Lecture: Microbes and Antimicrobials

What 3 things = life?
- 1) Metabolism - make most of what you eat
- 2) Regulated Growth - life cycle
- 3) Reproduction
How do we study life? (6)
- 1) Molecular
- 2) Cellular
- 3) Organism
- 4) Evolution
- 5) Ecology
- 6) Behavior
- Remember: MOCBEE
What are microbes?
- - Organisms that are NOT visible to the naked eye
- - Organisms that pass through a stage that is NOT visible to the naked eye ex: worms are visible as adults but NOT as larvae.
context: comparing sizes (... it matters)
put in order from smallest to largest
bacteriophages T4, E. coli, prion, Ebola virus, Human RBC

prion (200nm) < bacteriophages T4 (225nm) < Ebola virus (970nm) < E. coli (3000nm) < RBC (10,000nm)
context: Bacteria morphology
4 major SHAPES
- 1) Coccus - spheres
- 2) Coccobacillus - oval, egg
- 3) Bacillus - rods
- 4) Spirilla - spiral, corkscrew
context: Bacteria morphology
3 types of AGGREGATION and prefix
- 1) pairs (Diplo-) = two's
- 2) clusters (Staph-) = the staff likes to cluster the students together to eat grapes.
- 3) chains (Strept-) = i wear my chains around my neck, where I have my throat - Strep throat.
- gram positive
- LTA (specific): lipoteichoic acid (spans from phospholipid membrane through peptidoglycan)
- Beta 1-4 linkages (NAG-NAM)
- Cross-linking (4 amino acid/4 unit peptide. NAM-NAM)
- Thick peptidoglycan wall

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VASUpharm14

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Lecture: Microbes and Antimicrobials

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IBHS exam 2: Munson. Bonus: lecture material

Updated

2010-09-18T19:52:03Z

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