Regulation of Coronary Blood Flow & Myocardial Oxygen

  1. Blood flow through coronary vasculature is greatest during _________________
    Diastole
  2. Why is coronary blood flow greatest during diastole? (3)
    • Partial occlusion of coronary artery from aortic valve cusps
    • Compression of intramyocardial coronary vessels during systole (dilation during diastole)
    • Reactive hyperemia
  3. What is reactive hyperemia?
    Increasing blood flow following a period of occlusion
  4. True or false. The heart cannot really increase the amount of oxygen extracted from arterial blood.
    True
  5. What does the heart do to match an increased myocardial oxygen demand?
    Increases coronary blood flow
  6. What are the factors that affect myocardial oxygen supply?
    • Patency of coronary vessels
    • Ventricular wall compression
    • Diastolic filling time
  7. What are the factors that affect myocardial oxygen demand?
    • Heart rate
    • Myocardial contractility
    • Afterload
  8. What are the significant contributors to afterload?
    Ventricular pressure and thickness of wall
  9. How does ANS modulate coronary blood flow?
    • Alters coronary vascular resistance (directly)
    • Alters heart rate and therefore metabolic activity (indirectly)
  10. Coronary blood flow is modified primarily by ________________
    Myocardial metabolic activity
  11. Compare and contrast the volume work of the left and right ventricles
    Same for both
  12. Compare and contrast the pressure work of the left and right ventricles
    Pressure work is higher in left (aorta)
Author
stepha998
ID
344654
Card Set
Regulation of Coronary Blood Flow & Myocardial Oxygen
Description
ATSU
Updated