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Lecture#76 and #77
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what are the 5 cyotskeleton structures
intermediate filaments
microtubules
motor proteins
microfilaments
cell junctions
what call of If for epitheial and appendaes
keratin
what class of If for muscles
Desmin
what type if IF(intermideiate filament) for glial cells
GFAP
what type if IF(intermideiate filament) for mescenchyme
Vimentin
what type if IF(intermideiate filament) for neurons and endothelial cells
neurofilaments and nestin
what type if IF(intermideiate filament) for nucleus cells
lamins
what type if IF(intermideiate filament) for Lens and cataract cells
Filensin and Phakinin
IF characteristics
self assemble
create desmosomes and hemidesmosomes neuro filaments and laminin
what structures are associated with intermediate filamements and what diseases
epidermylysis bullosa (EBS)
epidermilosis hyperkeratiin
muscuar dystropy
hemidesmonsome
desmonsome
neurofilaments
what structures are associated micro dtube and what diseases/diseae medications?
cilia, flagella, and Centrioles
colechine, periwinkle (Vinblastin), Taxol
Motor protein name em
kinesins
dynein
myosin
Kinesins
anterograde movement of stuff from center of cell to the peripherires
two legs
Dynein
retrograde of stuff fromt he peripheries to the center of the cell like mitochondria and golgi memebranes
pogo stick
movement of cilia is based on
presence of denin arms
why are rotatry cili important in embryoeneisis
fetermine left right axis/area based on how they beat
which is faster dynein or kenesin
dnein which isretrograde
why are motor protein like dyenina dn kenisisn important to virology
virus can use motor protetin; hyjack to cary their own viral information
for example herpes virus can stay latent using retrograde transport then reactivate
Microfilaments characteristics
made from gatin assemles to F-actin
polar
require ATP
non self assembly
Wiskott Aldrich Syndrome
there is an X recessive linked mutation int eh actin nucleating factor wasp
what guides axon growth cone
frazzled protein
robo 1
Comm
what does robo do to growth cone
repel growth cones from midline
what does comm do to growth cone
allow growth done to go through midline
what does frazzled do to growth cone
attract growth cone to midline
Human disorderd of axon guidance
mirror synkinesis
corpus callosum dysgenisis
horizontal gaze palsy
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Author
Iana
ID
353434
Card Set
Lecture#76 and #77
Description
physiolgogy cyotoskeleton
Updated
2020-10-08T18:03:52Z
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