Oncology 2

  1. Faslodex
    Fulvestrant
  2. Evista
    • Raloxifene
    • med guide required (also for tamoxifen)
  3. Fareston
    Toremifene
  4. Femara
    Letrozole
  5. Aromasin
    Exemestane
  6. Ibrance
    • Palbociclib
    • used with letrozole or fulvestrant, improves outcomes
  7. Eligard
    Leuprolide
  8. Zoladex
    Goserelin
  9. Supprelin
    Vantas
    Histrelin
  10. Trelstar
    Triptorelin
  11. Firmagon
    • Degarelix
    • Given SQ once monthly
  12. Casodex
    Bicalutamide
  13. Niladron
    • Nilutamide
    • disulfiram rxns
  14. Xtandi
    Enzalutamide
  15. Zytiga
    Abiraterone
  16. Cytoxan
    Cyclophosphamide
  17. Iflex
    Ifosfamide
  18. Gliadel
    BiCNU
    • Carmustine
    • use nonPVC bag and tubing
  19. Matulane
    Procarbazine
  20. Hexalen
    Altretamnie
  21. Bendeka
    Treanda
    Bendamustine
  22. Myleran
    Busulfex
    Busulfan
  23. Gleostine
    • Lomustine
    • fatal toxicity with overdosage
    • no more than one dose at a time every 6wk
  24. Mustargen
    Valchor topical gel
    Mechlorethamine
  25. Alkeran
    Evomela
    Melphalan
  26. Temodar
    Temozolomide
  27. Ellence
    Epirubicin
  28. Idamycin
    Idarubicin
  29. Valstar
    • Valrubicin
    • only used as bladder instillation but can have systemic toxicity
  30. Doxil
    Lipodox50
    • Doxorubicin liposomal
    • not interchangeable with nonliposomal adriamycin
  31. Vincasar PFS
    • Vincristine
    • not myelosuppressive 
    • capped at 2mg/dose regardless of mg/m2 calc
  32. Navelbine
    • Vinorelbine
    • myelosuppressive
  33. Marqibo
    • Vincristine liposomal
    • not interchangeable with vincristine
  34. Jevtana
    • Cabazitaxel
    • premed with h2ra, steroid and benadryl
  35. Abraxane
    • Paclitaxel albumin bound
    • no premeds required 
    • hypersensitivity rxns not due to taxanes, but due to solvent, which is why they need premeds
    • all taxanes need nonPVC bag except this one
  36. Hycamtin
    • Topotecan
    • only use when ANC>1500cells/mm3 and plts>100k cells/mm3
    • topo1 inhibitors
  37. Toposar
    Etoposide IV
  38. Etopophos
    • Etoposide phosphate
    • helpful in pts with fluid restriction
  39. VePesid
    • Etoposide caps
    • refrigerate capsules
    • IV:PO ratio is 1:2
    • doses >200mg need to be given in divided doses due to reduced bioavailability
  40. Efudex
    Carac
    Tolak
    Fluoroplex
    • 5FU
    • topical formulations used for actinic keratosis
    • Vistogard (uridine triacetate) can be given as antidote for overdose due to DPD deficiency
  41. Efudex
    • 5FU
    • used also for basel cell carcinoma
  42. ara-C
    Cytarabine conventional
  43. DepoCyt
    Cytarabine liposomal for intrathecal admin
  44. Gemzar
    Gemcitabine
  45. Alimta
    • Pemetrexed
    • give folic acid, vitb12, dexamethasone
  46. Folotyn
    Pralatrexate
  47. Trisenox
    • Arsenic trioxide
    • second line of therapy for APL
    • 1st line of therapy for APL is tretinoin
  48. Erwinaze
    • Asparaginase
    • derived from erwinia chrysanthemi
  49. Oncaspar
    • Pegaspargase
    • derived from EColi
  50. Afinitor
    • Everolimus
    • Zortress is for transplant 
    • medguide required
  51. Torisel
    • Temsirolimus injection
    • premed with diphenydramine
    • use nonPVC bag and tubing
  52. Revlimid
    • Lenalidomide 
    • REMS program
    • medguide required
    • consider ppx anticoag d/t increased VTE risk
  53. Pomalyst
    • Pomalidomide
    • REMS
    • medguide required
    • consider ppx anticoag due to increased VTE risk
  54. Velcade
    • Bortezomib
    • SC admin has less neuropathy than IV admin
  55. Kyprolis
    Carfilzomib
  56. Cyramza
    • Ramucircumab
    • use 0.22 micron filter
  57. Perjeta
    Pertuzumab
  58. Kadcyla
    • Ado-trastuzumab
    • use 0.22 micron filter 
    • not interchangeable with herceptin
  59. Vectibix
    • Panitumumab
    • use 0.22 micron filter, same with erbitux
  60. Arzerra
    • Ofatumumab
    • med guide required
  61. Gazyva
    • Obinutuzumab
    • med guide required
  62. Adcetris
    • Brentuximab vedotin
    • CD30 antigen must be positive for use
  63. Blincyto
    • Blinatumomab
    • CD19 and CD3 must be positive for use
    • medguide required
  64. Darzalex
    • Daratumuab
    • CD30 must be positive for use
  65. Keytruda
    • Pembrolizumab
    • medguide required
  66. Opdivo
    • Nivolumab
    • medguide required
  67. Tecentriq
    • Atezolizumab
    • medguide required
  68. Yervoy
    • Ipilumumab
    • REMS 
    • medguide required
  69. Sprycel
    Dasatinib
  70. Tasigna
    • Nilotinib
    • medguide required
  71. Iclusig
    • Ponatinib
    • medguide required
  72. Bosulif
    Bosutinib
  73. Zelboraf
    Vemurafenib
  74. Tafinlar
    Dabrafenib
  75. Mekinist
    Trametinib
  76. Cotellic
    Cobimetinib
  77. Gilotrif
    • Afatinib
    • dose adj for renal impairment
  78. Tarceva
    Erlotinib
  79. Iressa
    Gefitinib
  80. Xalkori
    • Crizotinib
    • ocular toxicity
  81. Zykadia
    • Ceritinib
    • pancreatitis
  82. Alecensa
    • Alectinib
    • myalgia and photosensitivity
  83. Tykerb
    • Lapatinib
    • must have HER2 overexpression to use
  84. NexAVAR
    Sorafenib
  85. Sutent
    • Sunitinib
    • hepatotoxicity
  86. take with food or within 1hr after meal
    • Gleevec
    • Thalomid
    • Xeloda
    • Aromasin
  87. Take on empty stomach (1h before or 2h after)
    • Tasigna
    • Tarceva
    • Nexavar
    • Tremodar
    • Zytiga
    • Pomalyst (2h before or 2h after food)
  88. Take without regard to food
    • Sprycel
    • Sutent
    • Nolvadex
    • Arimidex
    • Casodex
    • Relimid
    • Femara
Author
tiff.chan3
ID
343999
Card Set
Oncology 2
Description
onc
Updated