Lecture review

  1. What are the naming conventions in regards to D and L and α and β  for sugars
    • If it is a 6 member-ed ring α will have the OH of the anomerica carbon above the plane of the figure and the β below the plane of the figure
    • 5-member-ed rings are the opposite.
    • α is below and β is above
    • Further more the D form must be the mirror image of the L form and vice versa.
  2. What signals lysosome degradatiin in glycoproteins
    phosphorylated mannose
  3. Insulin active what type of enzymes ?
    phosphotases- remove or dephosphorylate
  4. What are the three reversible reactions of the glycolysis  and what do they do ?
    • Step 1- hexokinase 
    • Phosphorylated glucose to G6P 
    • step 3- phosphofructokinase 
    • creates F16bisphosphate from fructose6P 
    • Step 10 - Pyruvate dehydrogenase
    • converts PEP to Pyruvate
  5. W Hat is the commuted step of Glycolysis ?
    • Step 3
    • PFK-1
  6. Whats stimulate step 3 the committed step ?
    • Insulin
    • F26bisphospate 
    • F16) via positive feedback 
    • AMP
    •  all of which get rid of phosphate on the PFK-1
  7. What is the significance of PFK-2
    • found in the liver 
    • regulated by the pancretic enzymes
  8. What events are happening/increase  when insulin is high?
    • glycolysis
    • glycogenisis 
    • fatty acid synthesis 
    • PFK-1 and 2 is on
  9. What is FBPhase?
    enzyme that dephosphorylates F26Bisphospahates thus need to be off to increase glycolysis
  10. What is the Pasteur effect
    The slowing of glycolysis in o2
  11. Gram positive bacteria
    • pneumonia 
    • chlamydia 
    • Histoplasmosis
  12. Gram negative bacteria
    • Legionellea
    • Ecoli 
    • typhoid fever 
    • Gonoccocus ( gonereah )
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Lecture review
sugar, sugar !