Ch 17 Blood

Complications of aplastic anemia generally do NOT include

A) impaired formation of all formed elements
B) bleeding disorders
C) suppressed immunity
D) increase of leukocytes as a result of erythrocyte loss

As red blood cells age _______.

A) they will eventually be excreted by the digestive system
B) iron will be excreted by the kidneys
C) ATP production increases
D) membranes "wear out" and the cells become damaged

Which of the following is a regulatory function of blood?

A) prevention of blood loss
B) delivery of oxygen to body cells
C) transport of metabolic wastes from cells
D) maintenance of normal pH in body tissues

Place the following in correct developmental sequence:

reticulocyte, proerythroblast, normoblast, late eryththroblast 

A) 2, 1, 3, 4
B) 1, 3, 2, 4
C) 2, 4, 3, 1
D) 1, 2, 3, 4,

James has a hemoglobin of 16 mg/100 ml blood. This is______. 

A) within normal range
B) abnormally low
C) above normal
D) normal only if James is an infant

Which of the below is the parent cell for all formed elements of blood?

A) megakaryocyte
B) polymorphonuclear cell
C) pluripotent stem cell (hemocytoblast)
D) NK cell

Which of the following is NOT a cause of bleeding disorders?

A) vitamin K deficiency
B) defect in the clotting cascade
C) thrombocytopenia, a condition of decreased circulating platelets
D) excess secretion of PDGF

The slowest step in the clotting process is ______. 

A) release of PF3
B) production of fibrin strands
C) formation of prothrombin activator
D) binding of fibrin strands

Blood is a ______.

A) suspension
B) heterogeneous compound
C) colloid
D) homogeneous compound

Which blood type is called the universal donor?

A) B
B) AB
C) O
D) A

All of the following conditions impair coagulation EXCEPT _____. 

A) vitamin K deficiency 
B) liver disease
C) severe hypocalcemia
D) vascular spasm

Which of the following is a protective function of blood?

A) prevention of blood loss
B) maintenance of adequate fluid volume
C) maintenance of normal pH in body tissue
D) maintenance of body temperature

Which of the following is true about blood plasma?

A) the main protein component is hemoglobin
B) it is about 90% water
C) it is the same as serum but without the clotting proteins
D) is contains about 20 dissolved components

When neither anti-A nor anti-B serum clot on a blood plate with donor blood, the blood type is ____. 

A) A
B) O
C) AB
D) B

NO visible cytoplasmic granules are present in _____.

A) neutrophils
B) basophils
C) eosinophils
D) monocytes

When can erythroblasosis fetalis NOT possibly happen in the child of an Rh- mother?

A) if the child is Rh+
B) if the child is O+
C) if the father is Rh-
D) if the father is Rh+

What organ in the body regulates erythrocyte production?

A) kidney
B) liver
C) brain
D) pancreas

A lack of intrinsic factor leading to a deficiency of vitamin B12 and large pale cells called macrocytes is characteristic of ___. 

A) sickle cell anemia
B) aplastic anemia
C) pernicious anemia
D) polycythemia

Blood volume resotrers include all of the following EXCEPT______.

A) albumin
B) saline solution
C) packed cells
D) dextran

Which of the following is an incorrect or false statement? 

A) Unique to the ABO blood group is the presence in the plasma of preformed antibodies.
B) Blood typing for Kell, Lewis, and Duffy factors is always done before a blood transfusion.
C) When a transfusion reaction occurs, the oxygen carrying capacity of the transfused blood cells is disrupted and the clumping of RBCs in small vessels hinders blood flow to tissues beyond those points.
D) Transfusion of incompatible blood can be fatal.

Which of the following is a pivotal molecule associated with the external surfaces of aggregated platelets and is involved in the intrinsic and extrinsic mechanisms of blood clotting?

A) Thromboplastin
B) Thrombin
C) PGI2
D) PF3

A) 1,2,3,4
B) 3,2,1,4
C) 3,4,1,2
D) 4,3,1,2

The most abundant plasma protein is ____. 

A) clotting protein
B) albumin
C) bile
D) globulin

Which of the following might trigger erythropoiesis?

A) moving to a lower altitude
B) decreased tissue demand for oxygen
C) hypoxia of EPO- producing cells
D) increased number of RBCs

Sickling of RBCs can be produced in those with sickle cell anemia by _______. 

A) vigorous exercise
B) travel at high altitude
C) travel at high altitude and vigorous exercise
D) malaria and travel at high altitude

An individual who is blood type AB- can _____.

A) donate to all blood types
B) donate to types A, B, AB, but not O
C) receive types A, B, and AB but not O
D) receive any blood type in moderate amounts except that with the Rh antigen

What is the average pH range of blood?

A) 8.35- 8.45
B) 7.75- 7.85
C) 7.35- 7.45
D) 4.65- 4.75

Thromboembolic disorders______.

A) include thrombus formation, a clot in a broken blood vessel
B) include embolus formation, a clot moving within the circulatory system
C) result in uncontrolled bleeding
D) are caused by vitamin K deficiency

All of the following can be expected with polycythemia EXCEPT_______. 

A) high hematocrit
B) increased blood volume
C) low blood viscosity
D) high blood pressure

Which of the following is characteristic of all leukocytes?

A) They are phagocytic.
B) They are nucleated. 
C) They have cytoplasmic granules.
D) They are the most numerous formed element in blood. 

Which statement is correct regarding blood cell formation?

A) Red marrow is the main site of blood cell formation throughout adult life.
B) Before the seventh month of fetal development, yellow marrow is the main site of blood cell formation.
C) Yellow marrow is the main site of leukocyte formation.
D) The main sites of blood cell production in adults are the spleen and the liver.

Fred's blood was determined to be AB+. What does this mean?

A) There are no antibodies to A, B or Rh antigens in the plasma.
B) He can only receive blood from a donor who is AB+.
C) His blood lacks Rh factor.
D) Antibodies to A and B are present in the red cells.

Which of the following is NOT a phase of hemostasis?

A) fibrinolysis
B) platelet plug formation
C) coagulation
D) vascular spasm

Platelets____.

A) are the precursors of leukocytes
B) stick to the damaged area of a blood vessel and help seal the break
C) have a life span ~120 days
D) have multiple nuclei

The special type of hemoglobin in fetal RBCs is ____.

A) hemoglobin A
B) hemoglobin B
C) hemoglobin S
D) hemoglobin F

Which of these is NOT a normal plasma protein?

A) gamma globulin
B) fibrinogen
C) albumin
D) thromboplastin