Name the area of the nervous system where chemical signals are passed from one neuron to the next
Synaptic cleft
What part of the neuron recurved the chemical signal
Dendrite
What is resting membrane potential?
-70mV
What causes resting membrane potential
Na+/K+ ATPase
K+ Leak Channels
What does the Na+/K+ filter do
Pumps out 3 Na+
Brings in 2 K+
Hydrolyzes 1 ATP to do this
What does a K+ leak channel do
Stays open & allows K+ owt
What is an axn potential
Disturbance in membrane potential
Depolarization of plasma membrane
What is threshold potential?
-50mV
What happens at threshold potential?
Channels open fully
When do channels close?
When membrane potential reaches +35mV
How does repolarization happen ?
Voltage gated Na+ channels deactivate
Voltage gated K+ channels open
What is the membrane potential at hyperpolarization ?
-90mV
What is saltatory conduction ?
Rapid jumping of conduction in myelinated axons
Name the cells that create myelin in the PNS
Schwann Cells
Name the cells that create myelin in the CNS
Oligodendrocytes
What is equilibrium potential?
Membrane potential at which there is no net movement of ions
What is the difference between absolute refractory period and relative refractory period ?
In absolute refractory period there is no depolarization no matter how hard the signal
In relative refractory if there is a strong enough signal there will be depolarization
Where will you see an electrical signal
Seen in cytoplasm of 2 cells connected by gap junction
In smooth and cardiac muscle
Where does a chemical signal occur?
At the end of axons
Where is the neuromuscular jxn?
Between neurons and skeletal muscle
What is the enzyme that degrades acetylcholine left over in the synaptic cleft ?
Acetylcholinesterase
What is temporal summation ?
When axn potential is fired so rapidly that excitatory postsynaptic potentials (EPSP) or inhibitory postsynaptic potentials (IPSP) pile on top of ea. Other
What is spatial summation ?
When IPSP & EPSP are taken at a given point in time