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Acid base buffer
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what are the basic buffer systems in the blood
bicarbonate (HCO3)
hemoglobin
protein
HPO4 2-
what are the acidic buffer systems in the blood
CO2
Hgb * H+
protein *H+
H2PO4 -
what is the hendersohn hasselbach equation
pka + Log [A-]/[HA]
what is the bicarbonate and pCO2 ratio of a normal person?
20:1
normal range for blood pH
7.35-7.45
normal range for pCO2
35-45 mmHg
normal range for [HCO3-]
22-26 mM
in what direction is HCO3 and PCO2 will be when body is compensating
same direction
what the equation for determining [CO2] and [O2]
[CO2]=d[CO2] = 0.03 x pCO2
[O2] = d[O2] = 0.03 x PO2
carbonic acid concentration in blood plasma equals
0.0307 mmol/L*mmHg x PCO2 mmHg
common factors that influence the amount of O2 that moves through the alveoli, blood and then tissue
destruction of alveoli
pulmonary edema
airway blockage
inadequate blood supply
diffusion of CO2 and O2
what is oxyhemoglobin (O2Hb)
O2 reversibly bound to hemogllobin
deoxyhemoglobin (HHb)
hemoglobin not bound to O2 but capable of forming a bond when O2 is available
carboxyhemoglobin (COHb)
hemoglobin bound to CO
methemoglobin (MetHb)
hemoglobin unable to bind O2 bc iron (Fe) is in an oxidized rather than reduced state
what is p50
the partial pressure of oxygen in the blood in which 50% of hemoglobin is saturated.
at 26.6 mmHg
Author
tanyalequang
ID
343437
Card Set
Acid base buffer
Description
acid base buffer
Updated
2018-11-07T19:02:22Z
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