part 2

g1
- Orcs are binding
- helicases are loaded
- nothing is active yet until S phase
Origin of RC

identify and bind to origins of replication
Pre-replication complex
- includes: ORC, helicase loader, MCM
- orc: provides the foundation to start transcription
- helicase loader: help position the helicase (Cdt1, cdc6)
FUNCTION: position helicases @ origins of replication
geminin

block helicase loading

Author

user011

351332

Card Set

part 2

Description

Updated

2020-03-25T20:33:06Z

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