Mix of 6-10 estrogenic substances; can be synthetic or from natural sources (plant, yam, soybean, equine)
Estradiol route of administration?
Oral tablets
Transdermal patch
Vaginal ring
Vaginal cream, tablet
Long acting depot injections
Which type of hormone therapy should be avoided?
Compounded bioidentical hormones
What is the black box warning for estrogen hormone replacement?
There is increased risk of endometrial cancer in a woman with a uterus who used unopposed estrogen for a prolonged period of time
What is the black box warning regarding estrogen dosage?
Estrogens with or without progestin should be described at the lowest effective doses and the short duration consistent with treatment goals and risks of the individual woman
What is Evamist? What is the black box warning for it?
Transdermal estrogen
Black box warning for unintentional
Who is at increased risk for developing endometrial cancer?
Postemenopausal women on estrogen therapy with an intact uterus
What should postmenopausal women with intact uterus do if they are on estrogen therapy?
Adequate concomitant progesterone
What are examples of oral progestins you can use in addition to estrogen?
Medroxyprogesteron acetate
Micronized progesterone
What is treatment form GU syndrome of menopause/ Vulvovaginal atrophy?
Low-dose vagina estrogen therapy is recommended over systemic estrogen therapy
T/F: progesterone is recommended with low-dose vaginal estrogen therapy
False; progesterone therapy is not recommended in treatment of vulvo-vaginal atrophy/ GU syndrome
Bazedoxifene can reduce the risk of __________
Endometrial hyperplasia that may be caused by conjugated estrogens component
What is the product name of a conjugated estrogen + bazedoxifene combination?
Duavee
Dyspareunia can be treated with his estrogen receptor agonist/antagonist
Ospemifene
Has agonistic effects on the endometrium
What are nonhormonal management of menopause associated vasomotor symptoms?
