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define chronic wound
- a wound that has failed to proceed orderly through the healing process
- Ex: dm wound, venus ulcer, pressure ulcer
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define acute wound
a disruption in the integrity of the skin and underlying tissues that progress through the healing cascade in a timely and uncomplicated manner
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Define Recalcitrant wounds
- "recalcitrant" wound is one which fails to respond to interventions.
- After multiple interventions, the wound fails to progress
- stubborn, resistant
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What two things do you need to heal a wound
healthy pt and healthy wound bed
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New term for non-compliance
non-adherence
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Sebum
- is a lipid-rich oily substance produced by sebaceous glands in skin
- when mixed with sweat, makes the acid mantle which gives skin it's pH
- helps protect skin
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epidermis & layers
- external skin surface
- 5 layers:
- Stratum corneum
- stratum lucidum
- stratum granulosum
- stratum spimosum
- stratum germinativum
- "Corny Luck Granted, Spi Jerm's (Germ)"
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stratum corneum
- also called horny layer
- is superficial layer of dead skin cells, is shed daily
- like bark of tree
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stratum lucidum
- also called clear layer
- only present in thick skin
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stratum granulosum
- granular layer
- multilayer (1-5 cells thick)
- cells become compressed, aids in keratin formation
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Stratum spinosum
Spiny layer
Several layers thick - cells of this layer begin to produce keratin
- cells begin to flatten
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Stratum germinativum
- granular layer - only one cell thick
- only layer in which cells undergo mitosis to form new cells
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Cells of Epidermis
- Keratinocytes
- Desmosomes
- Melanocytes
- Langerhans cells
- "Kinky Destany Melted Lucifer"
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Keratinocytes
- manufacture keratin which is a protein responsible for the toughness of the epidermis
- takes them 4-6 weeks to migrate from stratum germinativum to corneum
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Desmosomes
specialized structures which bind adjacent keratinocytes to one another and give cohesion to each layer during it's upward progression
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Melanocytes
- cells which produce melanin, the brown pigment of skin
- purpose is to protect your skin by absorbing harmful UV rays
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Langerhans Cells
- Cells which are active in the capture, uptake and processing of antigens (substances that stimulates immune response
- first line of defense against enviro antigens
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basement membrane
- forms junction between dermis and epidermis
- As we age, it flattens out and is subject to shearing forces that tend to separate the layers
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function of epidermis
- barrier against toxic substances/microorganisms
- prevents water loss
- repels water
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dermis and what is contains
- supports & nourishes epidermis
- contains nerves, sweat glands, sebaceous glands, and hair follicles
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ECM (Extracellular matrix)
- largest component of dermis
- gel-like matrix made up of sugars and proteins
- functions as structural support for cells, regulates cellular function, lubricates and provides transport system for nutrients and waste products
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cells of dermis & where produced
- macrophages
- mast cells
- fibroblast
- nerves
- langerhans cells
*produced in bone marrow
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macrophages
scavenger cells that ingest dead tissues, repair injured tissue, and act as defense
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mast cells
- contain heparin and histamine
- provides defense such as blood clotting after injury or infection
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fibroblast
- cells from which connective tissue is developed
- also produce collagen and elastin
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collagen
protien which gives skin tensile strength
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elastin
protein which provides skin with elastic recoil
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functions of dermis
- nourish
- protect against mechanical injury and microorganisms
- sense environment
- thermoregulation
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subcutaneous tissue
- loose connective tissue which binds skin loosely to subjacent tissues
- contains lyphatics and deep vessel blood supply
- channels nutrients and O2 to dermis
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fascia
- white shinny sheaths covering for muscle, nerves and blood vessles
- give support to muscle fibers, keeping tight bundles
- non-viable fascia is grayish in color
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ligaments
connects two or more bones together
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tendons
attaches muscle to bone
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when assessing surrounding tissue or periwound, how far out needs to be observed
min of 4 cm
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sagging edges
- generally occurs with wounds that have undermining
- is due to lack of SQ support around wound & combined with gravity, edges droop and sag
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eschar
- dry, desiccated (no moisture) necrotic tissue
- firm dry, leathery
- if moistened, slowly turns to slough
- is remnant of collagen matrix
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slough
- hydrated necrotic tissue
- color varies including: yellow, gray, tan, brown
- is soft and thin, fibrinous, stringy or mucinous
- is remnant of collagen matrix
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epithelial tissue
- outermost layer of skin is composed of epithelial cells. as wounds heal, they regenerate across wound
- deep pink to pearly pink
- light purple from edges in full thickness wounds
- may form islands in superficial
- can have islands or bridging
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granulation tissue
- also known as connective tissue or scar tissue
- beefy deep red irregular surface
- replaces the dead tissue
- *if its regular and smooth, not granulation
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serous exudate
- thin clear watery plasma (seen in partial thick wounds/venous ulcers)
- moderate to heavy amount may indicate heavy bio-burden to sub-clinical infection
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sanguinous
bloody (fresh bleeding)
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serosanguineous
thin, watery, pale red to pink, plasma with rbc's
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seropurulent
- thin, watery, cloudy, yellow to tan
- could mean infection
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purulent
- thick, opaque, tan yellow, green or brown
- never normal
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epibole
- rolled/curled under edges
- migrates down sides of wound instead of across
- body thinks wound is closed
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sinus tract
a discharging blind-ended track that extends from surface of skin to underlying area or abcess cavity
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brawny edema
- hardened, fibrotic, non pitting edema
- maybe dusky in color
- indicated lymphodema
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induration
- process of skin "becoming hard"
- *red flag for undermining, tunneling, sinus tract of infection
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fluctuance
- movable compressible,
- palpable fluid filled cavity
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callus
excessive thickening of skin caused by chronic shearing
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maceration
white wrinkles from excessive moisture
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ecchymosis
non-blanchable discoloration of variable size may be caused by vascular wall damage, trauma, or vasculitis
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vesicle
- circular, free fluid filled
- up to 1cm
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bulla
- circular, free fluid filled,
- greater than 1cm
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macule
- change in color of skin
- ,circular, flat discoloration
- less than 1 cm
- ex: freckle
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patch
same as macule, except larger than 1cm
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papule
- superficial, solid elevated mass
- less than 1 cm
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nodule
- circular, elevated, solid mass greater than 1 cm
- may be seen in epidermis, dermis, or subcutaneous tissue
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pustule
- circular, collection of leukocytes
- free fluid filled
- varies in size
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wheal
- firm, edematous plaque, infiltration of dermis
- may last a few hours
- ex: hives, tb test
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plaque
- superficial, elevated, solid, flat topped lesion
- greater than 1 cm
- ex: psoriasis
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fissure
crack or split in skin
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lichenification
- refers to thickening of epidermis
- usually due to chronic rubbing or scratching of area
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excoriation
- linear erosion
- destruction of skin my mechanical means
- ex: scratching
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denuded
loss of epidermis, caused by exposure to urine, feces, body fluids, exudate or friction
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2 questions to always ask
- 1. is there viable tissue present?
- No - 100% necrotic, unstageable
- Yes - see #2
- 2. what viable tissue is present?
- *muscle, tendon, bone... stage 4
- *dermis, SQ.... unstageable because necrotic could areas could be deeper than dermis
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how long until a DTI is seen
- 7 day rule
- once seen, it probably occurred 7 days ago
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mucosal pressure ulcers
pressure ulcers found on mucous membranes caused by medical device
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nociceptive pain
- acute pain
- localized, constant, noncyclic or cyclic
- limited and will stop
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neuropathic pain
- results from damaged or malfunctioning nerve fibers
- described as "burning" or "electric shock" feeling
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