When does sepsis arise?
body's response to an infection injuries its own tissues and organs
what can sepsis lead to?
- multiple organ failure
what is sepsis?
a life threatening organ dysfunction due to a dysregulated host response to infection
what is suspected sepsis?
used to indicate people who might have sepsis and require face to face assessment and consideration of urgent intervention
what is sepsis most likely to develop from?
what are some common sources of sepsis?
- infected wound
- device related infection e.g. catheter, IV
- infection can be suspected but source not obvious
how many people die from sepsis every year?
how much are long term complications from sepsis due to delayed diagnosis costing the UK economy every year?
how much more likely are you to die from sepsis than ACS or stroke?
6 times more likely
who is at risk of sepsis?
- >75 years
- weak immune system
- recent surgery
- recently had a serious illness
what women are at risk of sepsis?
- just given birth or recently been pregnant
- inc miscarriage or abortion
what aged babies are at risk of sepsis?
- younger than 1 year
- born prematurely
- mothers has an infection while she was pregnancy
what are pt receiving chemotherapy?
what is step one in recognising sepsis?
- Does the pt look unwell?
- calculate NEWS score
what is step 2 of recognising sepsis?
confirm suspicion or evidence of infection
what are the signs and/or symptoms of infection you would be looking out for for step 2 of recognising sepsis?
- Upper respiratory tract infection (URTI)/ LRTI
- abdominal pain and Diarrhoea & Vomiting
- soft tissue infection/ infected wound
- device related infection
- hidden source e.g. pressure sores
what neurological symptoms may there be?
- new confusion
what respiratory/ cardiovascular may there be?
- cough +/- sputum
- chest pain, palpitations
- raised respiratory rate or effort. SOB (SOBOE)
what gastrointestinal may there be?
- nausea/ vomiting, altering bowel habits
- abdominal pain
- abdominal distension/ localized tenderness
what genito-urinary may there be?
- discharge/ STD
- UTI- loin pain on urination, urgency, frequency, back, back pain
what musculo- skeletal may there be?
hot painful joint +/- non weight bearing
what are other signs and symptoms?
- dental problems and/or sinus infection
- foreign travel
- exposure to sick contacts
- cellulitis and wounds
- diabetic foot and ulcers
- purpuric rash
- weight loss
- reduced appetite
what is step 3 of recognistion of sepsis?
if any one of the following flags are present, red flags sepsis is present
what are the red flags for sepsis?
- RR ≥25 per min
- HR >130
- SBP <90 mmHg or mean arterial pressure <65 mmHg
- oxygen needed to keep spo2 ≥ 92%
- NEWS ≥ 5
- response to voice pain or is unresponsive
- mottled, ashen or cyanotic
- long term steroids
- anuria in the 18 hours
- recent chemotherapy