-
comp inhib
- inhib binds to AS
- can be overcome by increasing sub conc
- Vmax same, Km increases
-
non-comp inhib
- inhib binds to allosteric site and modifies enzyme so it won't catalyze rxn
- Vmax decrease, Km same
-
uncomp inhib
- binds to allo sites of substrate-enzyme complexes
- vmax decrease, Km decrease
-
mixed-type inhib
- inhib can bind to allo site of empty enzyme or enzyme-sub complex
- Vmax decreases, Km depends on affinities
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