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Pulmonary Pharmacology Lecture 2
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Who does asthma typically affect?
Women
Kids
African Americans
Living in the N. East
Below poverty level
Work Exposure (asbestos, fine particulates)
How is asthma characterized?
Activation of mast cells, infiltrates of eosinophils, T helper 2
Asthma is considered a "reversible" disease, whereas COPD is considered to be a ____ disease.
"non-reversible"
Name common triggers of asthma
Pollen
Smoke
Mold
Pollution
Exercise
Perfumes
Pet Dander and dust mites
When is the onset of asthma typically?
Early in life
COPD is characterized physiologically by ___.
the predominance of neutrophils, macrophages, and cytotoxic T 1 cells
How does COPD affect the lungs?
inflammation affects small airways resulting in progressive small airway narrowing and fibrosis
Changes in the airways in people with COPD results in ___.
airway closure on
expiration
leading to
air trapping
and
hyperinflation
What are common causes of COPD?
Smoking
Environmental factors
When is the onset of COPD?
mid-life
What do COPD and asthma have in common?
chronic inflammation of the airways
What can help keep patients out of acute exacerbations?
Routine maintenance medications
COPD patients often have ____ PaO2 and ____PaCO2 levels.
lower; higher
What is the preferred route of medication delivery for COPD and asthma patients?
Oral route
β2 receptors cause ____ of smooth muscle in the lungs.
relaxation
Which system affects the lung airways in a slow action mechanism, sympathetic or parasympathetic system?
parasympathetic system
What are β2 Adrenergic Agonists used for?
Bronchodilator for COPD or Asthma
Name
s
hort
a
cting
b
eta
a
gonists
What are the 3 subcategories of bronchodilators used to treat Asthma?
Beta agonists
Muscarinic antagonists
Methylxanthines
What are the 3 main drug categories used to treat Asthma?
Bronchodilators
Anti-inflammatory agents
Leukotriene antagonists
What are the 4 anti-inflammatory agents used to treat asthma?
Release inhibitors
Steroids
Antibodies
Allow anti-inflammatory drugs
What are the 2 categories of leukotrienes antagonists to treat asthma?
Lipoxygenase inhibitors
Receptor inhibitor
What are the main drug categories used to treat COPD?
Bronchodilators
Anti-inflammatory agents (steroids)
Antibiotics
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Author
cheerios258
ID
347274
Card Set
Pulmonary Pharmacology Lecture 2
Description
Pulmonary pharmacology and treatment
Updated
2019-05-31T01:20:34Z
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