Some points about Respiratory burst
•Oxygen dependent killing is largely mediated through reactive oxygen intermediates. ▪Superoxide anion (O2) ▪Hydrogen peroxide (H2O2) ▪Hydroxyl radical (OH) ▪Hypochlorite (HOCl)
•The generation of reactive oxygen intermediates is due to Rapid activation of NADPH oxidase.
•Catalase , Superoxide dismutase and Glutathione peroxidase are all Radical scavenging enzymes that prevent Oxygen mediated injury.
Drugs that can be eliminated by
Alkaline diuresis : [@ PSC LIMB]•Salicylates •Barbiturates (long acting) •Chlorpropamide •Methotrexate •Primidone •Lithium & Isoniazid (Controversial)
Acid Diuresis : [@ Q PAS]•Amphetamine •Quinine •Phencyclidine •Strytchnine
Pseudo fracture is seen in
Osteomalacia
Also known as ▪Milkman's fracture ▪Pseudofracture ▪Looser's zone ▪Osteoid seams
Maternal serum AFP
Increased in ▪Wrong gestational age ▪Open neural tube defects and anencephaly ▪Multiple pregnancy ▪Anterior abdominal wall and renal anomalies ▪Fetal bladder tumors
Decreased in ▪Downs syndrome ▪Gestational Tropoblastic disease
Most common
•Grey matter degenerative disease : Alzheimer's disease•Etiology for temporal lobe epilepsy : Gangliogliomas•Causative agent causing Acute pyogenic Meningitis in adults : S. Pneumoniae•Causative agent causing Neonatal pyogenic Meningitis : E.Coli
Antidotes
Acids : β-aminoproprionitrile *Alpha adrenergics : Phentolamine *Amantins : Benzyl penicillin *Arsenic : Dimercaprol , Unithiol *Beryllium : Aurintricarboxylic acid, Sodium salicylateBeta adrenergics : PropanololBeta blockers : Glucagon , IsoprenalineBotulism : Guanidine *CO : Hyperbaric oxygen , TocopherolCentral anticholinergics : PhysostigmineChloroquine : DiazepamCholinergic agents : AtropineCopper : Penicillamine , Trientine *Couramin derivatives : Vitamin KCyanide : Amyl nitrate , Dicobaltedetate , Hydroxocobalamine , Sodium nitrate , Sodium thiosulphate. *Cyanide , CO , H2S : OxygenDigitalis : Digoxin specific antibody fragmentsErgotism : Sodium nitroprusside *Iron , Aluminum* : Desferrioxamine Lead , mercury : Succimer *Mercury : N-Acetyl penicillamine * , BALMethanol , Ethylene alcohol : Ethanol , 4-methylpyrazole *Organic peroxides : Ascorbic acid *OP : OximesOxalates , Fluorides : Calcium saltsPCM : N-Acetyl cysteine , Methionine*Peripheral anticholinergics : NeostigmineRadioactive metals : Pentetic acid *Thallium : Potassium hexacyanoferrate *Methyl alcohol : Ethanol / FomepizoleEthylene glycol : FomepizoleBelladona poisoining : Physostigmine
Most common
Agent causing naive valve IE : S. AureusHypergonadotropic hypogonadism : Klinefelter's syndromeChronic Hypercalcemia : 1° hyperthyroidismRespiratory hypoxia : V-P mismatchHistologic response to hepatotoxic stimuli : Fatty liverHypocalcemia : Impaired PTH or Vit D productionPattern of IBD : Constipating alternating with diarrhoea.Glycolytic defects a/w exercise intolerance : Mc Ardle's or Myophosphorylase deficiencyPredisposing condition for subdural empyema : SinusitisIndicaton for liver transplantation : 1° sclerosing cholangitisClinical sign of renal disease in lupus nephritis : ProteinuriaCause of sensory gangliopathies : Sjogrens syndrome , Paraneoplastic diseaseHereditary neuropathy : Charcot marie tooth diseaseExtraarticular manifestation of Ankylosing spondylitis : Acute anterior uveitisForm of peripheral neuropathy a/w HIV : Distal symmetric PolyneuropathyCranial mononeuropathies : 7th > 3rd > 6th CNPeripheral neuropathy in developing countries : LeprosyIndication for surgery in Ankylosing spondylitis : Severe hip joint arthritisCause of renal failure in septic shock : ATNLytic lesions in MM : Vertebra > Ribs > SkullSite of COA : Distal to origin of SCACause of nephrotic range proteinuria : membranous nephropathy / DMFeature of aortitis in CXR : Calcification of Ascending aortaBlood transfusion reaction : Febrile non hemolytic reaction.Location of brain abscess in Cyanotic heart disease : Frontal > ParietalCNS tumour a/w NF-1 : Optic nerve glioma Symptom of alcohol withdrawl : HangoverSign of alcohol withdrawl : TremorSequelae d/t Periventricular leukomalacia : Spastic diplegiaCause of acute RVF : Acute Cor-Pulmonale / PECause of Renal artery stenosis in children in india : Takayasu arteritisCause of Renal artery stenosis in children in west : Fibromuscular dysplasiaCause of Renal artery stenosis in older patients : AtherosclerosisAffected organ in amyloidosis : Kidney > HeartForm of localized amyloidosis : Aα amyloidosisForm of xeroderma pigmentation : Absence of UV specific endonucleaseRenal lesion in leprosy : Membranous GlomerulonephritisPathological findings in nephrogenic DM : Diffuse glomerulosclerosisNon epidemic meningoencephalitis in immunocompetent individuals in US : Herpes EncephalitisSubcortical degenerative disease : ParkinsonismPresenting symptom of Osler weber Rendu syndrome : HemoptysisMycotic Pneumonia in AIDS patient : CryptococcusOrganism causing pyogenic meningitis in infants & children : N. MeningitisMotor neuron disease : ALSOppourtinistic infection in AIDS : ToxoplasmosisLysosomal storage disease : Gaucher's diseaseManifestation of asbestosis exposure : Pleural plaquesAsbestos related pleural disease : Pleural effusionSystemic vasculitis in adults : GCA Hereditary hypercoagulable condition : Factor V leidenHereditary leukodystrophy : Metachromatic leukodystrophyFluid collection seen in transplant patients : LymphocelesForm of AS : ValvularForm of HOCM : Asymmetric involvement of interventricular septum.Cerebral mass lesion in AIDS : ToxoplasmosisChest radiograph finding in Acute Pulmonary embolism : AtelectasisCollagen disorder for a pleural effusion : SLEOrganism causing acute pyogenic Meningitis in adults : S. PneumoniaeOrganism causing acute pyogenic Meningitis in neonates : E. ColiEtiology of chronic temporal lobe epilepsy : GangliogliomasDiffuse grey matter degenerative disease : Alzheimer's diseaseCardiac manifestation of SLE : Pericarditis (Not Libman sack's endocarditis)Aortic branch involved in Takayasu arteritis : Left subclavian arteryAcute Complication of hemodialysis : HypotensionAbnormality in ECG in PE : Sinus tachycardia (Not S1Q2T3 pattern)Cause of acute hepatitis : Hepatitis ECongenital bleeding disorder : Von Willebrand diseaseCause of death in Marfan syndrome : Dilatation of aortic rootCausative agent of endocarditis following placement of permanent pacemaker : S. AureusCause of TR : Dilatation of Rt. VentricleCause of CAP : PneumococcusDeath in diptheria : Toxic cardiomyopathyDeath in measles : PneumoniaCause of sudden death in Sarcoidosis : ArrythmiaType of RCC : Clear cell CaSite of metastasis in RCC : LungsCause of poststernotomy osteomyelitis : S. AureusCause of death in Menke's disease : Cardiac ruptureArrythmia in ICU patients : AFArrythmia in pts with cardiac arrest : VFArrythmia in COPD : Multifocal atrial tachycardiaSustained Arrythmia : AFBenign rhythm : Atrial premature contractionMechanism of arrythmia : ReentryAssociated Arrhythmia with alcohol binge in alcoholic : Atrial fibrillation > Atrial flutter > Ventricular premature contraction.Cause of pleural effusion in AIDS patients : Kaposi sarcomaType of pitutary adenoma : ProlactinomaGene mutation in beta Thalassemia : Intron 1 inversionFoodborne outbreaks worldwide : S. AureusCause of Cystitis : E. Coli
DOC for
Necrotising fascitis : Clindamycin + Vancomycin + GentamycinAcne : ClindamycinAcute HCV infection : Ribavirin + INF-αAcute meningococcal pyogenic Meningitis : CP GAcyclovir resistant herpes : FoscarnetAnthrax : CiprofloxacinAntifungal prophylaxis : FluconazoleAsymptomatic intestinal amoebicides : Diloxanide furoateBrucellosis : Rifampicin + DoxycyclineCAP with cardiopulmonary infections : FQ / beta lactams + Macrolides / doxyChagas disease : NifurtimoxChlamydal infection in pregnancy : ErythromycinChloroquine resistant F.malaria : QuinineChloroquine resistant F.malaria in pregnancy : QuinineChronic HBV : Lamivudine + INF alphaChronic HBV (newer drugs) : EntacavirCryptococcal Meningitis : Amphotericin BEarly african sleeping sickness : SuraminEnterobacter , Klebsiella , Actinobacter : CarbapenemExo-erythrocytic stage of malaria : PrimaquineGut sterilization in Hepatic Encephalopathy : NeomycinHerpes labialis : DocosanolHydatidosis : AlbendazoleInvasive aspergillosis : VoriconazoleLate African sleeping sickness : MelarsoprolMalaria in pregnancy : ChloroquineMelioidosis : CeftazidimePapilloma virus : CidofovirPleurodesis in malignant effusion : DoxycyclinePulmonary MDR-TB : BedaquilineRadical cure of P.vivax malaria : Primaquine Relapsing fever : DoxySuperficial mycosis : KetoconazoleSurgical prophylaxis : CefazolinSystemic mycosis : ItraconazoleTopical keratoconjunctivitis by HSV : IdoxuridineTopical treatment of impetigo : RetapamulinToxoplasmosis in pregnancy : SpiramycinTularemia : StreptomycinProphylaxis of Meningococcal meningitis : RifampicinStrongyloides : IvermectinGTCS / Atonic / Absence / Myoclonic epilipsy : ValporatePartial seizure : CarbamazepineGeneralized Pustular psoriasis : Methotrexate (Pregnancy → Steroids)Acute Iridocyclitis : AtropineNausea in pregnancy : Doxylamine & PyridoxineAntiepilleptic in pregnancy : PhenobarbitoneEssential thrombocytosis : HydroxyureaNight terrors : DiazepamLymphadema : PenicillinPustular psoriasis : RetinoidsAntidiabetic in obese patients : MetforminCML : ImatinibDiarrhoea in AIDS : OcrreotideMania with dysphoria (Mixed mania) : ValporateMania with psychosis : Valporate with Olanzapine or risperidone.Typhoid carriers : Ampicillin or AmoxicillinBier's block : LidocaineFor pneumonic plaque : StreptomycinChemoprophylaxis of Pneumonic plaque : TetracyclinePlaque meningitis , pleuritis , endopthalmitis and myocarditis : ChloramphenicolBelladona poisoining : PhysostigmineAllergic Bronchopulmonary aspergillosis : Prednisolone [New recommendation → Itraconazole]Clostridium : lV penicillin + ClindamycinListeria : IV Ampicillin or penicillinKlebsiella : CarbapenemCampylobacter : ErythromycinY.Pestis : StreptomycinPertusis : ErythromycinBrucella : StreptomycinMycoplasma : ErythromycinCHF in Paediatric age group : ACE InhibitiorsPrimzmetal angina : NitratesOrthostatic hypotension : MidodrineAkathesia : PropanololIntractable hiccups : ChlorpromazineFor treatment of plaque : StreptomycinChemoprophylaxis of Pneumonic plaque : TetracyclinePre term labour : NifedipineHIV associated lipodystrophy : TesamorelinProphylaxis of bleeding varices : PropanololDysentry due to Shigella : CiprofloxacinChlamydia infection in pregnancy : AzithromycinSpecific myoclonic syndrome : Valporic acidCyanide poisoining : Hydroxycobalamine
HUS is due to
Shigella
Salmonella
E. Coli
None
E. Coli
Viral markers in Hepatitis
Acute diagnosis : HBsAg , IgM anti-HBcChronic diagnosis : IgG anti-HBc, HBsAgMarkers of replication : HBeAg , HBV DNA
Lateral geniculate body
6 Layers ▪ Layers 1,4,6 : Receive input from CONTRALATERAL hemicornea▪ Layers 2,3,5 : Receive input from IPSILATERAL hemicornea.
Pathways •Magnocellular (Large) Pathway: ▪ Layers 1, 2 ▪ Movements, depth, flickering
•Parvocellular pathway: ▪ Layers 3 to 6 ▪ Fine details, shape, colour, texture etc.
Q) Most afferent fibres from the LG nucleus terminate in 1° visual cortex is : Layer 4.
Oral Ca
M/c site : Lower lipM/c site of Oral ca in Nepal & India : Alveolobuccal sulcusM/c site of tongue : Mid 1/3rd lateral margin or Distal 2/3rd.M/c HPE : SCCM/c route of spread in Oral cancer : LymphaticsDistant Metastasis is rarer,If developed m/c site is "Lung." Premalignant condition: M/c : LeucoplakiaMost Premalignant condition : ErythroplakiaChronic Hyperplastic Candidiasis. IOC : Wedge biopsy (from edge of ulcer)Radiological IOC : MRIFor Alveolar involvement, Radiological IOC : NCCT > OPG.
Most common cause of
•Unilateral proptosis in children : Orbital cellulitis•Non inflammatory cause of unilateral proptosis in children : Dermoid cyst•Bilateral proptosis in children : Metastatic neuroblastoma ; and or leukaemia (chloroma)•Unilateral / bilateral proptosis in adults : Thyroid ophthalmopathy•Benign orbital tumors in adults : Cavernous hemangioma•Malignant orbital tumor in adults : lymphoma•Intraocular malignant tumour in children : Retinoblastoma•1°Intraorbital malignant tumour in children : Rhabdomyosarcoma•Intraorbital tumour in children : Capillary Hemangioma•Benign orbital tumor in children : Dermoid cyst or Capillary Hemangioma (??)•1°Intraoccular malignant tumour in adults : Uveal Melanoma•Intraocular malignant tumour in adult : Metastasis•Source of Orbital Metastasis in adults : Breast•Source of Orbital Metastasis in children : Neuroblastoma•Epithelial tumour of Lacrimal gland : Pleomorphic Adenoma•Eyelid tumour : BCC
Prader willi syndrome Vs Angelman syndrome
Prader willi syndrome Paternal deletion / Maternal additions Paternal inheritence Maternal imprinting
Angelman syndrome
TIPSS
•Shunt is placed between Right hepatic vein and Right portal vein.
Oral Ca
M/c site : Lower lipM/c site of Oral ca in Nepal & India : Alveolobuccal sulcusM/c site of tongue : Mid 1/3rd lateral margin or Distal 2/3rd.M/c HPE : SCCM/c route of spread in Oral cancer : LymphaticsDistant Metastasis is rarer,If developed m/c site is "Lung." Premalignant condition: M/c : LeucoplakiaMost Premalignant condition : ErythroplakiaChronic Hyperplastic Candidiasis. IOC : Wedge biopsy (from edge of ulcer)Radiological IOC : MRIFor Alveolar involvement, Radiological IOC : NCCT > OPG.
Most common
• Mediastinal mass in adults (overall) : Neurogenic tumours (23%) > Thymomas (2nd)• Mediastinal mass in children : Neurogenic tumours (Thymoma are rare)• Most frequent location of mediastinal mass : Anterosuperior mediastinum• Neurogenic tumours in adults : Neurofibromas and Neurilemomas• Neurogenic tumours in children : Gangliomas and Neuroblastomas. • Most malignant masses of mediastinum : Lymphomas• Most common mediastinal germ cell tumours : Teratomas.
Incidence rate is calculated by
Cohort study
Osteochondritis of
Central bony nucleus of vertebral body : Calve's diseaseMetatarsal head : Frieberg's diseaseCalcaneal tuberosity : Sever's disease
All of the following enzymes may contribute to generation of free oxygen radicals within neutrophils for killing intracellular bacteria except
A) Superoxide dismutase
B) NADPH oxidase
C) Fenton's reaction
D) Glutathione peroxidase
D) Glutathione peroxidase
Test for syphilis
Most sensitive test for 1° syphilis : TP-PA1st test to become positive : FTA-ABSTest of choice for rapid serological diagnosis : RPRTest for monitoring the response of therapy : RPR or VDRLTesting large no. of sera for screening or diagnostic purpose : RPR or VDRLTest for confirmation : FTA-ABS or TPPA or TPHATest for Congenital syphilis : 195 IgM FTA-ABSThe diagnostic test : TP-PATest of choice for diagnosis of Neurosyphilis : VDRL of CSF
Metabolic disturbance in
Ureterosigmoidoscopy : Hyperchloremic hypokalemic metabolic acidosisTPN : Hyperchloremic hyperkalemic metabolic acidosisLarge Villous adenoma : Hypokalemic metabolic acidosisPost burn patient : Hyperkalemic metabolic acidosis
Most common joint involved in
Syphilitic arthritis : KneeGonococcal arthritis : KneeRA : MCPReactive arthritis : KneePsoriatic arthritis : DIP>PIPSenile osteoporosis : VertebraPagets disease : Pelvic bone>femur>skullActinomycosis : mandibleAcute Osteomyelitis : Lower end of femurBrodie abscess : Upper end of tibiaCharcot's arthropathy : Mid tarsal
Edge of Septic ulcer is
Sloping
Absolute C/I of OCPs are all except
A. Breast Ca
B. Hepatoma
C. Sickle cell disease
D. Thromboembolism
C. Sickle cell disease
Neoplastic vs Non neoplastic polyps
Non neoplastic polyps : ▪Hyperplastic polyp ▪Juvenile polyp ▪Peutz-Jeghers polyp ▪Mucus retention polyp
Neoplastic polyps : ▪Adenomatous polyp ▪Tubular adenomas ▪Villous adenomas ▪Familial polyposis coli ▪Gardner's syndrome ▪Turcot's syndrome
Pseudopolyps are not premalignant.
Hepatitis B virus
Acute diagnosis : HBsAg, IgM anti-HBcChronic diagnosis : IgG anti-HBc, HBsAgMarkers of replication : HBeAg, HBV DNA
Not transmitted through sexual route
A. Hepatitis A
B. Hepatitis E
C. Both Hepatitis A and E
D. Hepatitis D
B. Hepatitis E
As a sexually transmitted disease, Hepatitis A may occur mainly among homosexual men due to oroanal contact.
Labourer's nerve is
Median nerve
Ulnar nerve is a/k/a "Musician's nerve".
Flail chest is defined as
3 or more fracture in 2 or more consecutive ribs
Sleep apnea is defined as a temporary pause in breathing during sleep lasting at least
10 seconds
Five or more episodes of obstructive apnea or hypopnea per hour of sleep documented during a sleep study.
α-helix and β-pleated sheets are example of which protein structure
A. Secondary structure
B. Quaternary structure
C. Tertiary structure
D. Primary structure
A. Secondary structure
Marker for hepatitis B virus replication
A. HbsAg
B. HBs - IgM
C. HBcAg
D. HBeAg
D. HBeAg
Herpes simplex Encephalitis involves
A. Frontal lobe
B. Occipital lobe
C. Temporal lobe
D. Parietal lobe
C. Temporal lobe
WHO recommended dose of Zinc in Acute diarrhoea
•< 6 months : 10 mg daily•> 6 months : 20 mg daily
Recommended treatment for 10 to 14 days.
Sumitriptan is a
5-HT1D/1B agonist
Lorcaserin : 5HT2C agonist (Anti-obesity drugs)
Tegaserod : 5HT4 partial agonist Newer drug Acts as an partial agonist in the colon. Approved for the use of chronic constipation but because of CVS toxicity, its use is now restricted.
Conditions that resemble Atropic rhinitis is
A. Rhinoscleroma
B. Vasomotor rhinitis
C. None
D. Rhinosporidiosis
A. Rhinoscleroma
Strawberry gall bladder is seen in
A. Wegener's granulomatosis
B. Mirizzi syndrome
C. Cholesterosis
D. Porcelain gall bladder
C. Cholesterosis
Which of the following is associated with development of Chalcosis
Iron
Copper
Lead
Mercury
Copper
Different time events during fertilization
LH surge : 24 hr before ovulationOvulation : 0 hrsFertilization : 24 hrs after ovulation (Day 1)Reaches uterine cavity : 3-4 days post fertilization (Day 4-5 post ovulation)Implantation : 7-9 day post fertilization
Systemic inflammatory response syndrome
2 or more of the following criteria are met for SIRS ▪Temperature ≥38°C (100.4°F) or ≤36°C (96.8°F) ▪HR ≥90 beats/min ▪RR ≥20 breaths/min or PaCO2 ≤32 mm of Hg or mechanical ventillation. ▪WBC ≥12000/microL or ≤4000/microL or ≥10% band forms.
Paranasal sinuses and their openings
1) Anterior ethmoidal air cells : Drain through tiny openings in the hiatus semilunaris of the middle meatus. 2) Middle ethmoidal air cells : Drain through the ethmoidal bulla of the middle meatus. 3) Posterior ethmoidal air cells : Drain through openings in the superior meatus. 4) Frontal sinuses : Drains into the anterior part of the hiatus semilunaris. 5) Maxillary sinuses : Opens into the posterior aspect of the hiatus semilunaris in the middle meatus. 6) Sphenoidal sinuses : Drains into the space above the superior concha called the sphenoethmoidal recess.
Shoulder dystocia is managed by
A. 90° rotation of posterior shoulder
B. Sharp flexion of hip joints towards abdomen
C. Suprapubic pressure
D. Emergency CS
C. Suprapubic pressure
Most common uterine anomaly is
Septate uterus > Bicornuate uterus
Type of error
Type l error : Null hypothesis is true but rejected.Type ll error : Null hypothesis is false but not rejected ( or accepted )
Some points
★Specificity of a screening test is the ability of a test to detect : True negatives★Sensitivity of a screening test is the ability of a test to detect : True positives★Usefulness of screening test is given by : Sensitivity★Statistical index of Diagnostic accuracy : Sensitivity★Diagnostic power of a screening test : Predictive accuracy★Diagnostic power of screening test to correctly identify a disease : Positive predictive value★Diagnostic power of screening test to correctly exclude a disease : Negative predictive value
Most common hematological malignancies in children
A. ALL
B. CML
C. CLL
D. AML
A. ALL
An anaesthesia resident was giving spinal anaesthesia when the patient had certain aphonia and loss of consciousness. What could have happened
A. Intravascular injection
B. Total spinal
C. Vasovagal shock
D. Partial spinal
C. Vasovagal shock
Incubation period
1-6 hrs : Staphylococcus aureus, Bacillus cereus12-48 hrs : Salmonella, E. Coli48-72 hrs : Shigella, Campylobacter>7 days : Giardiasis, Amoebiasis
M/C organisms causing CAP is
S. Pneumoniae
All of the following have higher risks of malignancy except
A. Juvenile polyps
B. Juvenile polyposis
C. FAP
D. Peutz Jeghers syndrome
A. Juvenile polyps
Colour of stools in breastfeed newborn is
A. Green
B. Black
C. Golden
D. Red
C. Golden
Meconium is the first stool passed within 24 hours. After that meconium stools (black tarry) can be passed up to 3 days. On 4th - 5th days transitional stools (Greenish) are passed. After 5 days regular milk stools (Golden yellow) are passed.
Staphyloma involves
Iris with cornea
Most common cause of anterior staphyloma is Sloughing corneal ulcer. Most common cause of posterior staphyloma is degenerative high axial myopia.
Albinism is due to
Tyrosinase deficiency
Creeping fat is characteristic of
A. CD
B. Lymphocytic enterocolitis
C. Collagenous colitis
D. UC
A. CD
Openings in lateral wall of nose
★ Sphenoethmoidal recess : Opening of the sphenoidal air sinus
★ Superior meatus : Opening of the posterior ethmoidal air sinus
★ Middle meatus : ◇ On bulla : Opening of the middle ethmoidal air sinus◇ In hiatus semilunaris : ▪ Anterior part : Opening of frontal air sinus▪ Middle part : Opening of anterior ethmoidal air sinuses▪ Posterior part : Opening of the maxillary air sinuses
★ Inferior meatus : NLD in anterior part of meatus.
Gall stones seen in Sickle cell anemia is
Calcium bilirubinate
Craniosacral outflow is mediated by
Sympathetic postganglionic fibres
Sympathetic preganglionic fibres
Parasympathetic postganglionic fibres
Parasympathetic preganglionic fibres
Parasympathetic preganglionic fibres
Smoking is most commonly associated with
A. Small cell Lung Ca
B. Adenocarcinoma
C. Squamous cell carcinoma
D. Carcinoid Tumour
C. Squamous cell carcinoma
Le fort fracture
Le fort l : Floating palate (horizontal)Le fort ll : Floating maxilla (Pyramidal)Le fort lll : Floating face (transverse)
Most common
Tumor of Salivary gland : Pleomorphic adenomaBenign tumor of salivary gland : Pleomorphic adenomaMalignant tumor of major salivary gland : Mucoepidermoid tumor Malignant tumor of minor salivary gland : Adenoid cystic carcinomaBenign and overall tumor of parotid in children especially in <1 yr : HemanglomaMalignant tumor in children : MucoepidermoidRadiation induced neoplasm of salivary gland : Mucoepidermoid carcinoma
Supports of uterus are all except
A. Broad ligament
B. Levator ani
C. Transverse cervical ligament
D. Sacro-cervical ligament
A. Broad ligament
Post exposure prophylaxis is given in all except
A. Measles
B. Rabies
C. Pertusis
D. Hepatitis B
C. Pertusis
Others : Rabies Measles (within 3 days of exposure) Tetanus Hepatitis B Varicella
Wernicke's encephalopathy is characterised by all except
A. Polyneuritis
B. Opthalmoplegia
C. Peripheral neuritis
D. Ataxia
C. Peripheral neuritis
Peripheral neuritis is a manifestation of dry beriberi.
Cranial irradiation is also indicated in the treatment of which variety of lung cancer
A. Small cell cancer
B. Squamous cell carcinoma
C. Adenocarcinoma
D. Non small cell cancer
A. Small cell cancer
Cubitus valgus deformity is a complication of
A. Fracture of lateral epicondyle of humerous
B. Fracture of head of radius
C. Fracture of lateral condyle of humerous
D. Fracture of olecranon
A. Fracture of lateral epicondyle of humerous
Best indicator of fertility
A. Age specific fertility rate
B. TFR
C. NRR
D. GFR
C. NRR
Lithium produce
A. Hyperparathyroidism
B. Hypothyroidism
C. Hyperparathyroidism
D. Hypoparathyroidism
B. Hypothyroidism
Splenomegaly for which Splenectomy is effective
A. Aplastic anemia
B. Sickle cell disease
C. ITP
D. Thalassemia
C. ITP
Antimalarial of choice in a pregnant woman in the first trimester who is chloroquine resistant is
A. Mefloquine
B. Proguanil
C. Dapsone and Pyrimethamine
D. Quinine
A. Mefloquine
Chloroquine is the DOC for malaria in pregnancy.
Drugs used in prophylaxis of preeclampsia is
A. Valporate
B. Prochlorperazine
C. Heparin
D. Aspirin
D. Aspirin
Vaccine associated paralytic poliomyelitis is suspected if AFP develops within how many days of receipt of OPV
A. 45
B. 30
C. 60
D. 90
B. 30
Mechanism of action of methotrexate
Inhibit dihydrofolate reductase
The cell junctions allowing exchange of cytoplasmic molecules between two cells are called
A. Anhhoring junction
B. Tight junctions
C. Focal junction
D. Gap junctions
D. Gap junctions
Blindness as per WHO defination is
A. VA of <20/400 (6/120) in the better eye with best possible correction
B. VA of <20/60 (6/18) in the better eye with best possible correction
C. VA of <20/60 (6/18) in the worst eye with best possible correction
D. VA of <20/400 (6/120) in the worst eye with best possible correction
A. VA of <20/400 (6/120) in the better eye with best possible correction
Hypothermia grading
Mild : 35°C (95°F) to 32.2°C (90°F)Moderate : <32.2°C (90°F) to 28°C (82.4°F)Severe : <28°C (<82.4°F)
Infant mortality rate doesnot include
A. Perinatal mortality
B. Post natal mortality
C. Early neonatal mortality
D. Late neonatal mortality
A. Perinatal mortality
Type of amputation and length of the stump
Above knee : 12 cm (4.8 inches)Below knee : 14 inches (5.6 inches)Below elbow : 18 cm (7.2 inches)Above elbow : 20 cm (8 inches)
Commonest malignancy of ovary
A. Granulosa cell tumour
B. Mucinous
C. Serous
D. Dermoid cyst
C. Serous
Hypoxia causes deoxygenation of Hb by
Increasing band 3 tyrosine phosphorylation. This stimulate releasing of all glycolytic enzymes of band 3 on RBC membrane thereby stimulating glycolysis.
Uterine souffle is
A. Indicates the underlying fetal distress
B. Is due to increase in blood flow through the dilated uterine vessels
C. Is a soft blowing murmur synchronous with fetal heart sound
D. Is due to the active fetal movement
B. Is due to increase in blood flow through the dilated uterine vessels
Funic souffle : •It is a sharp whistling sound that is synchronous with fetal pulse. •It is caused by the rush of blood through the umbilical arteries and may not be heard consistently.
Haversian system is seen in
A. Articular cartilage
B. Cortical bone
C. None
D. Cancellous bone
B. Cortical bone
Familial dyslipidemias
Type l : Hyperchylomicronemia▪ AR ▪ LPL or Apo C ll deficiency ▪↑blood level : CM, TG, Cholesterol
Type ll : Familial cholesterolemia▪ AD ▪ Absent or defective LDL receptors ▪↑blood level : lla : LDL, Cholesterol , llb : LDL, Cholesterol, VLDL
Type lll : Dysbetalipoproteinemia▪ AR ▪ Defective Apo E ▪↑blood level : CM, VLDL
Type IV : Hypertriglyceridemia▪ AD ▪ Hepatic overproduction of VLDL ▪↑blood level : VLDL, TG
Four muscles compress the vagina and acts as a sphincter
Pubovaginalis External urethral sphincter Urethrovaginal sphincter Bulbospongiosus
Gold standard / Best investigation for Tubal patency
A. Laproscopic chemotubation
B. HSG
C. Laprotomy
D. Rubin's test
A. Laproscopic chemotubation
Most common site of gastric malignancy
Ca stomach : Proximal stomachCa stomach in Pernicious anaemia : FundusDiffuse variety : FundusGastric lymphoma : AntrumBurkitt's lymphoma / EBV : Cardia / Body
Most common cause of Community aquired bacterial meningitis
A. GBS
B. N. Meningitis
C. S. Pneumoniae
D. L. Monocytogens
C. S. Pneumoniae (50%)
Approximate duration between LH surge and ovulation
A. 12-18 hrs
B. 34-36 hrs
C. 48-50 hrs
D. 18-20 hrs
B. 34-36 hrs
LH secretion peaks at 10-12 hrs before ovulation.
Signature fracture of skull is seen in
A. Suture separation
B. Depressed fracture
C. Ring fracture
D. Gutter fracture
B. Depressed fracture
Billings method is
A. Basal body temperature method
B. Symptothermal method
C. Basal body temperature and calander method
D. Cervical mucous method
D. Cervical mucous method
Rhythm method : Calander method
Spermatic pathway
[@ STEEVE]
Seminiferous tubules rete Testis vasa Efferentia Epididymis Vas deferens Ejaculatory duct
Menopausal hot flashes is due to
A. LH surge
B. Decreased progesterone
C. Decreased estrogen
D. FSH surge
C. Decreased estrogen
Km vs Vmax
In competitive inhibition : Km value increases but Vmax remain constant.
In non competitive inhibition : Vmax decreases but Km remains constant.
One of the following drug penetrates into caseous necrosis in tuberculosis
A. Pyrizinamide
B. Ethambutol
C. Rifampicin
D. Isoniazid
C. Rifampicin
After renal transplantation of patient develop fever and symptoms of encephalopathy. Histology shows post transplant lymphoma. It occurs due to proliferation of
A. NK cells
B. T cells
C. Monocyte
D. B cells
D. B cells