Haemophilus influenzae Microbiology

  1. What is gram stain and shape of Haemophilus influenzae?
    • Gram negative
    • Coccobacilli
  2. True/False: H. influenzae has a human reservoir and it is part of the normal microbiota
    True, kinda…. Nontypeable strain is part of normal microbiota. Typeable strain is not part of normal microbiota
  3. Is typeable strain of H. influenzae part of the normal microbiota?
    No
  4. Is nontypeable strain of H. influenza part of the normal microbiota?
    Yes
  5. What are the two strains of H. influenzae?
    • Typeable
    • Nontypeable
  6. True/False: nontypeable strain of H. influenzae has a capsule
    False
  7. True/False: typeable strain of H. influenzae has a capsule
    True
  8. Is nontypeable strain of H. influenzae part of the normal microbiota and does it have a capsule?
    Part of microbiota, unencapsulated
  9. Is typeable strain of H. influenzae part of the normal microbiota and does it have a capsule?
    Not part of microbiota, capsulated
  10. Is type B H. influenzae (Hib) capsulated or unencapsulated?
    Capsulated
  11. Is type B H. influenzae (Hib) part of the normal microbiota?
    No
  12. What is H. influenzae oxygen need?
    Facultative anaerobe
  13. For nontypeable strains of H. influenzae, where are they normally found in the human body?
    Upper respiratory tract
  14. What can nontypeable strains cause?
    • Mucosal infections: otitis media, sinusitis, bronchopneumonia
    • What can typeable strains cause?
    • Meningitis
    • Epiglottitis
    • Septic arthritis
    • Cellulitis
    • Osteomyelitis
  15. Which strain of H. influenzae can cause more serious infections?
    Typeable strain. They have capsules
  16. What type of agar do H. influenzae grow on?
    Chocolate
  17. What does a chocolate agar contain?
    Growth factors: X factor and V factor
  18. What is the major virulence factor for typeable H. influenzae?
    PRP (polyribitol phosphate) capsules
  19. What are some virulence factor of nontypeable H. influenzae?
    • LOS (in all gram negatives)
    • IgA1 protease
  20. How is H. influenzae transmitted?
    • Endogenous from URT
    • Person-to-person
  21. Is Quellung reaction positive in Hib?
    Yes
  22. What does Quellung reaction positive look like?
    • Capsular precipitation and swelling
    • Capsule more apparent
  23. Can Hib be prevented with vaccine?
    Yes
  24. How can H. influenzae be treated?
    • Life threatening: ceftriaxone
    • Non life threatening: amoxicillin-clavulanate
Author
lykthrnn
ID
345637
Card Set
Haemophilus influenzae Microbiology
Description
Pulmonary Final- Microbiology
Updated