Bordetella pertussis Microbiology

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Shape and Gram stain of Brodetella pertussis:
- Gram negative
- Coccobacilli
Which growth media do Bordetella pertussis grow on?
- Bordet-Gengou
- Regan-Lowe
See Bordet Gengou agar and Regan Lowe agar, think which bacteria:

Bordetella pertussis
Is Bordetella pertussis vaccine preventable?

Yes
True/False: Bordetella pertussis has a human reservoir and is part of the normal microbiota

False; it does have a human reservoir but is definitely NOT normal microbiota
Bordetella pertussis is aerobic or aerobic?

Aerobic
Major virulence factor for B. pertussis:
- Adhesins
- Exotoxins
Does B. pertussis have adhesins?

Yes
B. pertussis produces exotoxin or endotoxin?

Exotoxins
What are exotoxins produced by B. pertussis?
- Tracheal cytotoxin
- Pertussis toxin
What is tracheal cytotoxin?

Exotoxin produced by B. pertussis targeting and destroying ciliated tracheal epithelial cells
What is pertussis toxin?

A major virulence factor for B. pertussis, an AB exotoxin that results in lymphocytosis
True/False: B. pertussis results in neutrophilia

False; it results in lymphocytosis, which is uncommon for bacterial infections
How is B. pertussis transmitted?

Respiratory droplets
What is the toxin that destroys cilia?

Tracheal cytotoxin
True/False: B. pertussis directly invade cells and spread deeper

False; pertussis toxin disseminates, bacteria do not invade cells directly
What does B. pertussis cause?
- Whooping cough
- Pneumonia most common complication
How is B pertussis diagnosed?
- Culture + PCR recommended
- Marked lymphocytosis
- Nasopharyngeal swab
True/False: Culturing B. pertussis should occur early on (<4 weeks) in the infection

True
How is whooping cough treated?

Macrolide

Author

lykthrnn

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Card Set

Bordetella pertussis Microbiology

Description

Pulmonary Final- Microbiology

Updated

2019-02-27T18:03:52Z