Radiographic Adrenal Gland Clinical Anatomy

  1. Superior adrenal artery is a branch of the _______ artery
    Inferior phrenic
  2. Inferior phrenic artery arises from the _______
    Aorta
  3. T/F: superior adrenal artery arises from the aorta
    False; The inferior phrenic artery arises from the aorta and that branches into the superior adrenal artery.
  4. What structure arises between the inferior mesenteric artery and the bifurcation of the aorta?
    islands of Zukerandl
  5. What imaging modality is associated with incidentaloma findings?
    CT scan
  6. T/F: pheochromocytomas is a tumor of the adrenal gland, and it usually secretes cortisol and aldosterone
    False; it usually secretes norepinephrine
  7. What is necessary for the physician to do before obtaining a biopsy of the adrenal mass?
    Determined whether the mass is functional or not
  8. What is the effect of exogenous steroids on adrenal function?
    Exogenous steroids like prednisone suppress normal adrenal function
  9. T/F: a MRI without contrast is the best imaging modality used to locate accessory loci of an active pheochromocytoma
    False; it is MIBG scan
  10. What is MIBG scan?
    The best imaging modality to locate accessory loci of an active pheochromocytoma
  11. What is the most common cause of adrenal calcifications?
    Hemorrhage
  12. T/F: pheochromocytoma is the most common cause of adrenal calcifications
    False; it is hemorrhage
  13. _____ and _____ carcinomas can invade the IVC
    • Renal
    • Adrenal
  14. The most common metastatic tumor to the adrenal gland is ______
    Lung cancer
  15. T/F: Lung cancer can invade the IVC
    False; renal and adrenal carcinomas can invade the IVC. Lung cancer is the most common metastatic tumor that affect the adrenal gland.
  16. T/F: if a surgeon accidentally ligates the superior and middle adrenal arteries in kidney removal surgery, he should remove the affected adrenal gland and immediately administer steroid bolus
    False; he should just do nothing because the affected adrenal gland still has ample blood supply
  17. Accidentally ligated the superior and middle adrenal arteries, what should you do?
    Nothing! There are plenty of blood supply for that adrenal gland, so no worries
  18. Patient with a 1.2 cm left adrenal mass detected, what is the next step?
    Request serum and urine testing to assess the functionality of the mass
  19. Which one of the adrenal glands is right next to the IVC?
    Right adrenal gland
  20. T/F: adrenal cancer can spread to other retroperitoneal organs
    True, it is a retroperitoneal organ, just like kidney, “C” loop of duodenum, pancreas and large vessels
  21. Three branches of arterial inflow to adrenal gland:
    • Superior suprarenal artery (aka superior adrenal artery)
    • Middle suprarenal a
    • Inferior suprarenal a
  22. Superior suprarenal a is a branch of the _____ artery. Middle suprarenal comes directly off the _____ and inferior suprarenal artery comes off ______.
    • Inferior phrenic (branch off the aorta)
    • Aorta
    • Renal
  23. Most anterior to most posterior of structures in the renal hilum:
    • Most anterior: renal vein
    • Renal artery
    • Ureter
  24. Adrenal Incidentaloma is an adrenal mass of generally _____ cm or more
    • 1
    • This is usually discovered incidentally on CT
  25. T/F: incidentalomas are usually benign
    True
  26. T/F: when an incidentaloma is detected on CT, do a biopsy to evaluate whether it is benign or malignant
    • False!; do not do this!!! Don’t biopsy adrenal mass until you can be sure whether the mass is metabolically active or not.
    • Pheochromocytoma can set off an epinephrine storm
  27. If you biopsy a pheochromocytoma, ______ can occur
    Epinephrine storm
  28. Diagnostic modalities used in evaluating an adrenal mass with difficult lesions, such as vascular involvement:
    • CT and MRI to evaluate, especially pheochromocytomas and paragangliomas
    • (ultrasound is not routinely used)
  29. Left adrenal gland is usually ____ shape on cross-section, and Righ adrenal gland is _____ shape
    • Y shape
    • Banana
  30. What structure on cross section that could be mistaken with adrenal glands?
    crus of the diaphragm
  31. Anterior to posterior: pancreatic tail, crus of diaphragm, adrenal gland, splenic vein
    • Pancreatic tail
    • Splenic vein
    • Adrenal gland
    • Crus of diaphragm
  32. T/F: spleen, like adrenal gland and pancreas, is retroperitoneal organ
    False; it is intraperitoneal. Adrenal gland and pancreas are retroperitoneal
  33. T/F: calcified adrenal cysts are usually benign
    True
  34. Cushing’s ______ means there is pituitary adenoma
    Disease
  35. Cushing’s ____ means there is elevated cortisol
    Syndrome
  36. T/F: Aldosterone is increased in Cushing’s syndrome
    False; cortisol is increased
  37. What is the most common cause of Cushing’s?
    • Pituitary adenoma- Cushing’s disease
    • (second most common is adrenal adenoma- cushing syndrome)
  38. Adrenal hemorrhage is the most common cause of ______, and these could be manifested in/under these conditions:
    • Most common cause of adrenal calcifications
    • Seen in: sepsis, dehydration, anticoagulant, trauma, ketoconazole use, surgical stress, pregnancy, etc
  39. Bilateral adrenal hemorrhage causing ______ hematomas
    Perinephric
  40. Hemorrhage in the adrenals can cause loss of adrenal hormones, this condition is known as ______
    Addison’s disease
  41. What is adrenal myelolipoma?
    • A benign tumor that is perfectly round
    • Do MRI to confirm that it is benign
  42. What is the organ of Zuckerkandl?
    • Para-aortic bodies.
    • Small chemoreceptors masses of chromaffin cells near the sympathetic ganglia along the abdominal aorta from IMA to the bifurcation
  43. What is pheochromocytoma?
    • Neuroendocrine tumor forming in the chromaffin cells of adrenal medulla or extra-adrenal tissues
    • Secretes Norepinephrine or epinephrine analogues
  44. Epinephrine stimulates ______ receptors
    Beta (so pheochromocytoma will have presentations relating to stimulation of beta-receptors, ie palpitations, hypertension)
  45. 10% of adrenal tumors are ______, and 10% of that are _______, _____, _____, ______, and ______
    • Pheochromocytoma
    • Bilateral, malignant, extra-adrenal, calcified and Familial
    • This is the rule of 10’s. (in case it wasn’t obvious)
  46. How is pheochromocytoma diagnosis usually confirmed?
    • Usually on blood work/ urine (this also determines whether it is secreting NorE or Epi)
    • NEVER stick a needle in there for biopsy!
  47. Areas between the inferior mesenteric artery and the bifurcation of the aorta, _______ can be found.
    Organ of zuckerkandl
  48. T/F: increased epinephrine secretion from pheochromocytoma suggests malignant tumor
    False; increased dopamine suggests malignant tumor. Tumor usually secretes increased epinephrine and norepinephrine
  49. T/F: about 40% of patients with both Cushing syndrome and adrenal mass also have a malignant tumor
    True
  50. Which type of adrenal tumors are usually malignant in men
    Feminizing
  51. Incidences of primary adrenal cancer (2 major peaks in life):
    • First decade of life
    • Again in the fourth to fifth decades
  52. Adrenal masses greater than ______ cm needs to be removed; vs typical adrenal carcinoma:
    • 6 cm
    • Typical adrenal carcinoma are large (>4 cm) unilateral mass with irregular edges
  53. What are the four most common sites of cancer metastasis? (in order)
    • Lung
    • Liver
    • Bone
    • Adrenals
  54. Adrenal metastases are found in 50% of cases of ________
    • Malignant melanoma
    • (lung cancer is most common adrenal metastasis)
  55. T/F: Adrenal gland growing into the IVC can spread to right atrium of the heart
    True
  56. Which imaging modality is used for detection and localization of benign and malignant intra-adrenal and extra-adrenal pheochromocytomas?
    MIBG (using guanethidine analog that is absorbed similarly as norepinephrine into chromaffin cells)
  57. T/F: MIBG allows for detection of increased metabolically-active tissue
    • False; this is the definition for PET scan
    • MIBG is used for pheochromocytoma detection
Author
lykthrnn
ID
349027
Card Set
Radiographic Adrenal Gland Clinical Anatomy
Description
Endo Exam 2
Updated