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What is cancer?
Excessive growth of cells that lack the capability of normal cellular function
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In normal cell division, cell division stops when normal cells _____ _____ ____
Surround normal cells
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Cancer cells form a mass called a ____
Tumor
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____cells form when the body doesn’t need them and they don’t die. They lack contact inhibition
Cancer
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Cancer cells lack _____ _____
Contact inhibition
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: new growths of abnormal tissue.
Neoplasm
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Not all neoplasms contain _____ cells
Cancer
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What are the two types of neoplasms?
Benign and malignant
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: non cancerous cells and non recurrent
Benign
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: cancer cells that are unlimited in forethought. May lead to metastasis ( spreading)
Malignant
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Cancerous tumors have to be _____ or ____ I’m size to bed detected
1cm, 1/2 inch. (2.2 cm = 1 inch)
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: irregular borders, immovable, and recurrence is common.
Malignant tumors
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An organ containing a ___ tumor can usually function as usual without complications. (Unless size interferes with function;swallowing, breathing, blood flow etc)
Benign
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An organ containing a _____ tumor will eventually be effected and it’s function will be altered.
Malignant
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: the spread of a tumor from the primary side to a different area or distant part of the body
Metastasis
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Metastasis can occur by three means : 1.________, 2._______,3.______
1. Invade blood or lymph 2. Move by mechanical means 3. Lodge and grow in new location
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______ tumors carry with them the cell characteristics of the original tumor( lung tissue found in brain tissue)
Metastic tumors
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_____ simply means that a tumor is contained within one area
In situ (localized)
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: normal cells become altered or damaged due to carcinogen exposure
Initiation
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: repeated exposure to carcinogens that cause cells to mutate
Promotion
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: after promotion, further mutation occurs from carcinogen exposure
Progression
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Name some risk factors for cancer
Smoking, asbestos, high fat-low fiber diet, radiation (sunlight), hormones (estrogen), immune factors, and genetics
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: cancer of skin and organs with lining( lungs, colon, etc.) most common type
Carcinoma
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: cancer of the blood, bone, cartilage, and adipose tissue
Sarcoma
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: cancer of the lymph nodes or spleen
Lymphoma
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: cancer of the bone marrow.
Leukemia
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: cancer cells that produce skin pigment
Melanoma
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Most common cancers in men are
Prostate, lung, and colon
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Most common cancers in women are
Breast, lung, and colon
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Women’s Pap testing should be done no later than age
21
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Women who are 30-65 yo should have a Pap smear with an HPV test every ____ years
5
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Mammography should be done once every 1-2 years in anyone older than ___
45
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After age 65, a woman who has had __ normal paps in a row within the past 10 years can choose to stops screaming
3
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Pickled and smoke food are a risk for ___
Cancer
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A ____ must be done to diagnose cancer
Biopsy
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A increase ____ ____ can indicate bone metastasis
Serum calcium
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Tumor markers such as_____ and _____ hell monitor tumor response and progress of treatment not the progression.
PSA and CEA
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: stage of cancer where malignant cells are confined to tissue of origin with no signs of mets
Stage I
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: stage of cancer with limited spread of cancer to local area generally to are of lymph nodes
Stage II
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: stage of cancer where the tumor is larger and probably has invaded surrounding tissue
Stage III
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: stage of cancer where cancer has invaded and metastasized to distant parts of the body
Stage IV
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TNM system
Tumor size (1-4) Nodes ( node involvement) 0-3 Metastasis (0 or 1) 1 being positive and 0 being none
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: type of surgery when entire tumor is removed
Curative
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: surgery done for pain purposes and control symptoms( not a cure)
Palliative
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: mole or polyp removal
Prophylactic surgery
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_____ radiation allows for higher doses without destroying surrounding tissues
Internal radiation
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_____ radiation bean radiation is used to destroy cancer cells with minimal damage
External radiation
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_____ radiation does not cause the patient to be radioactive
External
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_____ radiation causes a person to be radioactive
Internal
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: administration of radiation distributed through the patients body.
Internal Unsealed radiation
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Internal unsealed radiation is administered per ___ and ____
IV, and oral
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: administration of radiation into hollow cavity. Delivers continuously over hours or days.
Internal Sealed radiation implant
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Internal sealed radiation can be used for ____,____,and _____ cancer
Vertical, uterine, and prostate
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A nurse should spend less than ___ hr with radioactive patient
1
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With internal radiation therapy, visitors are limited to ____min, standing as far away from site as possible
10 min
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Prevent dislodgment of the sealed radiation implant from cavity through _______ and _____
Strict med rest and minimal moving from side to side
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If vagina radiation implant, keep legs
Closed and straight
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If patient is receiving sealed radiation do not bathe
Below waste
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____ will be in place to keep bladder from exposure to radiation and because of strict bed rest
Foley catheter
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With a person receiving sealed radiation , do not raise HOB more than ____ to prevent dislodgment
30 - 45 degrees
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With sealed implant keep long handled forceps and a ___ container at bed side
Lead
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Check placement of sealed implant by checking the ___
Threads
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If sealed implant falls out
Call radiologist and do not touch the implant
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After internal sealed radiation implant removal 1.________2.______3.______
1.Perform good peri care ( enema or douche may be ordered. 2. Pt is no longer radioactive 3. It is normal for pt to experience Oder from vaginal discharge and discoloration
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External radiation can be very drying to skin, you should use ___ based lotions approved by HCP.
Water
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Pt receiving external radiation should avoid 1.______2._______3._____
1. Lying on effected side or area. 2. Tight clothing 3. Sun exposure
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___ markings are required for external radiation and should NOT be removed
Skin
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External radiation treatment are relatively less than ___ mins
5
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: affects the cells that rapidly divide and reproduce ( normal cells of GI, oral cavity, hair follicles, and bone marrow)
Chemotherapy
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Avoid __ and ___ because pectin can contain bacteria
Fresh fruit and flowers
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All malignant cells must be _____ in order for cancer to be cured
Destroyed
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Routes of chemotherapy administration
Oral, IV, IM, topical
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Better result of cancer treatment are usually achieved with ______ therapy vs. single agent
Combination therapy
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______ is given in a series of cycles to allow for recover of normal cells and to destroy more of the malignant cells
Chemotherapy
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Most chemo regimens are every ___ weeks
3 weeks
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Chemo therapy cycles are utilized to give blood counts the chance to ____________
Build back up
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Many different classes of chemotherapy drugs are available but they all have the same goal which is
Attacking and killing cancer cells
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All chemotherapies have an effect on ___ cells and _____ cells
Normal and malignant
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: an oral chemotherapy medication that causes red irons, loss of hair, N/V, cardiac damage, vesicant (blistering)
Adriamycen
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: oral chemotherapy medication that causes hair loss, neuropathy, and muscle aches
Taxol
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:oral chemotherapy medication that causes SOB, cough, and pulmonary fibrosis.
Bleomycin. **ASSESS FOR RESPIRATORY SIDE EFFECTS****
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: used to treat blood disorders caused by chemo by stimulating the production of blood cells
Colony stimulating factors
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: Epogen, Epoetin Alpha, Procrit- stimulates RBC production
Erythropoietin
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: Neumega (Oprelvekin) - stimulates WBC production (platelets)
Imterleukin-11
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Because colony stimulating factors are proteins do not ___ or ___ container
Refrigerate or shake
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: Leukine (Sargramostin)- stimulates WBC production
GM-CSF (Granulocyte Colony- stimulating factor)
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: Neupogen, Neulasta (Filgrastim, Pegfilgrastim)- stimulates WBC production
G-CSF (Granulocyte Colony stimulating factor)
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What is the most serious side effect of chemo therapy?
Bone marrow depression
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What are the side effects of chemotherapy?
•Bone marrow depression. •Leukopenia. • Thrombocytopenia. • Anemia. •N/V, Diarrhea •Stomatitis (inflammation of the mouth. • Alopecia •Sepsis •Memory lapses •Reproductive problems
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Chemotherapy patient teaching
Small frequent meals, fluids between meals, avoid greasy, spicy or odorous foods, bland diet, carbonated drinks may help relieve nausea
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Most common ant-metics given to chemo patients
Zofran, Compazine, Kyttol, and Aloxi
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If a patient has stomatitis they should use a neutral mouth wash of ____,____, and ____
- Salt, baking soda, and water
- (Or Benadryl and water)
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___ ____ May prevent hair falling out in patients undergoing chemo
Ice caps (freezes the hair follicle)
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What are some Reproductive alterations that may happen for a patient under going chemo
•painful intercourse • decreased sex drive •infertility •erectile dysfunction
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“Chemo fog” memory lapse, trouble concentratin, unable to multitask, or remember details
Neurotoxicity
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Chemo treatment is with heals if blood counts are too ___
Low
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Never use a ____ or ____ to clean up chemo medication
Towel or wash cloth
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B.I.T.E.S.
Bleeding Infection Tiredness Emesis Skin changes
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Bleeding suggests _____ _____
Low platelets
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Infection suggests low____ and risk for _____
WBC, infection
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Tiredness suggests ____
Enemia
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Emesis suggests altered ______ and electrolyte——-
Nutrition, imbalance
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Skin changes suggests _____ reaction or skin ____
Radiation , break down
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The 3 ongoing care needs for a patient that begins at the diagnosis of cancer
1. Medical 2. Physical 3. Psychosocial
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Hospice care patients have to have less than a ____ month prognosis
6
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Hospice cares goal is to keep patient ______ and to promote
Comfortable , Quality of Life
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What are the stage of grieving/death and dying.
Denial. Anger. Bargaining. Depression. Acceptance.
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: fluid around the heart s/s edema, SOB
Pericardial effusion
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: seen in patients with bone metastasis to spine. S/s sever low back pain and most often lose the use of their legs
Spinal Cord Compression
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: most common in lung cancer patients, large tumor that blocks blood flow through vena cava s/s high pitch voice, edema of head and neck, seizures
Superior Vena Cava Syndrome
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: most often see with patients with bone metastasis. The calcium leaves bone due to disease and deterioration and enters into the circulatory system s/s calcium level over 11, confused, disoriented
Hypercalcemia
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If patients calcium levels get too high they can go into a ___
Coma
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