
- treatment, except
- A. Hearing aid
- B. Stapcdectomy
- C. Sodium fluoride
- D. Gentamicin
-
259. Carharts notch is audiogram is deepest frequency of
- A. 0.5 KHz
- B. 2KHz
- C 4KHz
- D. 8 KHz
-
260. A middle aged male comes to the outer patient department (OPD) with the only complaint of hoarseness ofvoice for the past 2 years. He has been a chronic smokerfor 30 years. On examination, a reddish area of mucosalirregularity overlying a portion of both cords was seen.Management would include all except
- A. Cessation of smoking
- B. Bilateral cordectomy
- C Microlaryngeal surgery for biopsy
- D. Regular follow-up
-
261. Type I thyroplasty is for
- A. Vocal cord medialization
- B. Vocal cord laterlization
- C Vocal cord shortening
- D. Vocal cord lengthening
-
262. A 40 year old male developed persistant oral ulcersfollowed by multiple flaccid bullae on trunk and
- extremities. Direct examination of a skin biopsyimmunoflurescence showed intercellular IgG deposits in
- the epidermis. The most probable diagnosis is
- A. Pemphigus vulgaris
- B. Bullous Pemphigoid
- C Bullous Lupus erythematosus
- D. Epidermolysisbullosaacquisita
-
263. Acantholysis is characteristie of:
- A. Pemphigus vulgaris
- B Pemphigoid
- C. Erythema multoforme
- D. Dermatitis herpetiformis
-
264. A 5 year boy has multiple asymptomatic oval and circularfaintly hypopigmented macules with fine scaling on hisface. The most probable clinical diagnosis is:
- A. Ptyriasisversicolor
- B. Indeterminate lepros
- C Ptyriasisalba
- D. Acrofacialvitiligo
-
265. An eleven year old boy is having tineacapitis on hisscalp. The most appropriatc line of treatment is:
- A.Oral griscofulvin therapy
- B. Topical griseofulvin therapy
- C. Shaving of the scalp
- D.Selenium sulphide shampoo
-
266. The test likely to help in diagnosis of a patient whopresents with an itchy annular plaque on the face is:
- A. Gram's stain
- B. Potassium hydroxide mount
- C. Tissue smear
- D. Wood's lamp examination
-
267. An 8-month old child presented with itchy, exudativelesions on the face, palms and soles. The siblings alsohave similar complaints. The treatment of choice is sucha patient is:
- A. Systemic ampicillin
- B. Topical betamethasone
- C Systemic prednisolone
- D. Topical permethrin
-
268. The most frequent cause of recurrent genital ulcerationin a sexually active male is
- A. Herpes genitalis
- B. Aphthous ulcer
- C. Syphilis
- D. Chancroid
-
269. The syndromic management of urethral dischargeincludes treatment of:
- A. Neisseria gonorrhoeae and herpes genitalis
- B. Chlamydia trachomatis and herpes ganitalis
- C. Neisseria gonorrhoeae and Chlamydia trachomatis
- D. Syphilis and chancroid
-
270. An anaesthetist orders a new attenant to bring the oxygencylinder. He will ask the attendant to identify the correctcylinder by following color code
- A. Black cylinders with white shoulders
- B. Black cylinders with grey shoulders
- C. White cvlinders with black shoulders
- D. Grey cylinder with white shoulders
-
271. Interscalene approach to brachral plexus block does not provide optimal surgical anaesthesia in the area ofdistribution of which of the following nerve
- A. Musculocutaneous
- B. Ulnar
- C Radial
- D. Median
-
272. In all of the following conditions neuraxial blockade isabsolutcly contraindicated, except
- A. Patient refusal
- B. Coagulopathy
- C Severe hypovolemia
- D. Pre-cxisting neurological deficits
-
273. The induction agent of choice is day care anacsthesia is
- A. Sevoflurane
- B. Ketamine
- C. Propofol
- D. Methoxitone
-
274. A 38 ycar old man is posted for extraction of last molartooth under general anaesthesia as a day care case. Hewishes to resume his work after 6 hours. Which one of thefollowing induction agents is preferred:
- A. Thiopentone sodium
- B. Ketamine
- C. Diazepam
- D. Propofol
-
275. Induction agent that may cause adrenal cortexsuppression is:
- A. Ketamine
- B. Etomidate
- C. Propofol
- D. Thiopentione
-
276. During rapid sequence induction of anaesthesia:
- A. Sellick's maneuver is not required
- B. Pre-oxygenation is mandatory
- C Suxamethonium is contraindicated
- D. Patient is mechanically ventilated beforeendotracheal intubation
-
277. At the end of a balanced anacsthesia technique withnon-depolarizing muscle relaxant, a patient recoveredspontaneously from the effect of muscle reiaxantwithout any reversal. Which is the most probablerelaxant the patient had received.
- A. Pancuronium
- B. Gallamine
- C Atracurium
- D. Vecuronium
-
278. A 5 year old boy suffering from Duchenne musculardystrophy has to undergo tendon lengthening procedure.The most appropriate anaesthetic would be
- A. Induction with intravenous thiopentone andN20; and halothane for maintenance
- B.Induction with intravenous suxamethonim and N2O: and oxygen for maintenance
- C.Induction with intravenous suxamethonium and N20: and halothane for maintenance
- D. Inhalation induction with inhalation halothaneand N20; oxygen for maintenance
-
279. A 25 year old male is undergoing incision and drainageof abscess under general anacsthesia with spontaneousrespiration. The most efficient anaestheticcircuiit is
- A. Maplelson A
- B. Mapleson B
- C Mapleson C
- D. Mapleson D
-
280. Which endocrine disorder is associated with epiphysealdysgenesis?
- A. Hypothyroidism
- B. Cushings syndrome
- C. Addison's disease
- D. Hypoparathyroidism
-
281. Fraying and cupping of metaphyses of long bones in achild does not occur in:
- A. Rickets
- B. Lead poisoning
- C Metaphyseal dysplasia
- D. Hypophosphatasia
-
282. High resolution computed tomography of the chest isthe ideal modality for evaluating
- A. Pleural effusiorn
- B. Intersutial lung disease
- C Lung mass
- D. Mediastinaladenopathy
-
283. Which one of the following is a recognized X-Rayfeature of rheumatoid arthritis?
- A. Juxta-articular osteosclerosis
- B. Sacroilitis
- C. Bone erosions
- D. Peri-articular calcification
-
284. Extensive pleural thickening and calcification especiallyinvolving the diaphragmatic pleura are classical features
- A. Coal worker's pneumoconiosis
- B. Asbestosis
- C Silicosis
- D. Siderosis
-
285 CT scan of a patient with history of head injury shows a biconvex hyperdense lesion displacing the grey whitematter interface. The most likely diagnosis is:
- A. Subdural hematoma
- B. Diffuse axonal injury
- C Extradural hematoma
- D. Hemorrhagic contusion
-
286. Which of the following is the best choice to evaluateradiologically a posterior fossa tumor?
- A. CT scan
- B. MRI
- C. Angiography
- D. Myelography
-
287. An eight year old boy presents with back pain and mildfever. His plain X-ray of the dorsolumbar spine reveals asolitary collapsed dorsal vertebra with preserved disc spaces. There was no associated soft tissue shadowThe most likely diagnosis is:
- A. Ewing's sarcoma
- B. Tuberculosis
- C. Histiocytosis
- D. Metastasis
-
288. Most suitable radioisotope of lodine for treatinghyperthyroidism is
- A. I123
- B. I125
- C. I131
- D. I132
-
289. Which of the following radio-isotopes is commonlyused as a source for external beam radiotherapy in thetreatment of cancer patients:
- A. Strontium-89
- B. Radium 226
- C. Cobalt 59
- D. Cobalt-60
-
290. All of the following are impulse control disorders except
- A. Pyromania
- B. Trichotillomania
- C. Kleptomania
- D. Capgras syndrome
-
291. Delirium tremens is characterized by confusionassociated with:
- A. Autonomic hyperactivity and tremors
- B. Features of intoxication due to alcohol
- C Sixth nerve palsy
- D. Korsakoff psychosis
-
292. An alcoholic is brought to the Emergency OPD with the complaint or irrelevant talking. He had stopped usingalcohol three days back. On examination, he is found tobe disoriented to time. place and person. He also hasvisual illusions and hallucinations. There is no historyof head injury. The most likely diagnosis is:
- A. Demctiapraccox
- B. Delirium tremens
- C Schizophreni
- D. Korsakoff's psychosis
-
293. A 41-year old married female presented with headache for the last 6 months. She had several consultations. Allher investigations were found to be within normallimits. She still insists that there is something wrong inher head and seeks another consultation. The mostlikely diagnosis is
- A. Phobia
- B. Psychogenic headache
- C Hypochondriasis
- D. Depression
-
294. A 20-year old man has presented with increased alcoholconsumption and sexual indulgence, irritability, lack ofsleep. and not feeling fatigued even on prolongedperiods of activity. All these changes have beenpresent for 3 weeks. The most likely diagnosis is
- A. Alcohol dependence
- B. Schizophrenia
- C Mania
- D. Impulsive control disorder
-
295. Behavior therapy to change maladaptive behaviors using response as reinforcer uses the principles of
- A. Classical conditioning
- B. Modeling
- C. Social learning
- D. Operant conditioning
-
296. A 15 year old boy feels that the dirt has hung onto himwhenever he passes through the dirty street. Thisrepetitive thought causes much distress and anxiety. Heknows that there is actually no such thing after he hascleaned once but he is not satisfied and is compelled tothink so. This has led to social withdrawal. He spendsmuch of his time thinking about the dirt and contamination. This has affected his studies also. The most likelydiagnosis is
- A. Obsessive compulsive disorder
- B. Conduct disorder
- C. Agoraphobia
- D. Adjustment disorder
-
297. A 50 year old man has presented with pain in back, lackof interest in recreational activities, low mood, lethargydecreased sleep and appetite for two months. There wasno history suggestive of delusions or hallucinations. Hedid not suffer trom any chronic medical illness. Therewas no family history of psychiatric illness. Routineinvestigations including haemogram, renal functiontests, liver function tests, electrocardiogram did notreveal any abnormality. This patient should be treated
- with:
- A. Haloparidol
- B. Sertraline
- C. Alprazolam
- D. Olanzapine
-
298. All of the following are features of hallucinations,except
- A. It is independent of the will of the observer
- B. Sensory organs are not involved
- C. It is as vivid as that in a true sense perception
- D. It occurs in the absence of a perceptualstimulus
-
299. Which of the following symbol represents adopted individuals
-
300. A male child of 15 years, with a mental age of 9 yearshas an IQ of
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