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Bacillus anthracis Microbiology
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What is the gram stain and shape of bacillus anthracis?
Gram positive
Rods
True/False: B. anthracis is endospore former
True
False
True
True/False: B. anthracis has a capsule
True
False
True
How would pulmonary B. anthracis infection show on Xray?
Widened mediastinum
Pleural effusions
Do B. anthracis have capsule?
Yes
Are B. anthracis endospore formers?
Yes
What would show on CSF analysis for B. anthracis?
Gram positive bacteria
Lots of neutrophils
True/False: lymphocytosis is often a result for B. anthracis infection
True
False
False; there is elevated PMNs not lymphocytes. Lymphocytosis is with B. pertussis
True/False: B. anthracis has a human reservoir
True
False
False; they live in soil/ vegetation, hence the endospore formers
True/False: B. anthracis is used as a bioweapon
True
False
True
What is B. anthracis oxygen need?
Aerobe to facultative anaerobe
True/False: B. anthracis requires special nutrient agar
True
False
False; they are non-fastidious, nutrient or blood agar suffice
What are virulence factors of B. anthracis?
Endospore former
Capsule
Replication in macrophage
AB exotoxin complex
How do B. anthracis get around macrophages?
Antiphagocytic capsule
Replicate within macrophage
Inhibit proliferation of macrophage with lethal factor
How is capsule a virulence factor?
Avoid getting phagocytosed
True/False: B. anthracis can replicate within a macrophage in the case that it is engulfed by one
True
False
True
What is lethal factor
Inhibits proliferation various cell types including macrophages
What composes the AB exotoxin complex of B. anthracis?
Protective antigen, edema factor enzyme, lethal factor enzyme
True/False: transmission of anthrax is often through occupational exposure
True
False
True
What are prominent symptoms of pulmonary anthrax?
Hemorrhagic mediastinitis
Pleural effusions
True/false: B. anthracis pulmonary infection is usually benign and non-fatal
True
False
False; 90-100% if not treated immediately
How many forms of anthrax infections are there? What are they?
3
Cutaneous
Respiratory
GI
What is the typical lesion seen in cutaneous anthrax?
Black eschar
Local edema
How could anthrax be prevented?
Animal vaccines
Biosafety level 3 labs
What is the treatment for inhalation anthrax?
Antibiotics and monoclonal antibody
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Author
lykthrnn
ID
345635
Card Set
Bacillus anthracis Microbiology
Description
Pulmonary Final- Microbiology
Updated
2019-02-27T18:29:40Z
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