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Haemophilus influenzae Microbiology
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What is gram stain and shape of Haemophilus influenzae?
Gram negative
Coccobacilli
True/False: H. influenzae has a human reservoir and it is part of the normal microbiota
True
False
True, kinda…. Nontypeable strain is part of normal microbiota. Typeable strain is not part of normal microbiota
Is typeable strain of H. influenzae part of the normal microbiota?
No
Is nontypeable strain of H. influenza part of the normal microbiota?
Yes
What are the two strains of H. influenzae?
Typeable
Nontypeable
True/False: nontypeable strain of H. influenzae has a capsule
True
False
False
True/False: typeable strain of H. influenzae has a capsule
True
False
True
Is nontypeable strain of H. influenzae part of the normal microbiota and does it have a capsule?
Part of microbiota, unencapsulated
Is typeable strain of H. influenzae part of the normal microbiota and does it have a capsule?
Not part of microbiota, capsulated
Is type B H. influenzae (Hib) capsulated or unencapsulated?
Capsulated
Is type B H. influenzae (Hib) part of the normal microbiota?
No
What is H. influenzae oxygen need?
Facultative anaerobe
For nontypeable strains of H. influenzae, where are they normally found in the human body?
Upper respiratory tract
What can nontypeable strains cause?
Mucosal infections
: otitis media, sinusitis, bronchopneumonia
What can typeable strains cause?
Meningitis
Epiglottitis
Septic arthritis
Cellulitis
Osteomyelitis
Which strain of H. influenzae can cause more serious infections?
Typeable strain. They have capsules
What type of agar do H. influenzae grow on?
Chocolate
What does a chocolate agar contain?
Growth factors: X factor and V factor
What is the major virulence factor for typeable H. influenzae?
PRP (polyribitol phosphate) capsules
What are some virulence factor of nontypeable H. influenzae?
LOS (in all gram negatives)
IgA1 protease
How is H. influenzae transmitted?
Endogenous from URT
Person-to-person
Is Quellung reaction positive in Hib?
Yes
What does Quellung reaction positive look like?
Capsular precipitation and swelling
Capsule more apparent
Can Hib be prevented with vaccine?
Yes
How can H. influenzae be treated?
Life threatening
: ceftriaxone
Non life threatening
: amoxicillin-clavulanate
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Author
lykthrnn
ID
345637
Card Set
Haemophilus influenzae Microbiology
Description
Pulmonary Final- Microbiology
Updated
2019-02-27T19:01:22Z
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