Normal and Abnormal Growth Clinical

Midparental height, aka _____ height. For boys, add ____inches or ____ cm to ___’s height. Plus _____’s height and divided by 2.

This imagining modality can evaluate a child’s bone age:

Short stature is ____ SD from the average height

Growth curve for a child that falls under the category of familial short stature:

Growth curve for a child that falls under the constitutional delay short stature category:

Pathologic short statures is ______ SD below the mean for chronologic age

Growth rate for pathologic short statures is ______ below the mean for chronologic age

Pathologic short stature is when height is _____ below the target height when corrected for midparental height

Pathologic short stature is defined as:

T/F: Chronic diseases like renal dz, asthma, CF, cardiac, celiac, AIDS and cancer can cause abnormal short stature growth pattern
True False

GH deficiency, cortisol excess, hypothyroidism are examples of ______ cause of _____ growth pattern for short stature

Turner syndrome, noonan syndrome and achondroplasia are abnormal growth pattern for ____ stature

Short stature genetic causes:

Short stature endocrine causes:

15 year old girl whose height falls 3 SD below the average, comes in with lack of breast development (so what, neither did i), spaced nipples, webbed neck, shortened 4th metatarsals and left-sided heart disease, likely ______

A short patient comes in with facial dysmorphism and downward slanted eyes and low-set ears, likely _______. What are some other features that he may display?

A very short person comes in with a prominent forehead, short arms and thighs, what is the genetic mutation that occurred in this person?

Growth hormone therapy can be used for these conditions:

T/f: doses for adults on growth hormone therapy is higher than for children
True False

What are adverse effects of growth hormone therapy?

Tall stature is defined as condition in which the height of an individual is ____ above the corresponding mean height for a normal subject of the same age and sex

Bone age = _____

Tall stature from normal constitutional growth display _____ bone age

Final height of “early bloomers” is ______

When there is growth hormone excess causing abnormal tall stature, think _____

Gigantism is excess of which hormone?

Excess GH before fusion of epiphyseal growth plates is ____

McCune Albright Syndrome (MAS), Multiple endocrine neoplasia type 1 (MEN 1), Carney complex are ______ excess, resulting in ___ stature

Excess GH after epiphyseal plates closed is ____

T/F: Acromegaly is excess GH resulting in linear bone growth
True False

T/F: GH excess that begins in adulthood, after complete epiphyseal fusion, has no effect on stature
True False

Non-GH excess cause of tall stature:

Penile enlargement with pubic hair but prepubertal testes seen in a boy is _____

Stature at time of diagnosis of Congenital Adrenal Hyperplasia is _____, and final height is ____

Abdominal CT of congenital adrenal hyperplasia shows ______

Bone age of a 9 year old boy with congenital adrenal hyperplasia would be ______

Elevated urinary 17-ketosteroid levels, elevated serum 17-hydroxyprogesteron is indicative ____

Precocious puberty is onset of secondary sexual development before age _____ in girls, and ___ in boys

Precocious puberty stature at the time of diagnosis is ____, and final height stature is ____

T/F: Congenital adrenal hyperplasia and precocious puberty both are tall stature at time of diagnosis and short final height; so these two are in both short and tall stature schemes
True False

Genetic causes of abnormal tall stature:

Marfan and Klinefelter leads to ____ Stature

Very tall prepubertal boys with small testes, gynecomastia, marked lack of insight, poor judgement and impaired ability is likely _____, and this is due to chromosomal abnormality____.

Chronic diseases can cause _____ stature

Highest rate of growth in boys is ages ______, and In girls is ______

T/F: growth charts provides information is growth over time and it also gives info about the rate of growth
True False

How is the growth velocity curve computed?

Use the CDC growth chart for age _______, and use the WHO growth chart for age _____.

Children over three years height should be measured while _____

For ages 2-3 years, children’s height measurement depends on_____

T/F: children under 2 years of age, height is measured with parents holding them up on their feet
True False

Three phases of post natal growth are:

Total growth in the infantile post natal growth phase is ______, and this happen in the _____ years of life

A rapid but decelerating growth describe which phase of the post natal growth phase?

Childhood phase growth is ______ velocity of _____ cm per year

A “pre-pubertal dip” describes which phase of the post natal growth phase?

Pubertal phase consists of growth spurts of ______ cm per year

Infants should be measured ____ clothes to the nearest _____ kg or _____ oz