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What is the gram stain and shape of Legionella pneumonphila?
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True/False: legionella is biolfim former
True
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True/false: legionella grows on special agar called BCYE
True
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Legionella stains (well/poorly), usually done with ____ stain.
Poorly; silver
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True/False: Legionella is usually found in air conditioners, water-cooling towers, shower heads, taps, hot tubs, misters
True
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Can Legionella be found in human reservoir and part of our normal microbiota?
No and no
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Can Legionella lead to typical community acquired pneumonia?
No, they are atypical causes of community acquired pneumonia
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True/false: legionella can lead to community-acquired pneumonia and healthcare-associated pneumonia
True
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What is Legionella’s oxygen need?
Aerobes
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True/False: Legionella is facultative intracellular in PMNs
False; facultative intracellular macrophages
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Which symptoms are more predominant with Legionella infections, GI or respiratory?
GI symptoms more predominant than respiratory symptoms
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True/False: Legionella likes warm water
True
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True/False: Legionella don’t stain well, usually seen in micrograph as brown to black against a yellow background
True
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Legionella is _____(fastidious/non-fastidious), and ____(require/not require) special agar.
Fastidious; require
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What is the agar use for Legionella?
Buffered charcoal yeast extract agar (BCYE)
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What are virulence factors for Legionella?
- Facultative intracellular
- Biofilm formers
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How is Legionella transmitted?
Aerosols, aspiration
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True/false: legionella person-to-person transmission is common
False; person to person spread is rare with Legionella
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Legionellosis pneumonia often affects _____ (immune healthy/ immunocompromised) patients.
Immunocompromised
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How is Legionella diagnosed?
Urine antigen test and BCYE culture
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How to treat Legionella?
Levolfloxacin (fluoroquinolone)
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