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Bile salt function
emulsify/cut fat by PHYSICAL digestion, eliminate cholesterol
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Bile salts made where, released from where
made in liver, released from gall bladder
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Enzymes ending in -gen: significance of this particular ending
means that it is deactivated/dormant
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Trypsinogen -> trypsin caused by
enterokinase
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Pepsin -> pepsinogen caused by
bicarbonate, HCO3
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Liver function
- detoxify blood, remove poisonous substances
- stores glycogen, vitamins A, D, B12
- recycles old red blood cells
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Cholecystokinin function
"fat sack movement", move fats in small intestine
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Trypsin function
break down polypeptides into peptides inside of small intestine
made in pancreas in the form of trypsinogen
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Lipase function
breaks down lipids
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Gallstones
bile salts and LDL cholesterol, large crystals that BLOCK the bile duct
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Jaundice - what is it, why it happens
yellowing of skin, bile salts cannot get to gall bladder as the bile duct is blocked - can be caused by gallstones, trauma, etc
bile salts instead go into circulatory system, salts break down red blood cells, red blood cells begin to rot and turn skin yellow
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Small intestine
- 7 m long
- 2.5 cm diameter
- ph of 8
- absorption of nutrients
- three segments: duodenum -> jejunum -> ilium
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Cirrhosis
overloading of liver with any drug
damages liver tissue replaced by non-functioning fat and connective tissue
lack of blood filtration
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Large intestine
- 1.5 m long
- 7.6 cm wide
- zero digestion, absorption of: water, salts, and some vitamins
- stores non-digestible material
- houses E. Coli, which synthesizes vitamin B and K (coenzymes/cofactors)
- Still has lacteals and blood vessels IN CASE some minerals/lipids/fats/proteins are not digested in small intestine WHICH IS EXTREMELY RARE AND SHOULD NOT BE REGARDED AS A PRIMARY FUNCTION
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Lacteal
absorbs fatty acids into lymphatic system
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Capillaries
Transport amino acids, carbohydrates
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Microvilli
increase surface area of villi to increase efficiency of digesting food by increasing chances of food molecules bumping into the villi/microvilli
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Villi
- hair-like structures, take in proteins, lipids
- thin because if it were thicker, more energy is required to transport food
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Gastrin
produces hydrochloric acid
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Lipid digestion
- bile salts are added to aid in digestion
- passive AND active transport; passive = diffusion, active = transporting whatever remains
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Enterogastrone
slows peristalsis so that there is TIME for the food to be absorbed/digested
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Parietal cells
cells on outside of villi (epithelial cells), secrete hydrochloric acid
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Epithelial cells
cells on outside/surface of villi
secrete mucous
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Sphincters of stomach
- esophageal sphincter: between esophagus, stomach
- pyloric sphincter: at bottom of stomach, between stomach and small intestine
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Erepsin
digests proteins from peptides into amino acids
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Amylase
starch/carb digestion
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Prosecretin
- dormant form of secretin
- active form is secretin
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Secretin
secretes bicarbonate
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Appendix function
safehouse for good bacteria
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Erepsin
stage 2 of protein breakdown from peptide into amino acids
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