Salivary Secretions Physiology

  1. Initial starch digestion is by _____, initial triglyceride digestion is by ____
    • Salivary alpha amylase
    • Lingual lipase
  2. What is pH in the mouth?
  3. Where is saliva secreted from?
    Cells lining the acinus
  4. True/false: saliva electrolyte concentration is similar to plasma
    True; K+ and HCO3- secreted into the lumen by salivary ductal cell, while Na+ and Cl- reabsorbed to interstitium
  5. At slow flow rate of saliva, the concertation of saliva is ____to plasma and at high rates, saliva is more ___ plasma. This is in fact, the opposite of pancreatic juice flow
    • Different
    • Same as
  6. True/false: production of saliva is increased by sympathetic nervous system activity but not parasympathetic nervous system activity.
    False; it is by BOTH parasympathetic and sympathetic nervous systems
  7. Which of the nervous system have more effect on saliva production?
    Parasympathetic over sympathetic
  8. Do hormones have an affect on saliva production? Which ones?
    Trick question, hormones do NOT affect saliva production
  9. Which nerves are innervated in saliva production?
    Parasympathetic signaling through facial and glossopharyngeal nerves
  10. Receptor on which cells assist in control of saliva production? Through which cellular signaling pathway?
    • Muscarinic Ach receptors on acinar and ductal cells
    • IP3 and increased intracellular Ca2+
  11. Salivary production is reduced by which factors?
    • Sleep
    • Dehydration
    • Fear
    • Anticholinergic drugs
  12. Where does sympathetic input come from?
    Superior cervical ganglion with preganglionic input from T1 to T3
  13. Sympathetic signaling release which neurotransmitter and affect which receptor?
    NE, Beta adrenergic receptors on acinar and ductal cells
  14. What is the cellular signaling pathway via sympathetic transmission?
    Increases saliva secretion through cAMP
Card Set
Salivary Secretions Physiology
GI Midterm- Physiology