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Side chains of amino acids

  1. Thiol + pKa
    • pKa: 8.40
    • Amino acid: Cysteine (C)

    (Side chain contains SH)
  2. Carboxylate + pKa
    • pKa: 4.00
    • Amino acids: Aspartate (D) & Glutamate (E)

    (Side chains contain COO-)
  3. Imidazole + pKa
    • pKa: 6.00
    • Amino acid: Histidine (H)

    (See slide #9)
  4. Amino + pKa
    • pKa: 10.5
    • Amino acid: Lysine (K)

    (Side chain contains NH3+)
  5. Guanidinium + pKa
    • pKa: 12.5
    • Amino acid: Arginine (R)

    (See slide #9)
  6. Hydroxyl + pKa
    • pKa: 13.0
    • Amino acids: Serine (S) & Threonine (T)

    (Side chains contain OH)
  7. Phenol + pKa
    • pKa: 10.5
    • Amino acid: Tyrosine (Y)

    (Contains an OH attached to a benzene)
  8. pKa of alpha-amino group in a free amino acid
    pKa: 9.40
  9. pKa of alpha-carboxyl group in a free amino acid
    pKa: 2.20
  10. pKa of amino group in a peptide
    pKa: 8.00
  11. pKa of carboxylate group in a peptide
    pKa: 3.00
  12. Side chain for Alanine
    Methyl
  13. Side chain for Phenylalanine
    Phenyl
  14. Side chain for Glycine
    H
  15. Side chain for Isoleucine
    Sec-butyl
  16. Side chain for Leucine
    Isobutyl
  17. Side chain for Methionine
    Thioether
  18. Side chain for Asparagine & Glutamine
    Carboxamide
  19. Side chain for Proline
    Pyrrolidine
  20. Side chain for Valine
    Isopropyl
  21. Side chain for Tryptophan
    Indole
Author
sophathida
ID
350327
Card Set
Side chains of amino acids
Description
Pka, amino acids
Updated

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