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Pyoderma Gangrenosum (PG)
- Rare, chronic inflammatory disease with unknown etiology with painful skin ulcers
- Legs most commonly effected
- Surgery & Sharp debride are avoided as it can trigger PG
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Kaposi Sarcoma
- Cancer that develops from cells that line lymph or blood vessels
- Caused by HIV
- Most often in males
- Presents as red to purple asymptomatic spots, become painful
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Sickle Cell Ulcerations
- chronic leg ulcers
- usually black or hispanic descent
- may develop after trauma or spontaneous
- Not completely understood
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Calciphylaxis
- excessive calcium deposited in microvascular system causing painful necrotic lesions
- Seen exclusively in end stage renal dx and hyperparathyroidism
- Calcium & phos must be brought to low/norm levels safely
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Pemphigus
- rare autoimmune skin disorder characterized by epidermal blistering of skin
- Effects all races, prevalent in middle age & older
- skin lesions, recurrent blisters, flaccid mouth ulcers
- Nikolsky's sign positive (skin is loosened and when rubbed, slips free just as skin on blanched tomato)
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Kennedy terminal ulcer
ulcer many people get as they are passing away
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fungating malignant wounds
malignant wounds caused by infiltration of epidermis by primary or metastic tumor
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Marjolin Ulcer
- squamous cell carinoma arising at sites of chronic inflammation or wounds
- usually long period btwn injury and malignant transformation - may be 10 -25 years
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silver sulfadiazine
- broadspectrum antivacterial creme, aka Silvadene
- impedes fibroblast activity
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type of specialty absorptive dressing
hydrofiber dressing
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What is contraindicated for use with silver products
Enzymatic debrider (Santyl)
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Half life of pre-albumin
1-2 days
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at risk level for pre-albumin
<16 mg
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What is half life of albumin
18-21 days
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What may impede fibroblast function
silver sulfadiazine
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