Acute phase proteins

• - CRP
• - procalcitonin
• - ferritin
• - fibrinogen
• - alpha-1 antitrypsin
• - caeruloplasmin
• - serum amyloid A
• - haptoglobin
• - complement

During acute phase response, liver DECREASES production of other proteins: 


Examples include:

• - albumin
• - transthyretin (formerly known as - prealbumin)
• - transferrin
• - retinol binding protein
• - cortisol binding protein

• - a protein synthesised in the liver
• - binds to phosphocholine in bacterial cells and on those cells undergoing apoptosis
• - then activate complement system

• - Known to rise 
• - >150 at 48h post op -> evolving complications