-
-
Evista
- Raloxifene
- med guide required (also for tamoxifen)
-
-
-
-
Ibrance
- Palbociclib
- used with letrozole or fulvestrant, improves outcomes
-
-
-
Supprelin
Vantas
Histrelin
-
-
Firmagon
- Degarelix
- Given SQ once monthly
-
-
Niladron
- Nilutamide
- disulfiram rxns
-
-
-
-
-
Gliadel
BiCNU
- Carmustine
- use nonPVC bag and tubing
-
-
-
Bendeka
Treanda
Bendamustine
-
Myleran
Busulfex
Busulfan
-
Gleostine
- Lomustine
- fatal toxicity with overdosage
- no more than one dose at a time every 6wk
-
Mustargen
Valchor topical gel
Mechlorethamine
-
Alkeran
Evomela
Melphalan
-
-
-
-
Valstar
- Valrubicin
- only used as bladder instillation but can have systemic toxicity
-
Doxil
Lipodox50
- Doxorubicin liposomal
- not interchangeable with nonliposomal adriamycin
-
Vincasar PFS
- Vincristine
- not myelosuppressive
- capped at 2mg/dose regardless of mg/m2 calc
-
Navelbine
- Vinorelbine
- myelosuppressive
-
Marqibo
- Vincristine liposomal
- not interchangeable with vincristine
-
Jevtana
- Cabazitaxel
- premed with h2ra, steroid and benadryl
-
Abraxane
- Paclitaxel albumin bound
- no premeds required
- hypersensitivity rxns not due to taxanes, but due to solvent, which is why they need premeds
- all taxanes need nonPVC bag except this one
-
Hycamtin
- Topotecan
- only use when ANC>1500cells/mm3 and plts>100k cells/mm3
- topo1 inhibitors
-
-
Etopophos
- Etoposide phosphate
- helpful in pts with fluid restriction
-
VePesid
- Etoposide caps
- refrigerate capsules
- IV:PO ratio is 1:2
- doses >200mg need to be given in divided doses due to reduced bioavailability
-
Efudex
Carac
Tolak
Fluoroplex
- 5FU
- topical formulations used for actinic keratosis
- Vistogard (uridine triacetate) can be given as antidote for overdose due to DPD deficiency
-
Efudex
- 5FU
- used also for basel cell carcinoma
-
ara-C
Cytarabine conventional
-
DepoCyt
Cytarabine liposomal for intrathecal admin
-
-
Alimta
- Pemetrexed
- give folic acid, vitb12, dexamethasone
-
-
Trisenox
- Arsenic trioxide
- second line of therapy for APL
- 1st line of therapy for APL is tretinoin
-
Erwinaze
- Asparaginase
- derived from erwinia chrysanthemi
-
Oncaspar
- Pegaspargase
- derived from EColi
-
Afinitor
- Everolimus
- Zortress is for transplant
- medguide required
-
Torisel
- Temsirolimus injection
- premed with diphenydramine
- use nonPVC bag and tubing
-
Revlimid
- Lenalidomide
- REMS program
- medguide required
- consider ppx anticoag d/t increased VTE risk
-
Pomalyst
- Pomalidomide
- REMS
- medguide required
- consider ppx anticoag due to increased VTE risk
-
Velcade
- Bortezomib
- SC admin has less neuropathy than IV admin
-
-
Cyramza
- Ramucircumab
- use 0.22 micron filter
-
-
Kadcyla
- Ado-trastuzumab
- use 0.22 micron filter
- not interchangeable with herceptin
-
Vectibix
- Panitumumab
- use 0.22 micron filter, same with erbitux
-
Arzerra
- Ofatumumab
- med guide required
-
Gazyva
- Obinutuzumab
- med guide required
-
Adcetris
- Brentuximab vedotin
- CD30 antigen must be positive for use
-
Blincyto
- Blinatumomab
- CD19 and CD3 must be positive for use
- medguide required
-
Darzalex
- Daratumuab
- CD30 must be positive for use
-
Keytruda
- Pembrolizumab
- medguide required
-
Opdivo
- Nivolumab
- medguide required
-
Tecentriq
- Atezolizumab
- medguide required
-
Yervoy
- Ipilumumab
- REMS
- medguide required
-
-
Tasigna
- Nilotinib
- medguide required
-
Iclusig
- Ponatinib
- medguide required
-
-
-
-
-
-
Gilotrif
- Afatinib
- dose adj for renal impairment
-
-
-
Xalkori
- Crizotinib
- ocular toxicity
-
-
Alecensa
- Alectinib
- myalgia and photosensitivity
-
Tykerb
- Lapatinib
- must have HER2 overexpression to use
-
-
-
take with food or within 1hr after meal
- Gleevec
- Thalomid
- Xeloda
- Aromasin
-
Take on empty stomach (1h before or 2h after)
- Tasigna
- Tarceva
- Nexavar
- Tremodar
- Zytiga
- Pomalyst (2h before or 2h after food)
-
Take without regard to food
- Sprycel
- Sutent
- Nolvadex
- Arimidex
- Casodex
- Relimid
- Femara
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