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Regulation of Coronary Blood Flow & Myocardial Oxygen
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Blood flow through coronary vasculature is greatest during _________________
Diastole
Why is coronary blood flow greatest during diastole? (3)
Partial occlusion of coronary artery from aortic valve cusps
Compression of intramyocardial coronary vessels during systole (dilation during diastole)
Reactive hyperemia
What is reactive hyperemia?
Increasing blood flow following a period of occlusion
True or false. The heart cannot really increase the amount of oxygen extracted from arterial blood.
True
False
True
What does the heart do to match an increased myocardial oxygen demand?
Increases coronary blood flow
What are the factors that affect myocardial oxygen supply?
Patency of coronary vessels
Ventricular wall compression
Diastolic filling time
What are the factors that affect myocardial oxygen demand?
Heart rate
Myocardial contractility
Afterload
What are the significant contributors to afterload?
Ventricular pressure and thickness of wall
How does ANS modulate coronary blood flow?
Alters coronary vascular resistance (directly)
Alters heart rate and therefore metabolic activity (indirectly)
Coronary blood flow is modified primarily by ________________
Myocardial metabolic activity
Compare and contrast the volume work of the left and right ventricles
Same for both
Compare and contrast the pressure work of the left and right ventricles
Pressure work is higher in left (aorta)
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Author
stepha998
ID
344654
Card Set
Regulation of Coronary Blood Flow & Myocardial Oxygen
Description
ATSU
Updated
2019-01-15T07:29:30Z
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