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History of Mind
Plato correctly placed mind in the brain. However, his student Aristotle believed that mind was in the heart.Today we believe mind and brain are faces of the same coin. Everything that is psychological is simultaneously biological.
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Phrenology
In 1800, Franz Gall suggested that bumps of the skull represented mental abilities. Though incorrect, his theory did successfully establish that different mental abilities were modular.
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Neuron
Specialized cells that conducts impulses through the nervous system - contains three major parts:
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Cell body
Contains nucleus.Carries out metabolic functions of the neuron
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Dendrites
Branchlike extensions of the cell body.Receive and send messages from other neurons
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Axon
Slender, tail-like extension of the neuron.Transmits signal to dendrites or cell body of other neurons, to muscles, glands, and other body parts
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Myelin Shealth
Covers the axon of some neurons and helps speed neural impulses
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Terminal branches of axon
form junctions with other cells
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Glial cells
Specialized cells in the brain and spinal cord /Hold neurons together/Removes waste (dead neurons) and does clean-up tasks/Performs manufacturing and nourishing activities
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Synapse
Junction where axon terminal of a sending neuron communicates with a receiving neuron across the synaptic cleft
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Resting potential
The slight negative electrical potential of the neuron
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Action potential
Sudden reversal of the resting potential, which initiates the firing of the neuron
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Threshold
Level of depolarization necessary to trigger an action potential/Threshold is all-or-none, like a mousetrap
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Synapse
a junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron. This tiny gap is called the synaptic gap or cleft
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Action Potential
A neural impulse. A brief electrical charge that travels down an axon and is generated by the movement of positively charged atoms in and out of channels in the axon�s membrane.
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Depolarization:
Occurs when positive ions (usually sodium or calcium) enter the neuron, making it more prone to firing an action potential.
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Hyperpolarization:
Occurs when positive ions (usually potassium) leave the neuron, making it less prone to firing an action potential.
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Refractory Period:
After a neuron fires an action potential it pauses for a short period to recharge itself to fire again. The neuron cannot fire an action potential during this period.
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Sodium-Potassium Pumps:
Pump positive ions out from the inside of the neuron, making them ready for another action potential.
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All-or-None Response:
When the depolarizing current exceeds the threshold, a neuron will fire. If the depolarizing current fails to exceed the threshold, a neuron will not fire.
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Whether threshold is barely reached or far exceeded,
the action potential generated is identical
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Intensity of an action potential
remains the same throughout the length of the axon
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Neurotransmitters
Chemical substances released into the synaptic cleft from the axon terminal of a sending neuron/Cross a synapse, /Bind to appropriate receptor sites on dendrites or cell body of a receiving neuron/Influence a cell to either fire or not fire
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Receptors
Protein molecules on surface of dendrites and cell bodies/Have distinctive shapes /Only interact with specific neurotransmitters
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Reuptake
Neurotransmitters taken from the synaptic cleft back into the axon terminal for later use/Terminates the excitatory or inhibitory effect on the receiving neuron
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Lock & Key Mechanism
Neurotransmitters bind to the receptors of the receiving neuron in a key-lock mechanism
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Agonists
Agonist molecule excites similar to neurotransmitters it mimics its effect on the the receiving neuron
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Agonist block neurotransmitter
inhibits. to occupy its receptor site and block its action but not similar enough to stimulate the receptor
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Acetylcholine (Ach)
Causes excitatory effect on skeletal muscle fibers causing them to contract so the body can move
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Norepinephrine
Affects eating, alertness, and sleep
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Epinephrine
Affects metabolism of glucose and causes stored energy to be released during exercise
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Serotonin
Important role in regulating mood, sleep, impulsivity, aggression, and appetite /Primary target of most anti-depressants
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Glutamate
Primary excitatory neurotransmitter in the brain
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GABA
Primary inhibitory neurotransmitter in the brain
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Endorphins
Chemicals produced naturally by the brain that reduce pain and the stress of vigorous exercise/Positively affect mood/Literally means �endogenous morphine�/This means we discovered the drug before we understood how it worked
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Nervous System:
All the body�s nerve cells�an elaborate interwoven network allowing for quick communication.
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Central Nervous System (CNS):
the brain and spinal cord.
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Peripheral Nervous System (PNS):
the sensory and motor neurons that connect the central nervous system (CNS) to the rest of the body
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Peripheral Nerous System
Somatic & Autonomic
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Somatic Nervous System
All sensory nerves /Transmits sense receptor information (eyes, ears, nose, tongue, and skin) to the central nervous system/All motor nerves�voluntary movements/Relays CNS messages to the skeletal muscles of the body
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Autonomic Nervous System
Transmits messages from the brain to the rest of the body/Not under conscious control/Sweating, heartbeat, breathing rate, adrenaline release, etc/Things that are important but that you don�t �decide� to do
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Autonomic 2 parts
Sympathetic & Parasympathetic
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Sympathetic Nervous System
�Fight/Flight�/Mobilizes body during stress and emergencies/Prepares body for action
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Parasympathetic Nervous System
�Rest and digest�/Returns body to normal state after an emergency
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Hindbrain
Pons/ Medulla/ Cerebellum
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Pons
Relays messages between cerebellum and motor cortex/Influences sleep and dreaming
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Medulla
Control center for heartbeat, breathing, blood pressure, swallowing, and coughing/Reticular Formation/Arousal system and activates cerebral cortex
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Cerebellum
Coordinates skilled movement/Regulates muscle tone and posture/Role in motor learning and probably cognition
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Brain Stem
Medulla & Reticular Formation & Thalamus
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The Medulla
is the base of the brainstem that controls heartbeat and breathing.
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Reticular Formation
is a nerve network in the brainstem that plays an important role in controlling arousal
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Thalamus
is the brain�s sensory switchboard, located on top of the brainstem. It directs messages to the sensory areas in the cortex and transmits replies to the cerebellum and medulla
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Cerebellum
the "little brain" attached to the rear of the brainstem. it helpd coordinate voluntary movements and balance
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Forebrain
Thalamus, Limbic System, Corpus callosum
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Thalamus
Relay station between cerebral cortex and lower brain centers
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Limbic System
Group of structures involved in emotional expression, memory, and motivation
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Corpus callosum
Band of nerve fibers that connects the two sides of the brain
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Limbic System
is a doughnut-shaped system of neural structures at the border of the brainstem and cerebrum, associated with emotions such as fear, aggression and drives for food and sex. It includes the hippocampus, amygdala, and hypothalamus
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Thalamus Funtion
Acts as relay station for information in and out of forebrain
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Hypothalamus Function
Controls hunger, thirst, and body temperature; involved in emotions; helps control the endocrine system
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Amygdala Function
A role in emotional responses to unpleasant or punishing stimuli
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Hippocampus Function
Memory storage, navigation, and response to new or unexpected stimuli
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Endocrine System
A system of ductless glands that manufacture hormones and secrete them into the blood stream to affect other parts of the body
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Hormone
Chemical made and secreted in one part and affects another part of the body.
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Pituitary gland � �the master gland�
Controls growth hormone and activates other endocrine glands
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Pineal gland
Secretes hormone that controls sleep/wakefulness cycle
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Cerebrum Componets
Cerebral hemispheres & Corpus callosum & Cerebral cortex
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Cerebral hemispheres
The right and left halves of the cerebrum; they control movement and feeling on the opposite side of the body
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Corpus callosum
The thick band of nerve fibers that connects the two cerebral hemispheres and makes possible the transfer of information and synchronizes activity between the hemispheres
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Cerebral cortex
The gray, convoluted covering of the cerebral hemispheres that is responsible for the higher mental processes of language, memory, and thinking.
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Association areas
Areas of the cerebral cortex that house memories and are involved in thought, perception, and language
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Cerebral Hemispheres
Laterlization, Left hemisphere, & right hemisphere
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Lateralization
Functional specialization of one of the cerebral hemispheres
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Left hemisphere
Controls: Right side of body /Most functions of speech and written language/Coordinates complex movements
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Right hemisphere
Controls left side of body/Specialized for:Visual-spatial perception/Interpreting nonverbal behavior/Right hemisphere damage can cause:/Attentional deficits/Inability to view objects in the left visual field
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Right Brain
controls left side of the body/music processing /emotional thinking /perceiving spatial relations
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Left Brain
Control right side of boy /spoken and written language /numerical skills /reasoning (logic)
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The Split Brain Operation
Rare surgical treatment for severe epilepsy/Corpus callosum is cut, separating the two hemispheres/Each half has separate sensations, thoughts, and perceptions/When picture is shown to the right eye:/Left hemisphere verbally reports what is seen/When picture is shown to the left eye:/Right hemisphere remembers what is seen but can not verbally report it/Can pick out the shown item by touch with left hand/Increased knowledge about lateralization
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Frontal Lobes
Extend from front of brain to skull�s top center/Largest of brain lobes/Contain motor cortex, Broca�s area, & frontal association areas
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Motor cortex
Rear of frontal lobes/Controls voluntary body movement/Participates in learning and cognitive events
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Broca�s area
Control�s production of speech sounds
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Broca�s aphasia
Physical inability to create speech or speech sounds/Caused by damage to Broca�s area
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Frontal association areas
Thinking, motivation, planning, impulse control, emotional responses
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Parietal Lobes
Somatosensory cortex/Body awareness and spatial orientation/Somatosensory cortex /Touch, pressure, temperature, and pain register
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Somatosensory cortex
Front of parietal lobes/Touch, pressure, temperature, and pain register�Wired� to opposite sides of body Affected by experience
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Occipital Lobes
The lobes that are involved in the reception and interpretation of visual information; they contain the primary visual cortex
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Primary visual cortex
The area at the rear of the occipital lobes where vision registers in the cerebral cortex
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Temporal Lobes
Involved in the reception and interpretation of auditory information
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The primary auditory cortex
The part of each temporal lobe where hearing registers in the cerebral cortex
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Wernicke�s area
Language area of the left temporal cortex/Comprehends spoken word, formulates coherent speech, and written language
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Wernicke�s aphasia
Asphasia caused by damage to Wernicke�s area. /Speech is fluent and clearly articulated but doesn�t make sense to listeners
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Temporal association areas
Areas that interpret auditory stimuli
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Neurogenesis and Synaptogenesis
Dendrites and axons grow as synapses develop/Pruning/The process through which the developing brain eliminates unnecessary or redundant synapses
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Myelination
Development of myelin sheaths around axons
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Hemispheric Specialization
Some occurs early in life/Spatial perception occurs around age 8 or so
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Plasticity
Brain�s ability to reorganize or reshape in response to internal and external sources/Brain gains and loses synapses throughout life
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Women have equal amounts of gray and white matter
May explain superior ability to perceive emotions
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Men have more white matter than gray, yet less white matter in left hemisphere
May explain superior ability in spatial tasks
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Navigational information processed in different parts of brain
Women use right parietal cortex and right frontal cortex/Men use left hippocampus/Both use different areas to process location of sound/More studies are needed to look for links between brain differences and actual behaviors.
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EEG � electroencephalogram
Records electrical brain wave activity
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CT Scan � computerized axial tomography
Cross-sectional x-ray images
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MRI � Magnetic resonance imagery
High resolution images w/o x-rays
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Functional MRI
Reveals precise brain structure and activity
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MRI (magnetic resonance imaging)
uses magnetic fields and radio waves to produce computer-generated images that distinguish among different types of brain tissue.
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fMRI (bottom right)
determines active brain regions by measuring heightened blood flow. Here, subject is lying about what cards they have
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PET Scan � positron emission tomography
Reveals brain activity based on blood flow, oxygen use, and glucose consumption
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SQUID � superconducting quantum interference device
Measures magnetic changes in brain when neurons fire
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MEG � magnetoencephalography
Measure magnetic changes showing neural activity within the brain as rapidly as it occurs
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Dominant-recessive pattern
one dominant gene or two recessive genes required for a trait to be expressed
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Multifactorial inheritance
inheritance pattern in which a trait is influenced by both genes and environmental factors
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Polygenic inheritance
many genes influence a particular characteristic like skin color
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Sex linked inheritance
involves genes on the X and Y chromosomes e.g., male or female body type or red-green color blindness
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Behavioral genetics
field of research that uses twin and adoption studies to investigate the relative effects of heredity and environment on behavior
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